YRC Public Data Repository - Protein Structure Prediction

Protein:	PUR3_ECOLI
Organism:	Escherichia coli
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PUR3_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|88795665, gi\|... - gi\|88795665\|ref\|ZP_01111358.1\| phosphoribosylglycinamide formyltransferase [Alteromonas macleodii 'D...	250.0	[0..2]	[211..7]
gi\|77958968 - gi\|77958968\|ref\|ZP_00822993.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase...	244.0	[0..1]	[212..3]
gi\|77960046, gi\|... - gi\|77960046\|ref\|ZP_00823945.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase...	241.0	[0..2]	[211..3]
gi\|85694914, gi\|... - gi\|85711413\|ref\|ZP_01042472.1\| Folate-dependent phosphoribosylglycinamide formyltransferase [Idiomar...	241.0	[0..2]	[212..3]
gi\|71145720, gi\|... - gi\|71279980\|ref\|YP_269893.1\| phosphoribosylglycinamide formyltransferase [Colwellia psychrerythraea ...	241.0	[0..2]	[211..4]
gi\|187770629, gi... - gi\|187770629\|gb\|EDU34473.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 st... gi\|168768591, gi... - gi\|189362258\|gb\|EDU80677.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 st... gi\|189368400, gi... - gi\|189368400\|gb\|EDU86816.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 st... gi\|168756271, gi... - gi\|189356635\|gb\|EDU75054.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 st... gi\|15832616, gi\|... - gi\|15832616\|ref\|NP_311389.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 s... gi\|195936643 - gi\|195936643\|ref\|ZP_03082025.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H... gi\|189378680, gi... - gi\|189378680\|gb\|EDU97096.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 st... gi\|168787845, gi... - gi\|189372372\|gb\|EDU90788.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 st... gi\|189003542, gi... - gi\|189003542\|gb\|EDU72528.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 st... gi\|168748442, gi... - gi\|188017158\|gb\|EDU55280.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 st... gi\|15832616, gi\|... - gi\|15832616\|ref\|NP_311389.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7],... gi\|209763526, gi... - pir\|\|B91049 phosphoribosylglycinamide formyltransferase 1 [imported] - Escherichia coli (strain O157... gi\|209157188, gi... - gi\|209395788\|ref\|YP_002271969.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:... gi\|208741350, gi... - gi\|208821227\|ref\|ZP_03261547.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H... gi\|254593845, gi... - gi\|254794445\|ref\|YP_003079282.1\| phosphoribosylglycinamide formyltransferase 1 [Escherichia coli O15... gi\|208812986, gi... - gi\|208812986\|ref\|ZP_03254315.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H... gi\|208807689, gi... - gi\|208807689\|ref\|ZP_03250026.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H... gi\|217327058, gi... - gi\|217327058\|ref\|ZP_03443141.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H...	241.0	[0..1]	[212..1]
gi\|227835880, gi... - gi\|227887530\|ref\|ZP_04005335.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli 83972]... gi\|226901372, gi... - gi\|237705006\|ref\|ZP_04535487.1\| phosphoribosylglycinamide formyltransferase [Escherichia sp. 3_2_53F... gi\|26109266, gi\|... - gi\|26248860\|ref\|NP_754900.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli CFT073], ... gi\|10186020, gi\|... - gi\|10186020\|gb\|AAG14578.1\|AF293164_2 phosphoribosylglycinamide formyltransferase 1 [Escherichia coli... gi\|117624684, gi... - gi\|117624684\|ref\|YP_853597.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli APEC O1]... gi\|170683963, gi... - gi\|170683963\|ref\|YP_001744684.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli SMS-3... gi\|75240138, gi\|... - gi\|75240138\|ref\|ZP_00724097.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase... gi\|218366193, gi... - gi\|218559424\|ref\|YP_002392337.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli S88],... gi\|91073395, gi\|... - gi\|91211821\|ref\|YP_541807.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli UTI89], g... gi\|218690615, gi... - gi\|218690615\|ref\|YP_002398827.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli ED1a]... gi\|110642662, gi... - gi\|110642662\|ref\|YP_670392.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli 536], gi... gi\|218700957, gi... - gi\|218700957\|ref\|YP_002408586.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli IAI39...	240.0	[0..1]	[212..1]
gi\|10186041 - gi\|10186041\|gb\|AAG14592.1\|AF293171_2 phosphoribosylglycinamide formyltransferase 1 [Escherichia coli... gi\|74313026, gi\|... - gi\|74313026\|ref\|YP_311445.1\| phosphoribosylglycinamide formyltransferase [Shigella sonnei Ss046], gi...	240.0	[0..1]	[212..1]
gi\|82777879, gi\|... - gi\|82777879\|ref\|YP_404228.1\| phosphoribosylglycinamide formyltransferase [Shigella dysenteriae Sd197... gi\|10186023 - gi\|10186023\|gb\|AAG14580.1\|AF293165_2 phosphoribosylglycinamide formyltransferase 1 [Escherichia coli...	240.0	[0..1]	[212..1]
gi\|24113828, gi\|... - gi\|24113828\|ref\|NP_708338.1\| phosphoribosylglycinamide formyltransferase [Shigella flexneri 2a str. ... gi\|30063874, gi\|... - gi\|30063874\|ref\|NP_838045.1\| phosphoribosylglycinamide formyltransferase [Shigella flexneri 2a str. ... gi\|209913236, gi... - gi\|209919977\|ref\|YP_002294061.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli SE11]... gi\|218361793, gi... - gi\|218555025\|ref\|YP_002387938.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli IAI1]... gi\|218696127, gi... - gi\|218696127\|ref\|YP_002403794.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli 55989... gi\|10186164, gi\|... - gi\|10186164\|gb\|AAG14674.1\|AF293212_2 phosphoribosylglycinamide formyltransferase 1 [Escherichia coli... gi\|218433096, gi... - gi\|218705999\|ref\|YP_002413518.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli UMN02... gi\|253974375, gi... - gi\|254162474\|ref\|YP_003045582.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli B str... gi\|254289235, gi... - gi\|254289235\|ref\|YP_003054983.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli BL21(... gi\|251785825, gi... - gi\|251785825\|ref\|YP_003000129.1\| hypothetical protein B21_02354 [Escherichia coli BL21], gi\|24237809... gi\|110806430, gi... - gi\|110806430\|ref\|YP_689950.1\| phosphoribosylglycinamide formyltransferase [Shigella flexneri 5 str. ... gi\|157079726, gi... - gi\|75187252\|ref\|ZP_00700519.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase... gi\|75211467, gi\|... - gi\|75211467\|ref\|ZP_00711557.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase... gi\|124531261, gi... - gi\|124531261\|ref\|ZP_01701603.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli B], gi... gi\|75227494, gi\|... - gi\|75227494\|ref\|ZP_00714258.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase... gi\|75257307, gi\|... - gi\|75257307\|ref\|ZP_00728831.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase... gi\|169754144, gi... - gi\|170019216\|ref\|YP_001724170.1\| phosphoribosylglycinamide formyltransferase [Escherichia coli ATCC ... gi\|83570719, gi\|... - gi\|83570719\|ref\|ZP_00922162.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase... gi\|194437618, gi... - gi\|83586851\|ref\|ZP_00925482.1\| COG0299: Folate-dependent phosphoribosylglycinamide formyltransferase...	240.0	[0..1]	[212..1]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIVVLISGN GSNLQAIIDA CKTNKIKGTV RAVFSNKADA FGLERARQAG IATHTLIASA  60
   61 FDSREAYDRE LIHEIDMYAP DVVVLAGFMR ILSPAFVSHY AGRLLNIHPS LLPKYPGLHT 120
  121 HRQALENGDE EHGTSVHFVT DELDGGPVIL QAKVPVFAGD SEDDITARVQ TQEHAIYPLV 180
  181 ISWFADGRLK MHENAAWLDG QRLPPQGYAA DE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	63.154902
Match:	1c2tA
Description:	Glycinamide ribonucleotide transformylase, GART
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.09881190860822	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.01667310557403	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	3.81159871979977	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	3.49010887242285	bayes_pls_golite062009
phosphoribosylglycinamide formyltransferase activity	2.94311083909314	bayes_pls_golite062009
methionyl-tRNA formyltransferase activity	2.39150724300118	bayes_pls_golite062009
catalytic activity	2.16003793103722	bayes_pls_golite062009
binding	1.1813924954238	bayes_pls_golite062009
transferase activity	1.01502594768782	bayes_pls_golite062009
ligase activity	0.922788719307786	bayes_pls_golite062009
formyltetrahydrofolate deformylase activity	0.85803295611657	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: