YRC Public Data Repository - Protein Structure Prediction

Protein:	DCD_ECOLI
Organism:	Escherichia coli
Length:	193 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DCD_ECOLI.

Description	E-value	Query Range	Subject Range
DCD_YERPA - Deoxycytidine triphosphate deaminase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=dcd PE=3 SV=... DCD_YERPN - Deoxycytidine triphosphate deaminase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=dcd PE=3 SV... gi\|167056813, gi... - gi\|167423964\|ref\|ZP_02315717.1\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Mediaev... gi\|167467521 - gi\|167467521\|ref\|ZP_02332225.1\| deoxycytidine triphosphate deaminase [Yersinia pestis FV-1] DCD_YERPY - Deoxycytidine triphosphate deaminase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=d... DCD_YERPB - Deoxycytidine triphosphate deaminase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=dc... gi\|166009184, gi... - gi\|166009184\|ref\|ZP_02230082.1\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Antiqua... DCD_YERPE - Deoxycytidine triphosphate deaminase OS=Yersinia pestis GN=dcd PE=3 SV=1 gi\|166207321, gi... - gi\|166211550\|ref\|ZP_02237585.1\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Antiqua... gi\|167050229, gi... - gi\|167400280\|ref\|ZP_02305793.1\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Antiqua... DCD_YERPS - Deoxycytidine triphosphate deaminase OS=Yersinia pseudotuberculosis GN=dcd PE=3 SV=1 gi\|167421824, gi... - gi\|167421824\|ref\|ZP_02313577.1\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Orienta... gi\|161511408 - gi\|161511408\|ref\|NP_992778.2\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Microtus ... DCD_YERPG - Deoxycytidine triphosphate deaminase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=dcd PE=3 SV=1 gi\|165923376, gi... - gi\|165924316\|ref\|ZP_02220148.1\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Orienta... gi\|165939553, gi... - gi\|165939553\|ref\|ZP_02228098.1\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Orienta... gi\|161484779 - gi\|161484779\|ref\|NP_669947.2\| deoxycytidine triphosphate deaminase [Yersinia pestis KIM] DCD_YERPS - Deoxycytidine triphosphate deaminase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=d... DCD_YERP3 - Deoxycytidine triphosphate deaminase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) ... gi\|115347277, gi... - gi\|218928666\|ref\|YP_002346541.1\| deoxycytidine triphosphate deaminase [Yersinia pestis CO92], gi\|161... gi\|149366446, gi... - gi\|149366446\|ref\|ZP_01888480.1\| deoxycytidine triphosphate deaminase [Yersinia pestis CA88-4125], gi... DCD_YERPP - Deoxycytidine triphosphate deaminase OS=Yersinia pestis (strain Pestoides F) GN=dcd PE=3 SV=1 gi\|229697872, gi... - gi\|229841506\|ref\|ZP_04461665.1\| 2'-deoxycytidine 5'-triphosphate deaminase [Yersinia pestis biovar O... gi\|229689225, gi... - gi\|229843617\|ref\|ZP_04463760.1\| 2'-deoxycytidine 5'-triphosphate deaminase [Yersinia pestis biovar O... gi\|229703679, gi... - gi\|229894281\|ref\|ZP_04509464.1\| 2'-deoxycytidine 5'-triphosphate deaminase [Yersinia pestis Pestoide...	227.0	[0..1]	[193..1]
gi\|77628756, gi\|... - gi\|77628756\|ref\|ZP_00791342.1\| COG0717: Deoxycytidine deaminase [Yersinia pseudotuberculosis IP 3175...	227.0	[0..1]	[193..6]
gi\|238789831, gi... - gi\|77975895\|ref\|ZP_00831429.1\| COG0717: Deoxycytidine deaminase [Yersinia frederiksenii ATCC 33641],...	227.0	[0..1]	[193..1]
DCD_PECAS - Deoxycytidine triphosphate deaminase OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672... DCD_ERWCT - Deoxycytidine triphosphate deaminase OS=Erwinia carotovora subsp. atroseptica GN=dcd PE=3 SV=1	226.0	[0..1]	[193..1]
gi\|77962473 - gi\|77962473\|ref\|ZP_00826293.1\| COG0717: Deoxycytidine deaminase [Yersinia mollaretii ATCC 43969]	226.0	[0..1]	[193..1]
gi\|89102634 - gi\|89102634\|ref\|ZP_01175253.1\| COG0717: Deoxycytidine deaminase [Yersinia pestis biovar Orientalis s... gi\|21959524, gi\|... - gi\|22126524\|ref\|NP_669947.1\| deoxycytidine triphosphate deaminase [Yersinia pestis KIM], gi\|21959524... gi\|77636277 - gi\|77636277\|ref\|ZP_00798352.1\| COG0717: Deoxycytidine deaminase [Yersinia pestis Angola] gi\|45436099, gi\|... - gi\|45441239\|ref\|NP_992778.1\| deoxycytidine triphosphate deaminase [Yersinia pestis biovar Microtus s...	225.0	[0..1]	[193..10]
gi\|238713650, gi... - gi\|77959269\|ref\|ZP_00823290.1\| COG0717: Deoxycytidine deaminase [Yersinia bercovieri ATCC 43970], gi...	225.0	[0..1]	[193..6]
gi\|238793467, gi... - gi\|77978855\|ref\|ZP_00834279.1\| COG0717: Deoxycytidine deaminase [Yersinia intermedia ATCC 29909], gi...	224.0	[0..1]	[193..6]
gi\|238895637, gi... - gi\|238895637\|ref\|YP_002920372.1\| deoxycytidine triphosphate deaminase [Klebsiella pneumoniae NTUH-K2... gi\|57753907 - gi\|57753907\|dbj\|BAD86762.1\| deoxycytidine triphosphate deaminase [Klebsiella pneumoniae] DCD_KLEP3 - Deoxycytidine triphosphate deaminase OS=Klebsiella pneumoniae (strain 342) GN=dcd PE=3 SV=1 DCD_KLEP7 - Deoxycytidine triphosphate deaminase OS=Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 ...	223.0	[0..1]	[193..1]
gi\|167551069, gi... - gi\|205324000\|gb\|EDZ11839.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteric... lcl\|NC_016856.1_... - [gene=dcd] [protein=deoxycytidine triphosphate deaminase] [protein_id=YP_005238158.1] [location=comp... DCD_SALCH - Deoxycytidine triphosphate deaminase OS=Salmonella choleraesuis (strain SC-B67) GN=dcd PE=3 SV=1 DCD_SALPA - Deoxycytidine triphosphate deaminase OS=Salmonella paratyphi A GN=dcd PE=3 SV=1 DCD_SALPA - Deoxycytidine triphosphate deaminase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=dcd PE... DCD_SALCH - Deoxycytidine triphosphate deaminase OS=Salmonella choleraesuis GN=dcd PE=3 SV=1 DCD_SALCH - Deoxycytidine triphosphate deaminase OS=Salmonella choleraesuis GN=dcd PE=3 SV=1 gi\|197242480, gi... - gi\|197264225\|ref\|ZP_03164299.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... DCD_SALPK - Deoxycytidine triphosphate deaminase OS=Salmonella paratyphi A (strain AKU_12601) GN=dcd PE=3 SV=1 DCD_SALDC - Deoxycytidine triphosphate deaminase OS=Salmonella dublin (strain CT_02021853) GN=dcd PE=3 SV=1 gi\|200388691, gi... - gi\|200388691\|ref\|ZP_03215303.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... DCD_SALHS - Deoxycytidine triphosphate deaminase OS=Salmonella heidelberg (strain SL476) GN=dcd PE=3 SV=1 DCD_SALTY - Deoxycytidine triphosphate deaminase OS=Salmonella typhimurium GN=dcd PE=3 SV=1 gi\|194472448, gi... - gi\|194472448\|ref\|ZP_03078432.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... DCD_SALTI - Deoxycytidine triphosphate deaminase OS=Salmonella typhi GN=dcd PE=3 SV=1 DCD_SALSV - Deoxycytidine triphosphate deaminase OS=Salmonella schwarzengrund (strain CVM19633) GN=dcd PE=3 SV=1 DCD_SALPB - Deoxycytidine triphosphate deaminase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=dcd ... DCD_SALA4 - Deoxycytidine triphosphate deaminase OS=Salmonella agona (strain SL483) GN=dcd PE=3 SV=1 gi\|205350641, gi... - gi\|205350641\|gb\|EDZ37272.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteric... gi\|168466219, gi... - gi\|195631263\|gb\|EDX49823.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteric... DCD_SALPB - Deoxycytidine triphosphate deaminase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=dcd ... gi\|168818188, gi... - gi\|205344962\|gb\|EDZ31726.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteric... DCD_SALNS - Deoxycytidine triphosphate deaminase OS=Salmonella newport (strain SL254) GN=dcd PE=3 SV=1 gi\|205330417, gi... - gi\|205330417\|gb\|EDZ17181.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteric... gi\|205335698, gi... - gi\|205335698\|gb\|EDZ22462.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteric... gi\|197290618, gi... - gi\|197290618\|gb\|EDY29973.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteric... gi\|168242196, gi... - gi\|205338653\|gb\|EDZ25417.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteric... DCD_SALPC - Deoxycytidine triphosphate deaminase OS=Salmonella paratyphi C (strain RKS4594) GN=dcd PE=3 SV=1 gi\|213647021 - gi\|213647021\|ref\|ZP_03377074.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... gi\|213864734 - gi\|213864734\|ref\|ZP_03386853.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... gi\|213980158 - gi\|213980158\|ref\|ZP_03407417.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... gi\|214000544 - gi\|214000544\|ref\|ZP_03411279.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... DCD_SALTY - Deoxycytidine triphosphate deaminase OS=Salmonella typhimurium GN=dcd PE=3 SV=1 gi\|213052467 - gi\|213052467\|ref\|ZP_03345345.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... gi\|213425526 - gi\|213425526\|ref\|ZP_03358276.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... gi\|213584639 - gi\|213584639\|ref\|ZP_03366465.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... gi\|213609874 - gi\|213609874\|ref\|ZP_03369700.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... gi\|204929060, gi... - gi\|204929060\|ref\|ZP_03220203.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... DCD_SALG2 - Deoxycytidine triphosphate deaminase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=dcd PE... DCD_SALEP - Deoxycytidine triphosphate deaminase OS=Salmonella enteritidis PT4 (strain P125109) GN=dcd PE=3 SV=1 gi\|213027294 - gi\|213027294\|ref\|ZP_03341741.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... DCD_SALTY - Deoxycytidine triphosphate deaminase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)... gi\|29141253, gi\|... - gi\|29141253\|ref\|NP_804595.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteri... gi\|238912550 - gi\|238912550\|ref\|ZP_04656387.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. ent... DCD_SALTI - Deoxycytidine triphosphate deaminase OS=Salmonella typhi GN=dcd PE=3 SV=1 gi\|16761050 - gi\|16761050\|ref\|NP_456667.1\| deoxycytidine triphosphate deaminase [Salmonella enterica subsp. enteri...	222.0	[0..1]	[193..1]

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Predicted Domain #1

Region A:
Residues: [1-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLCDRDIEA WLDEGRLSIN PRPPVERING ATVDVRLGNK FRTFRGHTAA FIDLSGPKDE  60
   61 VSAALDRVMS DEIVLDEGEA FYLHPGELAL AVTLESVTLP ADLVGWLDGR SSLARLGLMV 120
  121 HVTAHRIDPG WSGCIVLEFY NSGKLPLALR PGMLIGALSF EPLSGPAVRP YNRREDAKYR 180
  181 NQQGAVASRI DKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.69897
Match:	1xs1A
Description:	dCTP deaminase from Escherichia coli in complex with dUTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleoside-triphosphate diphosphatase activity	4.9446386219436	bayes_pls_golite062009
dUTP diphosphatase activity	4.92207428503442	bayes_pls_golite062009
dCTP deaminase activity	4.60235481565849	bayes_pls_golite062009
catalytic activity	1.71668532866244	bayes_pls_golite062009
hydrolase activity	1.63889579722321	bayes_pls_golite062009
deaminase activity	0.569997469329081	bayes_pls_golite062009
peroxisome proliferator activated receptor binding	0.383360698341246	bayes_pls_golite062009
binding	0.15452287545479	bayes_pls_golite062009
pyrimidine deoxyribonucleotide binding	0.0405835740740832	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: