YRC Public Data Repository - Protein Structure Prediction

Protein:	RISB_GEOSL
Organism:	Geobacter sulfurreducens
Length:	155 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RISB_GEOSL.

Description	E-value	Query Range	Subject Range
gi\|126699303, gi... - gi\|126699303\|ref\|YP_001088200.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synt... gi\|255100828 - gi\|255100828\|ref\|ZP_05329805.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|255306717 - gi\|255306717\|ref\|ZP_05350888.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth...	235.0	[0..4]	[154..2]
gi\|255314462 - gi\|255314462\|ref\|ZP_05356045.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|255517139 - gi\|255517139\|ref\|ZP_05384815.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|255650244 - gi\|255650244\|ref\|ZP_05397146.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|254975333 - gi\|254975333\|ref\|ZP_05271805.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|255092724 - gi\|255092724\|ref\|ZP_05322202.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|145954563, gi... - gi\|90574741\|ref\|ZP_01231233.1\| hypothetical protein CdifQ_02001808 [Clostridium difficile QCD-32g58]...	235.0	[0..4]	[154..2]
RISB_CALS8 - 6,7-dimethyl-8-ribityllumazine synthase OS=Caldicellulosiruptor saccharolyticus (strain ATCC 43494 /...	232.0	[0..2]	[154..1]
gi\|255270243, gi... - gi\|255339106\|ref\|ZP_05379952.1\| 6,7-dimethyl-8-ribityllumazine synthase [Thermoanaerobacter mathrani... gi\|242232021, gi... - gi\|242256428\|ref\|ZP_04801319.1\| 6,7-dimethyl-8-ribityllumazine synthase [Thermoanaerobacter sp. X513... RISB_THEPX - 6,7-dimethyl-8-ribityllumazine synthase OS=Thermoanaerobacter sp. (strain X514) GN=ribH PE=3 SV=1	232.0	[0..2]	[155..1]
RISB_CLOB8 - 6,7-dimethyl-8-ribityllumazine synthase OS=Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)...	232.0	[0..2]	[154..1]
RISB_THEP3 - 6,7-dimethyl-8-ribityllumazine synthase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / ... gi\|241903097, gi... - gi\|241903097\|ref\|ZP_04787825.1\| 6,7-dimethyl-8-ribityllumazine synthase [Thermoanaerobacter brockii ...	231.0	[0..2]	[155..1]
RISB_DESRM - 6,7-dimethyl-8-ribityllumazine synthase OS=Desulfotomaculum reducens (strain MI-1) GN=ribH PE=3 SV=1	229.0	[0..1]	[154..1]
RISB_CLOAB - 6,7-dimethyl-8-ribityllumazine synthase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / J... RISB_CLOAB - 6,7-dimethyl-8-ribityllumazine synthase OS=Clostridium acetobutylicum GN=ribH PE=3 SV=1	227.0	[0..2]	[154..1]
RISB_BACSK - 6,7-dimethyl-8-ribityllumazine synthase OS=Bacillus clausii (strain KSM-K16) GN=ribH PE=3 SV=1	227.0	[0..1]	[153..1]
RISB_SYNFM - 6,7-dimethyl-8-ribityllumazine synthase OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN...	227.0	[0..2]	[154..1]

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Predicted Domain #1

Region A:
Residues: [1-155]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRFIEGKLD ATGLRFGIIV SRFNSFIGER LLEGALDALV RHGGDDGDID VVRVPGAFEI  60
   61 PLTAQKLVQK GNYDAVICLG AVIRGSTPHF DYVAAEVSKG IAHVSLATGV PVVFGVLTTD 120
  121 TIEQAIERAG TKAGNKGFDA AVTAIETARL YRELR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.0
Match:	1rvvA
Description:	Lumazine synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
6,7-dimethyl-8-ribityllumazine synthase activity	5.61825642183907	bayes_pls_golite062009
intramolecular transferase activity, transferring acyl groups	4.02275160603209	bayes_pls_golite062009
catalytic activity	1.78070169551865	bayes_pls_golite062009
riboflavin synthase activity	1.72639804812167	bayes_pls_golite062009
isomerase activity	0.268840799327499	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: