YRC Public Data Repository - Protein Structure Prediction

Protein:	YDDQ_ECOLI
Organism:	Escherichia coli
Length:	298 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDDQ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|150390667, gi... - gi\|77683645\|ref\|ZP_00799091.1\| Binding-protein-dependent transport systems inner membrane component ...	250.0	[0..2]	[294..11]
DPPC_BACPE - Dipeptide transport system permease protein DppC OS=Bacillus pseudofirmus (strain OF4) GN=dppC PE=3 ... gi\|11277274, gi\|... - gi\|1813497\|gb\|AAB41690.1\| dipeptide transporter protein DppC [Bacillus firmus], pir\|\|T44637 dipeptid... DPPC_BACPF - Dipeptide transport system permease protein dppC OS=Bacillus pseudofirmus GN=dppC PE=3 SV=1	243.0	[0..1]	[294..10]
gi\|158140582, gi... - gi\|158320383\|ref\|YP_001512890.1\| binding-protein-dependent transport systems inner membrane componen...	243.0	[0..17]	[294..25]
gi\|10172642, gi\|... - gi\|15612593\|ref\|NP_240896.1\| oligopeptide ABC transporter (permease) [Bacillus halodurans C-125], gi... gi\|25296705 - pir\|\|F83653 oligopeptide ABC transporter (permease) BH0030 [imported] - Bacillus halodurans (strain ...	243.0	[0..2]	[294..8]
gi\|134052991, gi... - gi\|88945336\|ref\|ZP_01148513.1\| oligopeptide ABC transporter permease [Desulfotomaculum reducens MI-1...	242.0	[0..3]	[295..4]
gi\|56378846, gi\|... - gi\|56419004\|ref\|YP_146322.1\| dipeptide ABC transporter (permease) [Geobacillus kaustophilus HTA426],...	241.0	[0..3]	[294..7]
gi\|23100522, gi\|... - gi\|23100522\|ref\|NP_693989.1\| oligopeptide ABC transporter permease [Oceanobacillus iheyensis HTE831]...	238.0	[0..4]	[294..9]
gi\|110620064, gi... - gi\|147921516\|ref\|YP_684668.1\| putative ABC-type peptide transport system, permease component 2 [uncu...	235.0	[0..24]	[295..37]
gi\|89087265, gi\|... - gi\|89098102\|ref\|ZP_01170988.1\| oligopeptide ABC transporter (permease) [Bacillus sp. NRRL B-14911], ...	234.0	[0..4]	[295..14]

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Predicted Domain #1

Region A:
Residues: [1-79]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLSEETSAV RPQKQTRFNG AKLVWMLKGS PLTVTSAVII VLMLLMMIFS PWLATHDPNA  60
   61 IDLTARLLPP SAAHWFGTD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [80-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVGRDLFSRV LVGSQQSILA GLVVVAIAGM IGSLLGCLSG VLGGRADAII MRIMDIMLSI  60
   61 PSLVLTMALA AALGPSLFNA MLAIAIVRIP FYVRLARGQA LVVRQYTYVQ AAKTFGASRW 120
  121 HLINWHILRN SLPPLIVQAS LDIGSAILMA ATLGFIGLGA QQPSAEWGAM VANGRNYVLD 180
  181 QWWYCAFPGA AILLTAVGFN LFGDGIRDLL DPKAGGKQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.045757
Match:	2onkC
Description:	No description for 2onkC was found.

Predicted functions:

Term	Confidence	Notes
ATPase activity, coupled to transmembrane movement of substances	7.98776119907207	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	7.98726234902655	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	7.98726234902655	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	7.97287417765536	bayes_pls_golite062009
primary active transmembrane transporter activity	7.96249144456164	bayes_pls_golite062009
active transmembrane transporter activity	7.8678894318504	bayes_pls_golite062009
ATPase activity, coupled	7.29227234008448	bayes_pls_golite062009
ATPase activity	6.94069583578738	bayes_pls_golite062009
nucleoside-triphosphatase activity	6.59903874016214	bayes_pls_golite062009
pyrophosphatase activity	6.52169210550643	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	6.50067149801529	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	6.5003333073452	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.78398318541319	bayes_pls_golite062009
ion transmembrane transporter activity	5.07829337366931	bayes_pls_golite062009
hydrolase activity	4.78607811092587	bayes_pls_golite062009
transporter activity	4.47791794099048	bayes_pls_golite062009
transmembrane transporter activity	4.39634414867723	bayes_pls_golite062009
cation transmembrane transporter activity	4.35124450289762	bayes_pls_golite062009
substrate-specific transporter activity	3.91409799494188	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	3.2006428628965	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.95360205425391	bayes_pls_golite062009
sugar transmembrane transporter activity	2.67115360425434	bayes_pls_golite062009
iron ion transmembrane transporter activity	2.58662753282402	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	2.56867883684303	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	2.42763030383098	bayes_pls_golite062009
maltose-transporting ATPase activity	2.14010989459818	bayes_pls_golite062009
oligosaccharide-transporting ATPase activity	2.14010989459818	bayes_pls_golite062009
oligosaccharide transmembrane transporter activity	2.14010989459818	bayes_pls_golite062009
maltose transmembrane transporter activity	2.09224118357857	bayes_pls_golite062009
alpha-glucoside transmembrane transporter activity	2.09224118357857	bayes_pls_golite062009
disaccharide transmembrane transporter activity	2.09224118357857	bayes_pls_golite062009
glucoside transmembrane transporter activity	2.04706530621258	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.92041789093512	bayes_pls_golite062009
anion transmembrane transporter activity	1.81715503217512	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	1.79613658743425	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	1.74937989644368	bayes_pls_golite062009
secondary active transmembrane transporter activity	0.96228415837358	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.798639167073698	bayes_pls_golite062009
sulfate transmembrane transporter activity	0.72950761930647	bayes_pls_golite062009
symporter activity	0.483541714040201	bayes_pls_golite062009
solute:cation symporter activity	0.483541714040201	bayes_pls_golite062009
catalytic activity	0.427775057748038	bayes_pls_golite062009
maltooligosaccharide-importing ATPase activity	0.16532450344344	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	0.0202682073710961	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: