YRC Public Data Repository - Protein Structure Prediction

Protein:	NUSG_MYCLE
Organism:	Mycobacterium leprae
Length:	228 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUSG_MYCLE.

Description	E-value	Query Range	Subject Range
gi\|215402414 - gi\|215402414\|ref\|ZP_03414595.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|194543022, gi... - gi\|81255499\|ref\|ZP_00879975.1\| COG0250: Transcription antiterminator [Mycobacterium tuberculosis C],... gi\|119700503, gi... - gi\|76785663\|ref\|ZP_00772828.1\| COG0250: Transcription antiterminator [Mycobacterium tuberculosis F11... gi\|148660413, gi... - gi\|167969069\|ref\|ZP_02551346.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254363593, gi... - gi\|254363593\|ref\|ZP_04979639.1\| transcription antitermination protein nusG [Mycobacterium tuberculos... gi\|121636560, gi... - gi\|121636560\|ref\|YP_976783.1\| transcription antitermination protein NusG [Mycobacterium bovis BCG st... gi\|255098156 - gi\|255098156\|ref\|ZP_05327634.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254817182 - gi\|254817182\|ref\|ZP_05222183.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254549599 - gi\|254549599\|ref\|ZP_05140046.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|253797579, gi... - gi\|253797579\|ref\|YP_003030580.1\| transcription antitermination protein nusG [Mycobacterium tuberculo... gi\|215410186 - gi\|215410186\|ref\|ZP_03418994.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|215429474 - gi\|215429474\|ref\|ZP_03427393.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|215444758 - gi\|215444758\|ref\|ZP_03431510.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|218752287 - gi\|218752287\|ref\|ZP_03531083.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... NUSG_MYCTU - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis (strain ATCC 25... gi\|219556483 - gi\|219556483\|ref\|ZP_03535559.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... NUSG_MYCBO - Transcription antitermination protein nusG OS=Mycobacterium bovis GN=nusG PE=3 SV=1 NUSG_MYCBO - Transcription termination/antitermination protein NusG OS=Mycobacterium bovis (strain ATCC BAA-935 /... gi\|224989032, gi... - gi\|224989032\|ref\|YP_002643719.1\| transcription antitermination protein [Mycobacterium bovis BCG str.... NUSG_MYCTU - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis GN=nusG PE=1 SV... NUSG_MYCTO - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis (strain CDC 155...	250.0	[0..2]	[228..12]
gi\|254776958 - gi\|254776958\|ref\|ZP_05218474.1\| transcription antitermination protein NusG [Mycobacterium avium subs... gi\|41410209, gi\|... - gi\|41410209\|ref\|NP_963045.1\| transcription antitermination protein NusG [Mycobacterium avium subsp. ... gi\|118167394, gi... - gi\|118466107\|ref\|YP_883656.1\| transcription antitermination protein NusG [Mycobacterium avium 104], ...	247.0	[0..11]	[228..39]
gi\|89338459, gi\|... - gi\|89338459\|ref\|ZP_01191224.1\| transcription antitermination protein NusG:KOW [Mycobacterium flavesc...	237.0	[0..1]	[228..46]
gi\|110818507, gi... - gi\|111018977\|ref\|YP_701949.1\| transcription antitermination protein NusG [Rhodococcus jostii RHA1], ...	233.0	[0..2]	[228..38]
gi\|54027090, gi\|... - gi\|54027090\|ref\|YP_121332.1\| transcription antitermination protein NusG [Nocardia farcinica IFM 1015...	230.0	[0..2]	[228..45]
gi\|38233045 - gi\|38233045\|ref\|NP_938812.1\| transcription antitermination protein NusG [Corynebacterium diphtheriae... gi\|38199304 - gi\|38199304\|emb\|CAE48935.1\| Putative transcription antitermination protein [Corynebacterium diphther...	230.0	[0..1]	[228..35]
gi\|92913607, gi\|... - gi\|92913607\|ref\|ZP_01282235.1\| transcription antitermination protein NusG:KOW [Mycobacterium sp. KMS... gi\|108797896, gi... - gi\|108797896\|ref\|YP_638093.1\| transcription antitermination protein NusG [Mycobacterium sp. MCS], gi...	227.0	[0..2]	[228..43]
gi\|84384306, gi\|... - gi\|84494813\|ref\|ZP_00993932.1\| transcription antitermination protein NusG [Janibacter sp. HTCC2649],...	225.0	[0..3]	[228..94]
gi\|48835068 - ref\|ZP_00292070.1\| COG0250: Transcription antiterminator [Thermobifida fusca] gi\|72163058, gi\|... - gi\|72163058\|ref\|YP_290715.1\| transcription antitermination protein NusG [Thermobifida fusca YX], gi\|...	225.0	[0..11]	[228..44]
gi\|109942286\|emb... - NusG protein [Streptomyces clavuligerus] gi\|109942286 - gi\|109942286\|emb\|CAJ84542.1\| NusG protein [Streptomyces clavuligerus]	223.0	[0..2]	[227..68]

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Predicted Domain #1

Region A:
Residues: [1-93]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEAGIDEFA AGGGHVEPAA EVDPAAALKA ELRSKPGDWY VIHSYAGYEN KVKANLETRV  60
   61 QNLDVGDCIF QVEVPTEEVT EIKNGQRRLV NRK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.31
Match:	1m1gA
Description:	N-utilization substance G protein NusG, insert domain; N-utilization substance G protein NusG, C-terminal domain; N-utilization substance G protein NusG, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [94-228]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLPGYILVRM DLTDDSWAAV RNTPGVTGFV GATSRPSALA LDDVVKFLLP SGSAKKDAKG  60
   61 AVSTAAAAEA GGLERSIIEV DYEVGESVTV MDGPFATLPA TISEVNAEQQ KLKVLVSIFG 120
  121 RETPVELTFS QVSKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.09691
Match:	1m1gA
Description:	N-utilization substance G protein NusG, insert domain; N-utilization substance G protein NusG, C-terminal domain; N-utilization substance G protein NusG, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription termination factor activity	7.3828495299519	bayes_pls_golite062009
transcription regulator activity	3.63525538465601	bayes_pls_golite062009
structural constituent of ribosome	2.40236111142017	bayes_pls_golite062009
structural molecule activity	2.11748533169546	bayes_pls_golite062009
nucleic acid binding	0.761013355804059	bayes_pls_golite062009
binding	0.302568764609847	bayes_pls_golite062009
DNA binding	0.302556727687398	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: