YRC Public Data Repository - Protein Structure Prediction

Protein:	HYI_ECOLI
Organism:	Escherichia coli
Length:	258 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HYI_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|54309442, gi\|... - gi\|54309442\|ref\|YP_130462.1\| putative hydroxypyruvate isomerase [Photobacterium profundum SS9], gi\|4...	264.0	[0..1]	[257..6]
gi\|90413675, gi\|... - gi\|90413675\|ref\|ZP_01221664.1\| putative hydroxypyruvate isomerase [Photobacterium profundum 3TCK], g...	263.0	[0..1]	[257..1]
gi\|84386818, gi\|... - gi\|84386818\|ref\|ZP_00989843.1\| putative hydroxypyruvate isomerase [Vibrio splendidus 12B01], gi\|8437...	260.0	[0..1]	[258..1]
gi\|115258188, gi... - gi\|116253540\|ref\|YP_769378.1\| putative hydroxypyruvate isomerase [Rhizobium leguminosarum bv. viciae...	257.0	[0..1]	[257..1]
gi\|52420920 - gi\|52420920\|emb\|CAH55799.1\| putative regulatory protein GclR [Escherichia coli]	255.0	[0..1]	[256..1]
gi\|89359328, gi\|... - gi\|89359328\|ref\|ZP_01197149.1\| hydroxypyruvate isomerase [Xanthobacter autotrophicus Py2], gi\|893518...	253.0	[0..1]	[258..1]
gi\|91075553, gi\|... - gi\|91213979\|ref\|YP_543965.1\| putative regulatory protein GclR [Escherichia coli UTI89], gi\|91075553\|... gi\|117626642, gi... - gi\|117626642\|ref\|YP_859965.1\| putative regulatory protein GclR [Escherichia coli APEC O1], gi\|115515...	252.0	[0..1]	[256..1]
gi\|95109817 - gi\|95109817\|emb\|CAK14522.1\| hydroxypyruvate isomerase [Pseudomonas entomophila L48] gi\|104780830, gi... - gi\|95109817\|emb\|CAK14522.1\| hydroxypyruvate isomerase [Pseudomonas entomophila L48], gi\|104780830\|re...	252.0	[0..1]	[256..1]
gi\|205324165, gi... - gi\|205324165\|gb\|EDZ12004.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serovar S... gi\|205330943, gi... - gi\|205330943\|gb\|EDZ17707.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serovar 4... lcl\|NC_016856.1_... - [gene=gip] [protein=hydroxypyruvate isomerase] [protein_id=YP_005236221.1] [location=579955..580731] gi\|62126761, gi\|... - gi\|62179128\|ref\|YP_215545.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serovar ... gi\|224582356, gi... - gi\|224582356\|ref\|YP_002636154.1\| glyoxylate-induced protein [Salmonella enterica subsp. enterica ser... gi\|199602432, gi... - gi\|200389987\|ref\|ZP_03216598.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serov... gi\|206707800, gi... - gi\|207855997\|ref\|YP_002242648.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica sero... gi\|197239937, gi... - gi\|197261682\|ref\|ZP_03161756.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serov... gi\|197939421, gi... - gi\|198244905\|ref\|YP_002214474.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica sero... gi\|205344018, gi... - gi\|205344018\|gb\|EDZ30782.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serovar W... gi\|194442406, gi... - gi\|194442406\|ref\|YP_002039763.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica sero... gi\|16419028, gi\|... - gi\|16763898\|ref\|NP_459513.1\| hydroxypyruvate isomerase [Salmonella typhimurium LT2], gi\|16419028\|gb\|... gi\|168261039, gi... - gi\|205349746\|gb\|EDZ36377.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serovar H... gi\|195631637, gi... - gi\|195631637\|gb\|EDX50157.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serovar N... gi\|238911352 - gi\|238911352\|ref\|ZP_04655189.1\| hydroxypyruvate isomerase [Salmonella enterica subsp. enterica serov...	252.0	[0..1]	[258..1]

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Predicted Domain #1

Region A:
Residues: [1-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRFSANLSM LFGEYDFLAR FEKAAQCGFR GVEFMFPYDY DIEELKHVLA SNKLEHTLHN  60
   61 LPAGDWAAGE RGIACIPGRE EEFRDGVAAA IRYARALGNK KINCLVGKTP AGFSSEQIHA 120
  121 TLVENLRYAA NMLMKEDILL LIEPINHFDI PGFHLTGTRQ ALKLIDDVGC CNLKIQYDIY 180
  181 HMQRMEGELT NTMTQWADKI GHLQIADNPH RGEPGTGEIN YDYLFKVIEN SDYNGWVGCE 240
  241 YKPQTTTEAG LRWMDPYR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.0
Match:	1k77A
Description:	Hypothetical protein YgbM (EC1530)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.66019571685402	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: