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View Structure Prediction Details

Protein: RNPA_STRP8
Organism: Streptococcus pyogenes MGAS8232
Length: 119 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNPA_STRP8.

Description E-value Query
Range
Subject
Range
RNPA_STRPC - Ribonuclease P protein component OS=Streptococcus pyogenes serotype M12 (strain MGAS9429) GN=rnpA PE...
RNPA_STRPB - Ribonuclease P protein component OS=Streptococcus pyogenes serotype M12 (strain MGAS2096) GN=rnpA PE...
127.0 [0..1] [119..1]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKTYRVKRE KDFQAIFKDG KSTANRKFVI YHLNRGQDHF RVGISVGKKI GNAVTRNAVK  60
   61 RKIRHVIMAL GHQLKSEDFV VIARKGVESL EYQELQQNLH HVLKLAQLLE KGFESEEKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 1d6tA
Description: RNase P protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
tRNA-specific ribonuclease activity 6.1454778021122 bayes_pls_golite062009
ribonuclease P activity 5.34408239201797 bayes_pls_golite062009
structural constituent of ribosome 3.49304472389303 bayes_pls_golite062009
RNA binding 2.94550290381601 bayes_pls_golite062009
structural molecule activity 2.91017901273919 bayes_pls_golite062009
3'-5'-exoribonuclease activity 2.16830676862423 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.94887328847363 bayes_pls_golite062009
exoribonuclease activity 1.90081280972069 bayes_pls_golite062009
mRNA binding 1.42024615739664 bayes_pls_golite062009
ribonuclease activity 1.31550811238109 bayes_pls_golite062009
transcription regulator activity 1.20748032530392 bayes_pls_golite062009
nucleic acid binding 1.05662964529454 bayes_pls_golite062009
binding 0.907487229190259 bayes_pls_golite062009
catalytic activity 0.878454819018611 bayes_pls_golite062009
DNA binding 0.828609700556836 bayes_pls_golite062009
nuclease activity 0.69721312877891 bayes_pls_golite062009
3'-5' exonuclease activity 0.477960254167 bayes_pls_golite062009

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