YRC Public Data Repository - Protein Structure Prediction

Protein:	FPG_ECOLI
Organism:	Escherichia coli
Length:	268 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FPG_ECOLI.

Description	E-value	Query Range	Subject Range
FPG_SHISS - Formamidopyrimidine-DNA glycosylase OS=Shigella sonnei (strain Ss046) GN=mutM PE=3 SV=3 gi\|124530495, gi... - gi\|124530495\|ref\|ZP_01701122.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli B], gi\|1244991... FPG_ECOLC - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=mu... FPG_ECO45 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=mutM PE=3 SV=... FPG_SHIBS - Formamidopyrimidine-DNA glycosylase OS=Shigella boydii serotype 4 (strain Sb227) GN=mutM PE=3 SV=3 FPG_ECO81 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O81 (strain ED1a) GN=mutM PE=3 SV=1 gi\|75242586, gi\|... - gi\|75242586\|ref\|ZP_00726330.1\| COG0266: Formamidopyrimidine-DNA glycosylase [Escherichia coli F11], ... FPG_ECOLU - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=mutM ... gi\|188487129, gi... - gi\|75514303\|ref\|ZP_00736611.1\| COG0266: Formamidopyrimidine-DNA glycosylase [Escherichia coli 53638]... gi\|15833764, gi\|... - gi\|15833764\|ref\|NP_312537.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. Saka... FPG_SHIF8 - Formamidopyrimidine-DNA glycosylase OS=Shigella flexneri serotype 5b (strain 8401) GN=mutM PE=3 SV=1 gi\|56480390, gi\|... - gi\|56480390\|ref\|NP_709414.2\| formamidopyrimidine-DNA glycosylase [Shigella flexneri 2a str. 301], gi... gi\|208814029, gi... - gi\|208814029\|ref\|ZP_03255358.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. E... gi\|208820753, gi... - gi\|208820753\|ref\|ZP_03261073.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. E... FPG_ECO5E - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=mutM PE=3 ... FPG_ECOSE - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli (strain SE11) GN=mutM PE=3 SV=1 FPG_ECO24 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=mutM PE=... FPG_ECO27 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=mutM PE=... gi\|191167823, gi... - gi\|75229026\|ref\|ZP_00715610.1\| COG0266: Formamidopyrimidine-DNA glycosylase [Escherichia coli B7A], ... gi\|217324519, gi... - gi\|217324519\|ref\|ZP_03440603.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. T... gi\|194430989, gi... - gi\|83571421\|ref\|ZP_00922861.1\| COG0266: Formamidopyrimidine-DNA glycosylase [Shigella dysenteriae 10... FPG_ESCF3 - Formamidopyrimidine-DNA glycosylase OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0... FPG_SHIB3 - Formamidopyrimidine-DNA glycosylase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=m... FPG_ECO8A - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O8 (strain IAI1) GN=mutM PE=3 SV=1 FPG_SHIFL - Formamidopyrimidine-DNA glycosylase OS=Shigella flexneri GN=mutM PE=3 SV=3 gi\|254795590, gi... - gi\|254795590\|ref\|YP_003080427.1\| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glyco... gi\|254038834, gi... - gi\|254038834\|ref\|ZP_04872886.1\| formamidopyrimidine-DNA glycosylase [Escherichia sp. 1_1_43], gi\|226... gi\|226902669, gi... - gi\|237703405\|ref\|ZP_04533886.1\| formamidopyrimidine-DNA glycosylase [Escherichia sp. 3_2_53FAA], gi\|... FPG_ECO57 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O157:H7 GN=mutM PE=3 SV=3 sp\|B7ULJ0\|FPG_ECO27 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=mutM PE=... gi\|168753459, gi... - gi\|189358964\|gb\|EDU77383.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. EC440... gi\|189369599, gi... - gi\|189369599\|gb\|EDU88015.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. EC450... gi\|189364460, gi... - gi\|189364460\|gb\|EDU82879.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. EC448... gi\|168772399, gi... - gi\|187771367\|gb\|EDU35211.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. EC419... gi\|189002553, gi... - gi\|189002553\|gb\|EDU71539.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. EC407... gi\|189374639, gi... - gi\|189374639\|gb\|EDU93055.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. EC869... FPG_ECOSM - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=mutM PE=3 SV=1 gi\|195936196 - gi\|195936196\|ref\|ZP_03081578.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. E... FPG_ECOUT - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli (strain UTI89 / UPEC) GN=mutM PE=3 SV=1 gi\|30065089, gi\|... - gi\|30065089\|ref\|NP_839260.1\| formamidopyrimidine-DNA glycosylase [Shigella flexneri 2a str. 2457T], ... gi\|209754676, gi... - pir\|\|G86039 formamidopyrimidine DNA glycosylase [imported] - Escherichia coli (strain O157:H7, subst... gi\|15804176, gi\|... - gi\|15804176\|ref\|NP_290215.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 EDL933], ... FPG_ECOK1 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O1:K1 / APEC GN=mutM PE=3 SV=1 gi\|188016969, gi... - gi\|188016969\|gb\|EDU55091.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. EC411...	383.0	[0..1]	[268..2]
gi\|193070399, gi... - gi\|75234793\|ref\|ZP_00719096.1\| COG0266: Formamidopyrimidine-DNA glycosylase [Escherichia coli E11001...	383.0	[0..1]	[268..2]
FPG_ECOL6 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O6 GN=mutM PE=3 SV=3 FPG_ECOL6 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) G... gi\|227883803, gi... - gi\|227883803\|ref\|ZP_04001608.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli 83972], gi\|227...	382.0	[0..1]	[268..2]
FPG_SHIDS - Formamidopyrimidine-DNA glycosylase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=mutM PE=3 S...	382.0	[0..1]	[268..2]
FPG_ECOL5 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=mutM PE=3 ...	382.0	[0..1]	[268..2]
FPG_ECODH - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli (strain K12 / DH10B) GN=mutM PE=3 SV=1 EG10329 - formamidopyrimidine /5-formyluracil / 5-hydroxymethyluracil DNA glycosylase / Formamidopyrimidine-DNA ... FPG_ECOBW - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=mutM PE=3 ... gi\|242379159, gi... - gi\|251786886\|ref\|YP_003001190.1\| hypothetical protein B21_03444 [Escherichia coli BL21], gi\|24237915... gi\|253771524, gi... - gi\|254290313\|ref\|YP_003056061.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli BL21(DE3)], g... gi\|254163563, gi... - gi\|254163563\|ref\|YP_003046671.1\| formamidopyrimidine-DNA glycosylase [Escherichia coli B str. REL606... gi\|83588518, gi\|... - gi\|83588518\|ref\|ZP_00927142.1\| COG0266: Formamidopyrimidine-DNA glycosylase [Escherichia coli 101-1]... FPG_ECOLI - Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23) (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidi... FPG_ECOHS - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli O9:H4 (strain HS) GN=mutM PE=3 SV=1 EG10329 - formamidopyrimidine /5-formyluracil / 5-hydroxymethyluracil DNA glycosylase / Formamidopyrimidine-DNA ... gi\|85676407, gi\|... - gi\|89110376\|ref\|AP_004156.1\| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosyla...	382.0	[0..1]	[268..2]
gi\|193063825, gi... - gi\|75258175\|ref\|ZP_00729623.1\| COG0266: Formamidopyrimidine-DNA glycosylase [Escherichia coli E22], ... gi\|75208028, gi\|... - gi\|75208028\|ref\|ZP_00708440.1\| COG0266: Formamidopyrimidine-DNA glycosylase [Escherichia coli B171],... FPG_ECO55 - Formamidopyrimidine-DNA glycosylase OS=Escherichia coli (strain 55989 / EAEC) GN=mutM PE=3 SV=1	381.0	[0..1]	[268..2]
FPG_SALTY - Formamidopyrimidine-DNA glycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) ... FPG_SALHS - Formamidopyrimidine-DNA glycosylase OS=Salmonella heidelberg (strain SL476) GN=mutM PE=3 SV=1 FPG_SALTY - Formamidopyrimidine-DNA glycosylase OS=Salmonella typhimurium GN=mutM PE=3 SV=3 gi\|167994347, gi... - gi\|205327810\|gb\|EDZ14574.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. enterica... gi\|205338984, gi... - gi\|205338984\|gb\|EDZ25748.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. enterica... gi\|205350455, gi... - gi\|205350455\|gb\|EDZ37086.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. enterica... lcl\|NC_016856.1_... - [gene=mutM] [protein=formamidopyrimidine-DNA glycosylase] [protein_id=YP_005239968.1] [location=comp... FPG_SALTY - Formamidopyrimidine-DNA glycosylase OS=Salmonella typhimurium GN=mutM PE=3 SV=3	378.0	[0..1]	[268..2]
gi\|197291486, gi... - gi\|197291486\|gb\|EDY30838.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. enterica... FPG_SALPA - Formamidopyrimidine-DNA glycosylase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=mutM PE... gi\|168818444, gi... - gi\|205344433\|gb\|EDZ31197.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. enterica... FPG_SALTI - Formamidopyrimidine-DNA glycosylase OS=Salmonella typhi GN=mutM PE=3 SV=3 FPG_SALTI - Formamidopyrimidine-DNA glycosylase OS=Salmonella typhi GN=mutM PE=3 SV=3 gi\|29144072, gi\|... - gi\|29144072\|ref\|NP_807414.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. enteric... gi\|16762583 - gi\|16762583\|ref\|NP_458200.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. enteric... FPG_SALPA - Formamidopyrimidine-DNA glycosylase OS=Salmonella paratyphi A GN=mutM PE=3 SV=3 gi\|213615651 - gi\|213615651\|ref\|ZP_03371477.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. ente... gi\|213999684 - gi\|213999684\|ref\|ZP_03410419.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. ente... FPG_SALG2 - Formamidopyrimidine-DNA glycosylase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=mutM PE... FPG_SALEP - Formamidopyrimidine-DNA glycosylase OS=Salmonella enteritidis PT4 (strain P125109) GN=mutM PE=3 SV=1 gi\|213161284 - gi\|213161284\|ref\|ZP_03346994.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. ente... gi\|213425232 - gi\|213425232\|ref\|ZP_03357982.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. ente... FPG_SALSV - Formamidopyrimidine-DNA glycosylase OS=Salmonella schwarzengrund (strain CVM19633) GN=mutM PE=3 SV=1 gi\|197241386, gi... - gi\|197263131\|ref\|ZP_03163205.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. ente... FPG_SALPK - Formamidopyrimidine-DNA glycosylase OS=Salmonella paratyphi A (strain AKU_12601) GN=mutM PE=3 SV=1 gi\|204321985, gi... - gi\|204928552\|ref\|ZP_03219751.1\| formamidopyrimidine-DNA glycosylase [Salmonella enterica subsp. ente...	377.0	[0..1]	[268..2]
FPG_SALCH - Formamidopyrimidine-DNA glycosylase OS=Salmonella choleraesuis GN=mutM PE=3 SV=3 FPG_SALCH - Formamidopyrimidine-DNA glycosylase OS=Salmonella choleraesuis GN=mutM PE=3 SV=3 FPG_SALCH - Formamidopyrimidine-DNA glycosylase OS=Salmonella choleraesuis (strain SC-B67) GN=mutM PE=3 SV=3	376.0	[0..1]	[268..2]

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Predicted Domain #1

Region A:
Residues: [1-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PELPEVETSR RGIEPHLVGA TILHAVVRNG RLRWPVSEEI YRLSDQPVLS VQRRAKYLLL  60
   61 ELPEGWIIIH LGMSGSLRIL PEELPPEKHD HVDLVMSNGK VLRYTDPRRF GAWLWTKELE 120
  121 GHNVLTHLGP EPLSDDFNGE YLHQKCAKKK TAIKPWLMDN KLVVGVGNIY ASESLFAAGI 180
  181 HPDRLASSLS LAECELLARV IKAVLLRSIE QGGTTLKDFL QSDGKPGYFA QELQVYGRKG 240
  241 EPCRVCGTPI VATKHAQRAT FYCRQCQK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	106.0
Match:	1k82A
Description:	DNA repair protein MutM (Fpg)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits