YRC Public Data Repository - Protein Structure Prediction

Protein:	CXCL2_RAT
Organism:	Rattus norvegicus
Length:	100 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CXCL2_RAT.

Description	E-value	Query Range	Subject Range
gi\|164665382, gi... - gi\|57527998\|ref\|NP_001009579.1\| chemokine (C-C motif) ligand 3-like 1 [Sus scrofa], gi\|49354682\|gb\|A...	97.0	[0..5]	[94..1]
CCL4_MACMU - C-C motif chemokine 4 OS=Macaca mulatta GN=CCL4 PE=2 SV=1	97.0	[0..5]	[94..1]
gi\|28894125 - gi\|28894125\|gb\|AAO52735.1\| monocyte chemoattractant protein-3 [Macaca nemestrina]	96.0	[0..1]	[99..5]
CCL4_BOVIN - C-C motif chemokine 4 OS=Bos taurus GN=CCL4 PE=3 SV=1	96.0	[0..5]	[94..1]
gi\|114671857 - gi\|114671857\|ref\|XP_001172226.1\| PREDICTED: similar to Small inducible cytokine A3-like 1 precursor ...	96.0	[0..6]	[94..42]
gi\|47779271, gi\|... - gi\|47779271\|ref\|NP_001001437.1\| chemokine (C-C motif) ligand 3-like 3 precursor [Homo sapiens], gi\|3... gi\|60656295 - gi\|60656295\|gb\|AAX32711.1\| chemokine (C-C motif) ligand 3-like 1 [synthetic construct]	95.0	[0..5]	[94..1]
gi\|30584489, gi\|... - gi\|60653245\|gb\|AAX29317.1\| chemokine (C-C motif) ligand 3-like 1 [synthetic construct], gi\|60653243\|...	95.0	[0..5]	[94..1]

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Predicted Domain #1

Region A:
Residues: [1-100]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPTRQLLN AVLVLLLLLA TNHQGTGVVV ASELRCQCLT TLPRVDFKNI QSLTVTPPGP  60
   61 HCAQTEVIAT LKDGHEVCLN PEAPLVQRIV QKILNKGKAN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.69897
Match:	1mi2A
Description:	Macrophage inflammatory protein-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytokine activity	8.07273475133641	bayes_pls_golite062009
chemokine activity	7.19574940007631	bayes_pls_golite062009
chemokine receptor binding	7.19574940007631	bayes_pls_golite062009
G-protein-coupled receptor binding	7.12866319987718	bayes_pls_golite062009
receptor binding	5.6737526433068	bayes_pls_golite062009
interleukin-8 receptor binding	3.11139680462527	bayes_pls_golite062009
chemoattractant activity	3.05299139114464	bayes_pls_golite062009
binding	2.73164240332813	bayes_pls_golite062009
glycosaminoglycan binding	2.45155021423769	bayes_pls_golite062009
protein binding	2.40339234127151	bayes_pls_golite062009
heparin binding	2.14306964280471	bayes_pls_golite062009
pattern binding	1.02739535268516	bayes_pls_golite062009
polysaccharide binding	0.8745248884958	bayes_pls_golite062009
CCR chemokine receptor binding	0.697359799598971	bayes_pls_golite062009
carbohydrate binding	0.49941396747283	bayes_pls_golite062009
CCR2 chemokine receptor binding	0.0620912591294003	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: