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View Structure Prediction Details

Protein: MSX2_RAT
Organism: Rattus norvegicus
Length: 139 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSX2_RAT.

Description E-value Query
Range
Subject
Range
gi|9621907 - gi|9621907|gb|AAF89581.1|AF165886_1 paired-box transcription factor [Branchiostoma floridae]
128.0 [0..3] [139..178]
gi|91087879 - gi|91087879|ref|XP_969925.1| PREDICTED: similar to transcription factor protein [Tribolium castaneum...
126.0 [0..2] [119..34]
MSX2_MOUSE - Homeobox protein MSX-2 OS=Mus musculus GN=Msx2 PE=1 SV=2
126.0 [0..1] [139..129]
gi|8248642 - gi|8248642|gb|AAC60657.2| Hox8 [Mus sp.]
125.0 [0..1] [139..129]
gi|228516, gi|63500 - gi|63500|emb|CAA44425.1| Hox-8 [Gallus gallus], gi|228516|prf||1805245B Hox8 gene
124.0 [0..1] [139..2]
gi|39850042 - gi|39850042|gb|AAH64202.1| Msx2 protein [Xenopus tropicalis]
124.0 [0..1] [139..145]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPTTCTLRK HKTNRKPRTP FTTSQLLALE RKFRQKQYLS IAERAEFSSS LNLTETQVKI  60
   61 WFQNRRAKAK RLQEAELEKL KMAAKPMLPS GFSLPFPINS PLQAASIYSA SYPFHRPVLP 120
  121 IPPVGLYATP VGYGMYHLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.0
Match: 1qryA
Description: VND/NK-2 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.09839603329852 bayes_pls_golite062009
DNA binding 3.70287146988839 bayes_pls_golite062009
nucleic acid binding 3.64380968064654 bayes_pls_golite062009
transcription factor activity 3.09799997792958 bayes_pls_golite062009
transcription repressor activity 2.67989581172015 bayes_pls_golite062009
binding 2.38790799849051 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.24140562598253 bayes_pls_golite062009
protein binding 1.88087411289001 bayes_pls_golite062009
sequence-specific DNA binding 1.50388788083093 bayes_pls_golite062009
transcription activator activity 0.868489910606103 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.83458785143486 bayes_pls_golite062009
chromatin binding 0.806325172844419 bayes_pls_golite062009
transcription corepressor activity 0.657260016132472 bayes_pls_golite062009
transcription factor binding 0.54291661516816 bayes_pls_golite062009
transcription cofactor activity 0.012862302676295 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle