YRC Public Data Repository - Protein Structure Prediction

Protein:	GLUQ_ECOLI, YADB...
Organism:	Escherichia coli
Length:	298 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLUQ_ECOLI, YADB....

Description	E-value	Query Range	Subject Range
SYE_PELPD - Glutamate--tRNA ligase OS=Pelobacter propionicus (strain DSM 2379) GN=gltX PE=3 SV=1	334.0	[0..6]	[295..4]
gi\|221135038 - gi\|221135038\|ref\|ZP_03561341.1\| glutamyl-tRNA synthetase [Glaciecola sp. HTCC2999] gi\|114773017, gi... - gi\|114773017\|ref\|ZP_01450312.1\| glutamyl-tRNA synthetase [alpha proteobacterium HTCC2255], gi\|114546... gi\|114773017 - gi\|114773017\|ref\|ZP_01450312.1\| glutamyl-tRNA synthetase [alpha proteobacterium HTCC2255]	329.0	[0..6]	[295..3]
SYE_GEOSL - Glutamyl-tRNA synthetase OS=Geobacter sulfurreducens GN=gltX PE=3 SV=1 SYE_GEOSL - Glutamate--tRNA ligase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=gltX PE=...	328.0	[0..6]	[295..4]
gi\|110548321, gi... - gi\|222056003\|ref\|YP_002538365.1\| glutamyl-tRNA synthetase [Geobacter sp. FRC-32], gi\|221565292\|gb\|AC...	327.0	[0..4]	[295..2]
SYE_GEOUR - Glutamate--tRNA ligase OS=Geobacter uraniireducens (strain Rf4) GN=gltX PE=3 SV=1	327.0	[0..5]	[295..3]
SYE_NITMU - Glutamate--tRNA ligase OS=Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) GN=gltX PE=3 SV...	327.0	[0..6]	[295..2]
SYE_GEOMG - Glutamate--tRNA ligase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) GN=gltX P...	326.0	[0..6]	[295..4]
gi\|85693701, gi\|... - gi\|85712423\|ref\|ZP_01043472.1\| glutamyl-tRNA synthetase [Idiomarina baltica OS145], gi\|85693701\|gb\|E...	326.0	[0..6]	[295..3]
SYE_CARHZ - Glutamate--tRNA ligase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901...	326.0	[0..6]	[295..2]
SYE_NITEU - Glutamate--tRNA ligase OS=Nitrosomonas europaea GN=gltX PE=3 SV=1 SYE_NITEU - Glutamate--tRNA ligase OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=gltX PE=3 SV=1	325.0	[0..6]	[296..2]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDTQYIGRF APSPSGELHF GSLIAALGSY LQARARQGRW LVRIEDIDPP REVPGAAETI  60
   61 LRQLEHYGLH WDGDVLWQSQ RHDAYREALA WLHEQGLSYY CTCTRARIQS IGGIYDGHCR 120
  121 VLHHGPDNAA VRIRQQHPVT QFTDQLRGII HADEKLARED FIIHRRDGLF AYNLAVVVDD 180
  181 HFQGVTEIVR GADLIEPTVR QISLYQLFGW KVPDYIHLPL ALNPQGAKLS KQNHAPALPK 240
  241 GDPRPVLIAA LQFLGQQAEA HWQDFSVEQI LQSAVKNWRL TAVPESAIVN STFSNASC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.69897
Match:	1nzjA
Description:	Crystal Structure and Activity Studies of Escherichia Coli Yadb ORF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	6.4693800838561	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	6.4693800838561	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	6.4443227172352	bayes_pls_golite062009
ligase activity	5.65872852832815	bayes_pls_golite062009
catalytic activity	2.74718220535323	bayes_pls_golite062009
glutamate-tRNA ligase activity	1.69027214128932	bayes_pls_golite062009
methionine-tRNA ligase activity	1.63830426964771	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.51606758855865	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.33068350385001	bayes_pls_golite062009
cysteine-tRNA ligase activity	1.02341432978103	bayes_pls_golite062009
arginine-tRNA ligase activity	0.92755725518345	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.64528548803763	bayes_pls_golite062009
transferase activity	0.565342623537184	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: