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View Structure Prediction Details

Protein: DAAM1
Organism: Homo sapiens
Length: 1078 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAAM1.

Description E-value Query
Range
Subject
Range
gi|109083780 - gi|109083780|ref|XP_001093607.1| PREDICTED: similar to dishevelled-associated activator of morphogen...
0.0 [1..1078] [1..1078]
gi|3327146 - gi|3327146|dbj|BAA31641.1| KIAA0666 protein [Homo sapiens]
0.0 [1..1078] [8..1085]
gi|73963060 - gi|73963060|ref|XP_852088.1| PREDICTED: similar to dishevelled-associated activator of morphogenesis...
0.0 [1..1078] [1..1078]
gi|109479498, gi... - gi|109479498|ref|XP_001080564.1| PREDICTED: similar to Disheveled-associated activator of morphogene...
0.0 [1..1078] [1..1078]
gi|37360034 - gi|37360034|dbj|BAC97995.1| mKIAA0666 protein [Mus musculus]
0.0 [1..1078] [11..1087]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPRKRGGRG ISFIFCCFRN NDHPEITYRL RNDSNFALQT MEPALPMPPV EELDVMFSEL  60
   61 VDELDLTDKH REAMFALPAE KKWQIYCSKK KDQEENKGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.522879
Match: 1z2cB
Description: Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [100-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSWPEFYIDQ LNSMAARKSL LALEKEEEEE RSKTIESLKT ALRTKPMRFV TRFIDLDGLS  60
   61 CILNFLKTMD YETSESRIHT SLIGCIKALM NNSQGRAHVL AHSESINVIA QSLSTENIKT 120
  121 KVAVLEILGA VCLVPGGHKK VLQAMLHYQK YASERTRFQT LINDLDKSTG RYRDEVSLKT 180
  181 AIMSFINAVL SQGAGVESLD FRLHLRYEFL MLGIQPVIDK LREHENSTLD RHLDFFEMLR 240
  241 NEDELEFAKR FELVHIDTKS ATQMFELTRK RLTHSEAYPH FMSILHHCLQ MPYKRSGNTV 300
  301 QYWLLLDRII QQIVIQNDKG QDPDSTPLEN FNIKNVVRML VNENEVKQWK EQAEKMRKEH 360
  361 NELQQKLEKK ERECD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.0
Match: 2bnxA
Description: Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.373576425899935 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [475-603]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKTQEKEEMM QTLNKMKEKL EKETTEHKQV KQQVADLTAQ LHELSRRAVC ASIPGGPSPG  60
   61 APGGPFPSSV PGSLLPPPPP PPLPGGMLPP PPPPLPPGGP PPPPGPPPLG AIMPPPGAPM 120
  121 GLALKKKSI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.16
Match: 1pk8A
Description: Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [604-1078]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQPTNALKSF NWSKLPENKL EGTVWTEIDD TKVFKILDLE DLERTFSAYQ RQQDFFVNSN  60
   61 SKQKEADAID DTLSSKLKVK ELSVIDGRRA QNCNILLSRL KLSNDEIKRA ILTMDEQEDL 120
  121 PKDMLEQLLK FVPEKSDIDL LEEHKHELDR MAKADRFLFE MSRINHYQQR LQSLYFKKKF 180
  181 AERVAEVKPK VEAIRSGSEE VFRSGALKQL LEVVLAFGNY MNKGQRGNAY GFKISSLNKI 240
  241 ADTKSSIDKN ITLLHYLITI VENKYPSVLN LNEELRDIPQ AAKVNMTELD KEISTLRSGL 300
  301 KAVETELEYQ KSQPPQPGDK FVSVVSQFIT VASFSFSDVE DLLAEAKDLF TKAVKHFGEE 360
  361 AGKIQPDEFF GIFDQFLQAV SEAKQENENM RKKKEEEERR ARMEAQLKEQ RERERKMRKA 420
  421 KENSEESGEF DDLVSALRSG EVFDKDLSKL KRNRKRITNQ MTDSSRERPI TKLNF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 144.0
Match: 2j1dG
Description: No description for 2j1dG was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle