YRC Public Data Repository - Protein Structure Prediction

Protein:	ERH_DANRE
Organism:	Danio rerio
Length:	104 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERH_DANRE.

Description	E-value	Query Range	Subject Range
gi\|73964238 - gi\|73964238\|ref\|XP_537493.2\| PREDICTED: similar to Enhancer of rudimentary homolog [Canis familiaris...	207.0	[0..1]	[104..53]
gi\|85543920, gi\|... - gi\|85543920\|pdb\|1WWQ\|A Chain A, Solution Structure Of Mouse Er, gi\|159163463\|pdb\|1WWQ\|A Chain A, Sol...	201.0	[0..1]	[104..8]
gi\|60653899, gi\|... - gi\|60653899\|gb\|AAX29642.1\| enhancer of rudimentary-like [synthetic construct], gi\|30583969\|gb\|AAP362...	197.0	[0..1]	[104..1]
gi\|6841073, gi\|1... - gi\|6841073\|gb\|AAF28892.1\|AF124330_1 enhancer of rudimentary homologue ERH [Xenopus laevis], gb\|AAH86... jgi\|Xentr4\|29327... - null gi\|114653669, gi... - gi\|55640957\|ref\|XP_510031.1\| PREDICTED: enhancer of rudimentary homolog isoform 2 [Pan troglodytes],... tr\|G1TKN7\|G1TKN7... - pep:novel chromosome:oryCun2:20:11583420:11583734:-1 gene:ENSOCUG00000025110 transcript:ENSOCUT00000... CCDS9794.1_1 - null gi\|109479584, gi... - gi\|187469487\|gb\|AAI66864.1\| Erh protein [Rattus norvegicus], gi\|149025016\|gb\|EDL81383.1\| rCG20904, i... ERH_MOUSE - Enhancer of rudimentary homolog OS=Mus musculus GN=Erh PE=1 SV=1 tr\|F7AUD4\|F7AUD4... - Enhancer of rudimentary homolog OS=Equus caballus OX=9796 GN=ERH PE=3 SV=1 gi\|194038479 - gi\|194038479\|ref\|XP_001926195.1\| PREDICTED: similar to enhancer of rudimentary homolog [Sus scrofa] gi\|61362236 - gi\|61362236\|gb\|AAX42183.1\| enhancer of rudimentary-like [synthetic construct] gi\|221220016, gi... - gi\|221220016\|gb\|ACM08669.1\| Enhancer of rudimentary homolog [Salmo salar], gi\|209730338\|gb\|ACI66038.... ERH_BOVIN - Enhancer of rudimentary homolog OS=Bos taurus GN=ERH PE=3 SV=1 ERH - enhancer of rudimentary homolog (Drosophila) gi\|109084078 - gi\|109084078\|ref\|XP_001109334.1\| PREDICTED: similar to Enhancer of rudimentary homolog [Macaca mulat... gi\|225714846 - gi\|225714846\|gb\|ACO13269.1\| Enhancer of rudimentary homolog [Esox lucius]	197.0	[0..1]	[104..1]
gi\|47940386 - gi\|47940386\|gb\|AAH71431.1\| Erh protein [Danio rerio]	194.0	[0..1]	[104..1]
gi\|57529979, gi\|... - gi\|57529979\|ref\|NP_001006475.1\| enhancer of rudimentary homolog [Gallus gallus], gi\|53136610\|emb\|CAG...	192.0	[0..1]	[104..1]
gi\|110748988 - gi\|110748988\|ref\|XP_001119900.1\| PREDICTED: similar to enhancer of rudimentary CG1871-PA, isoform A ...	191.0	[0..1]	[101..1]
ERH_AEDAE - Enhancer of rudimentary homolog OS=Aedes aegypti PE=3 SV=1	188.0	[0..1]	[100..1]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHTILLVQP TKRPEGRTYA DYESVNECME GVCKMYEEHL KRMNPNSPSI TYDISQLFDF  60
   61 VDDLADLSCL VYRADTQTYQ PYNKDWIKEK IYVLLRRQAQ QAGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.39794
Match:	1wwqA
Description:	Solution Structure of Mouse ER
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.65237304297126	bayes_pls_golite062009
binding	2.12725802590287	bayes_pls_golite062009
protein binding	0.757036133593613	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: