YRC Public Data Repository - Protein Structure Prediction

Protein:	FSAA_ECOLI
Organism:	Escherichia coli
Length:	220 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FSAA_ECOLI.

Description	E-value	Query Range	Subject Range
TAL_METJA - Probable transaldolase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM ... TAL_METJA - Probable transaldolase OS=Methanocaldococcus jannaschii GN=tal PE=3 SV=1	311.0	[0..1]	[212..1]
TAL_AQUAE - Probable transaldolase OS=Aquifex aeolicus (strain VF5) GN=tal PE=3 SV=1 TAL_AQUAE - Probable transaldolase OS=Aquifex aeolicus GN=tal PE=3 SV=1	311.0	[0..1]	[217..1]
TAL_METMP - Probable transaldolase OS=Methanococcus maripaludis (strain S2 / LL) GN=tal PE=3 SV=1 TAL_METMP - Probable transaldolase OS=Methanococcus maripaludis GN=tal PE=3 SV=1	309.0	[0..1]	[217..1]
TAL_GEOUR - Probable transaldolase OS=Geobacter uraniireducens (strain Rf4) GN=tal PE=3 SV=1	306.0	[0..1]	[214..1]
TAL_THEMA - Transaldolase OS=Thermotoga maritima GN=tal PE=1 SV=1 TAL_THEMA - Transaldolase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=tal PE=1 S...	304.0	[0..1]	[213..1]
gi\|58177039, gi\|... - gi\|58177049\|pdb\|1VPX\|T Chain T, Crystal Structure Of Transaldolase (Ec 2.2.1.2) (Tm0295) From Thermo...	304.0	[0..1]	[213..13]
TAL_ANADE - Probable transaldolase OS=Anaeromyxobacter dehalogenans (strain 2CP-C) GN=tal PE=3 SV=1	303.0	[0..1]	[214..1]
gi\|7473983 - gi\|7473983\|pir\|\|G75407 transaldolase - Deinococcus radiodurans (strain R1) gi\|15806354, gi\|... - gi\|6459090\|gb\|AAF10909.1\|AE001980_4 transaldolase [Deinococcus radiodurans R1], gi\|15806354\|ref\|NP_2...	301.0	[0..1]	[216..53]
gi\|115372648, gi... - gi\|115372648\|ref\|ZP_01459955.1\| transaldolase, putative [Stigmatella aurantiaca DW4/3-1], gi\|1153703...	299.0	[0..1]	[219..1]
gi\|83954477, gi\|... - gi\|83954477\|ref\|ZP_00963188.1\| Transaldolase [Sulfitobacter sp. NAS-14.1], gi\|83840761\|gb\|EAP79932.1...	299.0	[0..1]	[218..1]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELYLDTSDV VAVKALSRIF PLAGVTTNPS IIAAGKKPLD VVLPQLHEAM GGQGRLFAQV  60
   61 MATTAEGMVN DALKLRSIIA DIVVKVPVTA EGLAAIKMLK AEGIPTLGTA VYGAAQGLLS 120
  121 ALAGAEYVAP YVNRIDAQGG SGIQTVTDLH QLLKMHAPQA KVLAASFKTP RQALDCLLAG 180
  181 CESITLPLDV AQQMISYPAV DAAVAKFEQD WQGAFGRTSI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.522879
Match:	1l6wA
Description:	Fructose-6-phosphate aldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring aldehyde or ketonic groups	3.28746773527289	bayes_pls_golite062009
transaldolase activity	2.77878684721788	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	1.41110985630781	bayes_pls_golite062009
porphobilinogen synthase activity	0.658378297259497	bayes_pls_golite062009
fructose binding	0.427637212154492	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	0.0319140634878892	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: