YRC Public Data Repository - Protein Structure Prediction

Protein:	YRAO_ECOLI, DIAA...
Organism:	Escherichia coli
Length:	196 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRAO_ECOLI, DIAA....

Description	E-value	Query Range	Subject Range
SO0298 - phosphoheptose isomerase GMHA_SHESM - Phosphoheptose isomerase OS=Shewanella sp. (strain MR-4) GN=gmhA PE=3 SV=1 GMHA_SHESA - Phosphoheptose isomerase OS=Shewanella sp. (strain ANA-3) GN=gmhA PE=3 SV=1 GMHA_SHESR - Phosphoheptose isomerase OS=Shewanella sp. (strain MR-7) GN=gmhA PE=3 SV=1 GMHA_SHEON - Phosphoheptose isomerase OS=Shewanella oneidensis (strain MR-1) GN=gmhA PE=3 SV=1	191.0	[0..1]	[195..1]
GMHA_SHEAM - Phosphoheptose isomerase OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=gmhA PE=3 SV=1	191.0	[0..1]	[196..1]
GMHA_SHEB9 - Phosphoheptose isomerase OS=Shewanella baltica (strain OS195) GN=gmhA PE=3 SV=1 GMHA_SHEB8 - Phosphoheptose isomerase OS=Shewanella baltica (strain OS185) GN=gmhA PE=3 SV=1 GMHA_SHEB2 - Phosphoheptose isomerase OS=Shewanella baltica (strain OS223) GN=gmhA PE=3 SV=1 GMHA_SHEB5 - Phosphoheptose isomerase OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=gmhA PE=3 SV=1	191.0	[0..1]	[195..1]
GMHA_SHELP - Phosphoheptose isomerase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=gmhA PE=3 SV=1	190.0	[0..1]	[195..1]
GMHA_SHESW - Phosphoheptose isomerase OS=Shewanella sp. (strain W3-18-1) GN=gmhA PE=3 SV=1 GMHA_SHEPC - Phosphoheptose isomerase OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=gmhA PE=3 SV=1 gi\|124508423, gi... - gi\|124548491\|ref\|ZP_01707132.1\| phosphoheptose isomerase [Shewanella putrefaciens 200], gi\|124508423...	190.0	[0..1]	[195..1]
GMHA_SHEFN - Phosphoheptose isomerase OS=Shewanella frigidimarina (strain NCIMB 400) GN=gmhA PE=3 SV=1	189.0	[0..1]	[195..1]
GMHA_SHEDO - Phosphoheptose isomerase OS=Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) GN=g...	189.0	[0..1]	[195..1]
gi\|56554409, gi\|... - gi\|56554409\|pdb\|1X92\|B Chain B, Crystal Structure Of Pseudomonas Aeruginosa Phosphoheptose Isomerase...	187.0	[0..1]	[195..5]
gi\|94425963, gi\|... - gi\|94501910\|ref\|ZP_01308420.1\| phosphoheptose isomerase [Oceanobacter sp. RED65], gi\|94425963\|gb\|EAT...	186.0	[0..2]	[196..4]
gi\|126170843, gi... - gi\|84317022\|ref\|ZP_00965479.1\| COG0279: Phosphoheptose isomerase [Pseudomonas aeruginosa C3719], gi\|... gi\|107099990 - gi\|107099990\|ref\|ZP_01363908.1\| hypothetical protein PaerPA_01001011 [Pseudomonas aeruginosa PACS2] GMHA_PSEAB - Phosphoheptose isomerase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=gmhA PE=1 SV=1 gi\|126198142, gi... - gi\|84323043\|ref\|ZP_00971120.1\| COG0279: Phosphoheptose isomerase [Pseudomonas aeruginosa 2192], gi\|2... GMHA_PSEAE - Phosphoheptose isomerase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12... GMHA_PSEA8 - Phosphoheptose isomerase OS=Pseudomonas aeruginosa (strain LESB58) GN=gmhA PE=3 SV=1 GMHA_PSEAE - Phosphoheptose isomerase OS=Pseudomonas aeruginosa GN=gmhA PE=1 SV=1	186.0	[0..1]	[195..3]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQERIKACFT ESIQTQIAAA EALPDAISRA AMTLVQSLLN GNKILCCGNG TSAANAQHFA  60
   61 ASMINRFETE RPSLPAIALN TDNVVLTAIA NDRLHDEVYA KQVRALGHAG DVLLAISTRG 120
  121 NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGPQDVE IRIPSHRSAR IQEMHMLTVN 180
  181 CLCDLIDNTL FPHQDD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.69897
Match:	1x92A
Description:	CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PHOSPHOHEPTOSE ISOMERASE IN COMPLEX WITH REACTION PRODUCT D-GLYCERO-D-MANNOPYRANOSE-7-PHOSPHATE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
D-sedoheptulose 7-phosphate isomerase activity	4.14215058629352	bayes_pls_golite062009
catalytic activity	1.5278037255884	bayes_pls_golite062009
glucose-6-phosphate isomerase activity	1.27102475335512	bayes_pls_golite062009
glutamine-fructose-6-phosphate transaminase (isomerizing) activity	1.11549102314657	bayes_pls_golite062009
isomerase activity	0.875614547872629	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	0.718035369881213	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.543772038478781	bayes_pls_golite062009
binding	0.239170972934454	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: