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View Structure Prediction Details

Protein: MUTH_PHOLL
Organism: Photorhabdus luminescens subsp. laumondii
Length: 228 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUTH_PHOLL.

Description E-value Query
Range
Subject
Range
MUTH_SALCH - DNA mismatch repair protein MutH OS=Salmonella choleraesuis (strain SC-B67) GN=mutH PE=3 SV=1
MUTH_SALCH - DNA mismatch repair protein mutH OS=Salmonella choleraesuis GN=mutH PE=3 SV=1
MUTH_SALCH - DNA mismatch repair protein mutH OS=Salmonella choleraesuis GN=mutH PE=3 SV=1
MUTH_SALPC - DNA mismatch repair protein MutH OS=Salmonella paratyphi C (strain RKS4594) GN=mutH PE=3 SV=1
388.0 [0..1] [228..1]

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Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTLFSPPSP PDNEQQLFEC AQLLAGLSMG ELAAKANLPI PPNLKRDKGW VGMLLEYYLG  60
   61 ASAGSKPEQD FEHIGIELKT IPVDRRGYPL ETTFVCVAPL TGNSGITWGS CHVRRKLSRV 120
  121 LWIPVEGERE IPLAKRRVGS PLLWSPNQEE EELLRRDWEE LMDFIVLGKV ESVTARHGEV 180
  181 LQLRPKAANS KALTEAIGVH GQPIMTLPRG FYLRKNFTAP LLARHFLI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.0
Match: 2azoA
Description: DNA mismatch repair protein MutH from
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
double-stranded DNA binding 4.65596322324967 bayes_pls_golite062009
endodeoxyribonuclease activity 3.88121538069074 bayes_pls_golite062009
single-stranded DNA specific endodeoxyribonuclease activity 3.87045877570028 bayes_pls_golite062009
deoxyribonuclease activity 3.62965779224499 bayes_pls_golite062009
single-stranded DNA binding 2.01277239394854 bayes_pls_golite062009
structure-specific DNA binding 1.99560174672253 bayes_pls_golite062009
nuclease activity 1.92659045080864 bayes_pls_golite062009
endonuclease activity 1.6546965422816 bayes_pls_golite062009
damaged DNA binding 1.50475020123562 bayes_pls_golite062009
hydrolase activity 1.18004254197954 bayes_pls_golite062009
binding 0.940513659936693 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.878597940882332 bayes_pls_golite062009
catalytic activity 0.816447099398022 bayes_pls_golite062009
nucleic acid binding 0.796780585758145 bayes_pls_golite062009
DNA binding 0.779318309058729 bayes_pls_golite062009
protein binding 0.458550636208588 bayes_pls_golite062009
DNA strand annealing activity 0.103710151681167 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle