YRC Public Data Repository - Protein Structure Prediction

Protein:	POTI_ECOLI
Organism:	Escherichia coli
Length:	281 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POTI_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|67548364, gi\|... - gi\|67548364\|ref\|ZP_00426254.1\| Binding-protein-dependent transport systems inner membrane component ...	182.0	[0..25]	[271..536]
gi\|89359528, gi\|... - gi\|89359528\|ref\|ZP_01197349.1\| similar to ABC-type spermidine/putrescine transport system permease c...	168.0	[0..6]	[265..301]
gi\|23100928, gi\|... - gi\|23100928\|ref\|NP_694395.1\| ABC transporter permease [Oceanobacillus iheyensis HTE831], gi\|22779163...	166.0	[0..37]	[264..185]
gi\|110670165, gi... - gi\|110670165\|ref\|YP_666722.1\| polyamine transporter, subunit I, ABC transporter, membrane protein [F... gi\|254370201, gi... - gi\|254370201\|ref\|ZP_04986207.1\| polyamine transporter [Francisella tularensis subsp. tularensis FSC0... gi\|254840506, gi... - gi\|254874507\|ref\|ZP_05247217.1\| polyamine transporter [Francisella tularensis subsp. tularensis MA00... gi\|56604186, gi\|... - gi\|56707694\|ref\|YP_169590.1\| polyamine transporter, subunit I, ABC transporter, membrane protein [Fr...	164.0	[0..8]	[271..3]
gi\|91779159, gi\|... - gi\|91779159\|ref\|YP_554367.1\| ABC putrescine transporter, inner membrane subunit PotI [Burkholderia x...	163.0	[0..15]	[280..12]
gi\|89143900, gi\|... - gi\|89256069\|ref\|YP_513431.1\| polyamine transporter, subunit I, ABC transporter, membrane protein [Fr... gi\|197741997, gi... - gi\|254367404\|ref\|ZP_04983430.1\| polyamine transporter, subunit I, ABC transporter, membrane protein ... gi\|156502082, gi... - gi\|156502082\|ref\|YP_001428147.1\| ABC transporter, permease protein [Francisella tularensis subsp. ho... gi\|89143900\|emb\|... - polyamine transporter, subunit I, ABC transporter, membrane protein [Francisella tularensis subsp. h... gi\|115314546, gi... - gi\|115314546\|ref\|YP_763269.1\| polyamine ABC transporter ATP-binding protein [Francisella tularensis ... gi\|167009283 - gi\|167009283\|ref\|ZP_02274214.1\| ABC transporter, permease protein [Francisella tularensis subsp. hol...	163.0	[0..8]	[271..3]
gi\|77965343, gi\|... - gi\|78060793\|ref\|YP_367368.1\| ABC spermidine/putrescine transporter, inner membrane subunit [Burkhold...	161.0	[0..5]	[281..2]
gi\|42522758, gi\|... - gi\|42522758\|ref\|NP_968138.1\| maltose/maltodextrin transport permease homologue [Bdellovibrio bacteri...	161.0	[0..6]	[256..448]
gi\|115360809, gi... - gi\|74017399\|ref\|ZP_00688023.1\| Binding-protein-dependent transport systems inner membrane component ...	160.0	[0..5]	[281..2]

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Predicted Domain #1

Region A:
Residues: [1-281]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNLPVVRSP WRIVILLLGF TFLYAPMLML VIYSFNSSKL VTVWAGWSTR WYGELLRDDA  60
   61 MMSAVGLSLT IAACAATAAA ILGTIAAVVL VRFGRFRGSN GFAFMITAPL VMPDVITGLS 120
  121 LLLLFVALAH AIGWPADRGM LTIWLAHVTF CTAYVAVVIS SRLRELDRSI EEAAMDLGAT 180
  181 PLKVFFVITL PMIMPAIISG WLLAFTLSLD DLVIASFVSG PGATTLPMLV FSSVRMGVNP 240
  241 EINALATLIL GAVGIVGFIA WYLMARAEKQ RIRDIQRARR G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.522879
Match:	2onkC
Description:	No description for 2onkC was found.

Predicted functions:

Term	Confidence	Notes
transporter activity	4.47791794099048	bayes_pls_golite062009
transmembrane transporter activity	4.39634414867723	bayes_pls_golite062009
primary active transmembrane transporter activity	4.00217276617164	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	3.99891866007599	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	3.98211391811154	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	3.97908815673888	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	3.97858487787769	bayes_pls_golite062009
substrate-specific transporter activity	3.91409799494188	bayes_pls_golite062009
active transmembrane transporter activity	3.89128503869358	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.86345398417242	bayes_pls_golite062009
ATPase activity, coupled	3.32937863234927	bayes_pls_golite062009
ATPase activity	3.08226330066871	bayes_pls_golite062009
nucleoside-triphosphatase activity	3.00619776756793	bayes_pls_golite062009
pyrophosphatase activity	2.93295939960055	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.91418221359376	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.91133868200651	bayes_pls_golite062009
ion transmembrane transporter activity	2.70116960945763	bayes_pls_golite062009
cation transmembrane transporter activity	1.82526327874202	bayes_pls_golite062009
hydrolase activity	1.57867403354317	bayes_pls_golite062009
amine transmembrane transporter activity	1.35745015743741	bayes_pls_golite062009
secondary active transmembrane transporter activity	0.96228415837358	bayes_pls_golite062009
organic acid transmembrane transporter activity	0.86220210518613	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	0.851725653994868	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.69074662322395	bayes_pls_golite062009
symporter activity	0.483541714040201	bayes_pls_golite062009
solute:cation symporter activity	0.483541714040201	bayes_pls_golite062009
catalytic activity	0.427775057748038	bayes_pls_golite062009
anion transmembrane transporter activity	0.38505555521505	bayes_pls_golite062009
sulfur amino acid transmembrane transporter activity	0.197768400248901	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	0.171737154712589	bayes_pls_golite062009
sugar transmembrane transporter activity	0.149318428666465	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.14639856424105	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	0.0202682073710961	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: