YRC Public Data Repository - Protein Structure Prediction

Protein:	NFSA_ECOLI
Organism:	Escherichia coli
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NFSA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|149749440, gi... - gi\|153837300\|ref\|ZP_01989967.1\| NADPH-flavin oxidoreductase [Vibrio parahaemolyticus AQ3810], gi\|149... gi\|28810003 - gi\|28810003\|dbj\|BAC62944.1\| NADPH-flavin oxidoreductase [Vibrio parahaemolyticus RIMD 2210633] gi\|28810003, gi\|... - gi\|28901456\|ref\|NP_801111.1\| nitroreductase A [Vibrio parahaemolyticus RIMD 2210633], gi\|28810003\|db...	257.0	[0..1]	[240..1]
gi\|194541372, gi... - gi\|75855076\|ref\|ZP_00762739.1\| COG0778: Nitroreductase [Vibrio sp. Ex25], gi\|254227315\|ref\|ZP_049207...	257.0	[0..1]	[240..1]
gi\|91191957, gi\|... - gi\|91223144\|ref\|ZP_01258410.1\| NADPH-flavin oxidoreductase [Vibrio alginolyticus 12G01], gi\|91191957...	254.0	[0..1]	[240..1]
FRP_VIBHA - NADPH-flavin oxidoreductase OS=Vibrio harveyi GN=frp PE=1 SV=1	251.0	[0..1]	[240..1]
gi\|84386502, gi\|... - gi\|84386502\|ref\|ZP_00989529.1\| NADPH-flavin oxidoreductase [Vibrio splendidus 12B01], gi\|84378607\|gb...	246.0	[0..1]	[240..1]
gi\|85837595, gi\|... - gi\|86144696\|ref\|ZP_01063028.1\| NADPH-flavin oxidoreductase [Vibrio sp. MED222], gi\|85837595\|gb\|EAQ55...	245.0	[0..1]	[240..1]
gi\|21666485 - gi\|21666485\|gb\|AAM73721.1\|AF395832_1 glutathione-S-transferase/nitroreductase fusion protein [synthe...	245.0	[0..2]	[240..227]
gi\|88800153, gi\|... - gi\|88800153\|ref\|ZP_01115722.1\| Nitroreductase [Reinekea sp. MED297], gi\|88777134\|gb\|EAR08340.1\| Nitr...	243.0	[0..1]	[240..1]
gi\|90413076, gi\|... - gi\|90413076\|ref\|ZP_01221073.1\| hypothetical NADPH-flavin oxidoreductase [Photobacterium profundum 3T...	240.0	[0..1]	[240..1]
gi\|46914021, gi\|... - gi\|54309583\|ref\|YP_130603.1\| nitroreductase A [Photobacterium profundum SS9], gi\|46914021\|emb\|CAG208...	240.0	[0..1]	[240..3]

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Predicted Domain #1

Region A:
Residues: [1-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPTIELICG HRSIRHFTDE PISEAQREAI INSARATSSS SFLQCSSIIR ITDKALREEL  60
   61 VTLTGGQKHV AQAAEFWVFC ADFNRHLQIC PDAQLGLAEQ LLLGVVDTAM MAQNALIAAE 120
  121 SLGLGGVYIG GLRNNIEAVT KLLKLPQHVL PLFGLCLGWP ADNPDLKPRL PASILVHENS 180
  181 YQPLDKGALA QYDEQLAEYY LTRGSNNRRD TWSDHIRRTI IKESRPFILD YLHKQGWATR 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.522879
Match:	1f5vA
Description:	Oxygen-insensitive NAD(P)H nitroreductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.48193963005483	bayes_pls_golite062009
oxidoreductase activity	0.480695441264854	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: