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View Structure Prediction Details

Protein: CCL2_RABIT
Organism: Oryctolagus cuniculus
Length: 125 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCL2_RABIT.

Description E-value Query
Range
Subject
Range
gi|164665382, gi... - gi|57527998|ref|NP_001009579.1| chemokine (C-C motif) ligand 3-like 1 [Sus scrofa], gi|49354682|gb|A...
115.0 [0..1] [91..1]
gi|55531 - gi|55531|emb|CAA34901.1| JE product [Rattus sp.]
CCL2_RAT - C-C motif chemokine 2 OS=Rattus norvegicus GN=Ccl2 PE=2 SV=1
114.0 [0..1] [124..1]
gi|6531363 - gi|6531363|gb|AAF15379.1|AF065929_1 small inducible cytokine A2 precursor [Mus musculus]
114.0 [0..1] [124..1]
CCL4_MACMU - C-C motif chemokine 4 OS=Macaca mulatta GN=CCL4 PE=2 SV=1
112.0 [0..1] [91..1]
CCL4_BOVIN - C-C motif chemokine 4 OS=Bos taurus GN=CCL4 PE=3 SV=1
112.0 [0..1] [91..1]
gi|21070221, gi|... - gi|21070221|gb|AAM34214.1|AF506972_1 mcp-2 [Equus caballus], gi|126352332|ref|NP_001075333.1| mcp-2 ...
111.0 [0..1] [99..1]
gi|28894125 - gi|28894125|gb|AAO52735.1| monocyte chemoattractant protein-3 [Macaca nemestrina]
111.0 [0..2] [98..12]

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Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVSATLLCL LLIAVAFSSH VLAQPDAVNS PVTCCYTFTN KTISVKRLMS YRRINSTKCP  60
   61 KEAVIFMTKL AKGICADPKQ KWVQDAIANL DKKMQTPKTL TSYSTTQEHT TNLSSTRTPS 120
  121 TTTSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 1bo0A
Description: MONOCYTE CHEMOATTRACTANT PROTEIN-3, NMR, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytokine activity 8.07273475133641 bayes_pls_golite062009
chemokine receptor binding 7.19574940007631 bayes_pls_golite062009
chemokine activity 7.19574940007631 bayes_pls_golite062009
G-protein-coupled receptor binding 7.12866319987718 bayes_pls_golite062009
receptor binding 5.70505228637425 bayes_pls_golite062009
protein binding 3.96178206863622 bayes_pls_golite062009
interleukin-8 receptor binding 3.86135397575984 bayes_pls_golite062009
binding 3.44333267537536 bayes_pls_golite062009
chemoattractant activity 3.05299139114464 bayes_pls_golite062009
heparin binding 2.48790323783525 bayes_pls_golite062009
glycosaminoglycan binding 1.80091312295242 bayes_pls_golite062009
CCR2 chemokine receptor binding 1.78317158345185 bayes_pls_golite062009
polysaccharide binding 1.28416986663426 bayes_pls_golite062009
protein kinase activity 1.20167556785693 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.09332950161087 bayes_pls_golite062009
kinase activity 1.04394246442162 bayes_pls_golite062009
pattern binding 1.02739535268516 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.0107537553708 bayes_pls_golite062009
CCR chemokine receptor binding 0.697359799598971 bayes_pls_golite062009
signal transducer activity 0.26342831190617 bayes_pls_golite062009
molecular transducer activity 0.26342831190617 bayes_pls_golite062009
carbohydrate binding 0.14673741350408 bayes_pls_golite062009
catalytic activity 0.11400259673574 bayes_pls_golite062009
transporter activity 0.0541029584618528 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0194812295164102 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle