YRC Public Data Repository - Protein Structure Prediction

Protein:	CYNS_ECOLI
Organism:	Escherichia coli
Length:	156 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYNS_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|76809590, gi\|... - gi\|76809590\|ref\|YP_334834.1\| cyanate hydratase [Burkholderia pseudomallei 1710b], gi\|76579043\|gb\|ABA...	261.0	[0..1]	[156..264]
CYNS_BURCM - Cyanate hydratase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=cynS PE=3 SV=1 CYNS_BURA4 - Cyanate hydratase OS=Burkholderia ambifaria (strain MC40-6) GN=cynS PE=3 SV=1	259.0	[0..1]	[156..1]
CYNS_BURM7 - Cyanate hydratase OS=Burkholderia mallei (strain NCTC 10247) GN=cynS PE=3 SV=1 CYNS_BURP6 - Cyanate hydratase OS=Burkholderia pseudomallei (strain 668) GN=cynS PE=3 SV=1 CYNS_BURMS - Cyanate hydratase OS=Burkholderia mallei (strain SAVP1) GN=cynS PE=3 SV=1 gi\|194520521, gi... - gi\|67761767\|ref\|ZP_00500473.1\| COG1513: Cyanate lyase [Burkholderia pseudomallei S13], gi\|254199115\|... CYNS_BURMA - Cyanate hydratase OS=Burkholderia mallei GN=cynS PE=3 SV=1 gi\|85065615 - gi\|85065615\|ref\|ZP_01026468.1\| COG1513: Cyanate lyase [Burkholderia mallei 10229] gi\|87313593, gi\|... - gi\|87313593\|ref\|ZP_01094680.1\| COG1513: Cyanate lyase [Burkholderia mallei 2002721280], gi\|100262639... gi\|83625623, gi\|... - gi\|83625623\|ref\|ZP_00935853.1\| COG1513: Cyanate lyase [Burkholderia mallei JHU], gi\|254208071\|ref\|ZP... gi\|100917417, gi... - gi\|67637801\|ref\|ZP_00436739.1\| COG1513: Cyanate lyase [Burkholderia mallei 10399], gi\|100917417\|ref\|... gi\|83621090, gi\|... - gi\|83621090\|ref\|ZP_00931502.1\| COG1513: Cyanate lyase [Burkholderia mallei FMH], gi\|254202729\|ref\|ZP... gi\|134248488, gi... - gi\|134280481\|ref\|ZP_01767192.1\| cyanate hydratase [Burkholderia pseudomallei 305], gi\|134248488\|gb\|E... gi\|67643552, gi\|... - gi\|67643552\|ref\|ZP_00442297.1\| cyanase [Burkholderia mallei GB8 horse 4], gi\|238524919\|gb\|EEP88349.1... gi\|160694839, gi... - gi\|254178925\|ref\|ZP_04885579.1\| cyanate hydratase [Burkholderia mallei ATCC 10399], gi\|194318226\|ref... CYNS_BURM9 - Cyanate hydratase OS=Burkholderia mallei (strain NCTC 10229) GN=cynS PE=3 SV=1 gi\|166998545, gi... - gi\|243065229\|gb\|EES47415.1\| cyanase [Burkholderia mallei PRL-20], gi\|166998545\|ref\|ZP_02264403.1\| cy... CYNS_BURMA - Cyanate hydratase OS=Burkholderia mallei (strain ATCC 23344) GN=cynS PE=3 SV=1	259.0	[0..1]	[156..1]
CYNS_BURP0 - Cyanate hydratase OS=Burkholderia pseudomallei (strain 1106a) GN=cynS PE=3 SV=1 gi\|82534173, gi\|... - gi\|90661808\|ref\|ZP_01249646.1\| hypothetical protein Bpse110_02006372 [Burkholderia pseudomallei 1106... CYNS_BURPS - Cyanate hydratase OS=Burkholderia pseudomallei GN=cynS PE=3 SV=1 gi\|67684701, gi\|... - gi\|90293311\|ref\|ZP_01212913.1\| hypothetical protein Bpse17_02001960 [Burkholderia pseudomallei 1710a... gi\|194508113, gi... - gi\|67755781\|ref\|ZP_00494671.1\| COG1513: Cyanate lyase [Burkholderia pseudomallei Pasteur], gi\|254190... gi\|100235782, gi... - gi\|83680104\|ref\|ZP_00941812.1\| COG1513: Cyanate lyase [Burkholderia pseudomallei 406e], gi\|254299283... gi\|254180631, gi... - gi\|99912809\|ref\|ZP_01319507.1\| hypothetical protein Bpse1_03001074 [Burkholderia pseudomallei 1655],... gi\|167817431 - gi\|167817431\|ref\|ZP_02449111.1\| cyanate hydratase [Burkholderia pseudomallei 91] gi\|167825838 - gi\|167825838\|ref\|ZP_02457309.1\| cyanate hydratase [Burkholderia pseudomallei 9] gi\|162210087 - gi\|162210087\|ref\|YP_334834.2\| cyanate hydratase [Burkholderia pseudomallei 1710b] gi\|226196848, gi... - gi\|226196848\|ref\|ZP_03792427.1\| cyanase [Burkholderia pseudomallei Pakistan 9], gi\|225931108\|gb\|EEH2... gi\|167740215 - gi\|167740215\|ref\|ZP_02412989.1\| cyanate hydratase [Burkholderia pseudomallei 14] CYNS_BURPS - Cyanate hydratase OS=Burkholderia pseudomallei (strain K96243) GN=cynS PE=3 SV=1 gi\|237813830, gi... - gi\|237813830\|ref\|YP_002898281.1\| cyanase [Burkholderia pseudomallei MSHR346], gi\|237502675\|gb\|ACQ949... gi\|167847321 - gi\|167847321\|ref\|ZP_02472829.1\| cyanate hydratase [Burkholderia pseudomallei B7210] gi\|167912556 - gi\|167912556\|ref\|ZP_02499647.1\| cyanate hydratase [Burkholderia pseudomallei 112]	257.0	[0..1]	[156..1]
CYNS_BURCH - Cyanate hydratase OS=Burkholderia cenocepacia (strain HI2424) GN=cynS PE=3 SV=1 CYNS_BURCA - Cyanate hydratase OS=Burkholderia cenocepacia (strain AU 1054) GN=cynS PE=3 SV=1 CYNS_BURCC - Cyanate hydratase OS=Burkholderia cenocepacia (strain MC0-3) GN=cynS PE=3 SV=1	257.0	[0..1]	[156..1]
gi\|124875717, gi... - gi\|84353710\|ref\|ZP_00978636.1\| COG1513: Cyanate lyase [Burkholderia cenocepacia PC184], gi\|254249216...	256.0	[0..1]	[156..1]
CYNS_PHOLL - Cyanate hydratase OS=Photorhabdus luminescens subsp. laumondii GN=cynS PE=3 SV=1 CYNS_PHOLL - Cyanate hydratase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01...	256.0	[0..1]	[156..1]
CYNS_BURVG - Cyanate hydratase OS=Burkholderia vietnamiensis (strain G4 / LMG 22486) GN=cynS PE=3 SV=1	256.0	[0..1]	[156..1]
CYNS_BURS3 - Cyanate hydratase OS=Burkholderia sp. (strain 383) GN=cynS PE=3 SV=1 CYNS_BURL3 - Cyanate hydratase OS=Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383) G...	256.0	[0..1]	[156..1]
CYNS_CHRVO - Cyanate hydratase OS=Chromobacterium violaceum GN=cynS PE=3 SV=1 CYNS_CHRVO - Cyanate hydratase OS=Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 1261...	254.0	[0..2]	[156..1]

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Predicted Domain #1

Region A:
Residues: [1-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQSQINRNI RLDLADAILL SKAKKDLSFA EIADGTGLAE AFVTAALLGQ QALPADAARL  60
   61 VGAKLDLDED SILLLQMIPL RGCIDDRIPT DPTMYRFYEM LQVYGTTLKA LVHEKFGDGI 120
  121 ISAINFKLDV KKVADPEGGE RAVITLDGKY LPTKPF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.69897
Match:	1dw9A
Description:	Cyanase N-terminal domain; Cyanase C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.47123111321218	bayes_pls_golite062009
nucleic acid binding	2.15040248098267	bayes_pls_golite062009
DNA binding	2.07628860569491	bayes_pls_golite062009
transcription regulator activity	1.1493158122876	bayes_pls_golite062009
transcription factor activity	0.48307037271624	bayes_pls_golite062009
protein binding	0.253677460522566	bayes_pls_golite062009
catalytic activity	0.00446472034106909	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: