YRC Public Data Repository - Protein Structure Prediction

Protein:	ISPH_BACAN
Organism:	Bacillus anthracis
Length:	316 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISPH_BACAN.

Description	E-value	Query Range	Subject Range
ISPH_PSEE4 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas entomophila (strain L48) GN=ispH P... gi\|95112630 - gi\|95112630\|emb\|CAK17358.1\| hydroxymethylbutenyl pyrophosphate reductase [Pseudomonas entomophila L4...	0.0	[1..309]	[1..307]
gi\|58425845, gi\|... - gi\|58581251\|ref\|YP_200267.1\| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Xanthomonas oryzae ...	0.0	[1..309]	[51..358]
ISPH_PSE14 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas savastanoi pv. phaseolicola (strai...	0.0	[1..309]	[1..307]
ISPH_PSEF5 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BA...	0.0	[1..309]	[1..307]
ISPH_PSEPG - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas putida (strain GB-1) GN=ispH PE=3 ... ISPH_PSEPK - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas putida (strain KT2440) GN=ispH PE=...	0.0	[1..309]	[1..307]
ISPH_PSEU2 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas syringae pv. syringae (strain B728...	0.0	[1..309]	[1..307]
tr\|E4RGR3\|E4RGR3... - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas putida (strain BIRD-1) GN=ispH PE=... tr\|I7BI70\|I7BI70... - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas putida (strain DOT-T1E) GN=ispH PE... ISPH_PSEP1 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas putida (strain F1 / ATCC 700007) G...	0.0	[1..309]	[1..307]
gi\|145269563, gi... - gi\|145637311\|ref\|ZP_01792972.1\| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Haemophilus infl... gi\|145268625, gi... - gi\|145634181\|ref\|ZP_01789892.1\| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Haemophilus infl... ISPH_HAEI8 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Haemophilus influenzae (strain 86-028NP) GN=is...	0.0	[1..314]	[1..312]
gi\|46129067 - gi\|46129067\|ref\|ZP_00201988.1\| COG0761: Penicillin tolerance protein [Haemophilus influenzae R2846]	0.0	[1..314]	[1..312]
ISPH_PSEPF - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas fluorescens (strain Pf0-1) GN=ispH...	0.0	[1..309]	[1..307]

Back

Predicted Domain #1

Region A:
Residues: [1-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIVKISPRG YCYGVVDAMV IARNAALDTS LPRPIYILGM IVHNKHVTDA FEEDGIITLD  60
   61 GPSRLDILDK IDSGTVIFTA HGVSPEVKQR AKEKGLTTID ATCPDVTKTH DLIEAKKAEG 120
  121 YHVIYIGKKN HPEPEGAVGI APDIVHLIER ADDLKTLEIP TDKILVTNQT TMSQWDVQHL 180
  181 MEDIQKKF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [189-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTAEFHKEIC LATQVRQEAV AKQADVADLT IVVGDPKSNN SNRLAQVSQE IAGTKAYRVA  60
   61 DVSEIKLEWL QGVENVAVTA GASTPTPITK EVIAFLEQYD PMNPATWERV RKVPLQKILP 120
  121 RVKVKKEQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.891	0.928	terpenoid biosynthetic process	c.2.1	NAD(P)-binding Rossmann-fold domains

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits