YRC Public Data Repository - Protein Structure Prediction

Protein:	RRAA_ECOLI
Organism:	Escherichia coli
Length:	161 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRAA_ECOLI.

Description	E-value	Query Range	Subject Range
RRAAH_PSEPF - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas fluorescens (strain Pf0-1) GN=Pfl...	214.0	[0..2]	[158..3]
RRAAH_PSEU2 - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas syringae pv. syringae (strain B72...	213.0	[0..1]	[160..1]
RRAAH_AZOVD - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-... gi\|53611078, gi\|... - gi\|67153424\|ref\|ZP_00415169.1\| Protein of unknown function 1935 [Azotobacter vinelandii AvOP], ref\|Z...	212.0	[0..1]	[158..1]
RRAAH_PSESM - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas syringae pv. tomato (strain DC300... RRAA_PSESM - Regulator of ribonuclease activity A OS=Pseudomonas syringae pv. tomato GN=rraA PE=3 SV=1 gi\|213968091, gi... - gi\|213968091\|ref\|ZP_03396236.1\| dimethylmenaquinone methyltransferase family protein [Pseudomonas sy...	209.0	[0..1]	[160..1]
RRAAH_HAHCH - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Hahella chejuensis (strain KCTC 2396) GN=HCH_...	209.0	[0..1]	[160..1]
RRAAH_PSEF5 - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas fluorescens (strain Pf-5 / ATCC B...	209.0	[0..2]	[158..3]
RRAAH_PSEAB - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN... RRAA_PSEAE - Regulator of ribonuclease activity A OS=Pseudomonas aeruginosa GN=rraA PE=1 SV=1 RRAAH_PSEAE - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas aeruginosa (strain ATCC 15692 / P... gi\|254240114, gi... - gi\|84328093\|ref\|ZP_00976104.1\| COG0684: Demethylmenaquinone methyltransferase [Pseudomonas aeruginos... RRAAH_PSEA8 - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas aeruginosa (strain LESB58) GN=PLE... gi\|194545851, gi... - gi\|84321505\|ref\|ZP_00969862.1\| COG0684: Demethylmenaquinone methyltransferase [Pseudomonas aeruginos...	208.0	[0..1]	[158..1]
gi\|107101203 - gi\|107101203\|ref\|ZP_01365121.1\| hypothetical protein PaerPA_01002235 [Pseudomonas aeruginosa PACS2]	206.0	[0..1]	[158..1]
RRAAH_PSEPK - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas putida (strain KT2440) GN=PP_2084...	206.0	[0..2]	[158..3]
RRAAH_PSEA7 - Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase OS=Pseudomonas aeruginosa (strain PA7) GN=PSPA7_...	205.0	[0..1]	[160..1]

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Predicted Domain #1

Region A:
Residues: [1-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYDTSELCD IYQEDVNVVE PLFSNFGGRA SFGGQIITVK CFEDNGLLYD LLEQNGRGRV  60
   61 LVVDGGGSVR RALVDAELAR LAVQNEWEGL VIYGAVRQVD DLEELDIGIQ AMAAIPVGAA 120
  121 GEGIGESDVR VNFGGVTFFS GDHLYADNTG IILSEDPLDI E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.69897
Match:	1q5xA
Description:	STRUCTURE OF RRAA (MENG), A PROTEIN INHIBITOR OF RNA PROCESSING
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.812797739319617	bayes_pls_golite062009
binding	0.398946779962706	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: