YRC Public Data Repository - Protein Structure Prediction

Protein:	MDP1
Organism:	Homo sapiens
Length:	176 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDP1.

Description	E-value	Query Range	Subject Range
MGDP1_MOUSE - Magnesium-dependent phosphatase 1 OS=Mus musculus GN=Mdp1 PE=1 SV=1	2.0E-31	[1..164]	[1..164]
gi\|73962658 - gi\|73962658\|ref\|XP_537388.2\| PREDICTED: similar to magnesium-dependent phosphatase-1 [Canis familiar...	6.0E-31	[1..162]	[54..215]
gi\|149063990, gi... - gi\|27700106\|ref\|XP_214200.1\| PREDICTED: similar to magnesium-dependent phosphatase-1 [Rattus norvegi...	2.0E-30	[1..164]	[1..164]
gi\|112822365, gi... - gi\|113460322\|ref\|YP_718383.1\| phosphoglycolate phosphatase [Haemophilus somnus 129PT], gi\|112822365\|...	1.0E-28	[1..163]	[1..222]
gi\|170718574, gi... - gi\|53728307\|ref\|ZP_00348122.1\| COG0546: Predicted phosphatases [Haemophilus somnus 2336], gi\|1707185...	1.0E-28	[1..163]	[1..222]
gi\|88790279, gi\|... - gi\|88812493\|ref\|ZP_01127742.1\| 2-phosphoglycolate phosphatase [Nitrococcus mobilis Nb-231], gi\|88790...	2.0E-28	[1..171]	[1..227]
gi\|32034240 - gi\|32034240\|ref\|ZP_00134451.1\| COG0546: Predicted phosphatases [Actinobacillus pleuropneumoniae sero... gi\|126098145, gi... - gi\|126209353\|ref\|YP_001054578.1\| phosphoglycolate phosphatase [Actinobacillus pleuropneumoniae L20],...	4.0E-28	[1..147]	[1..197]
gi\|229811380, gi... - gi\|229845694\|ref\|ZP_04465817.1\| phosphoglycolate phosphatase [Haemophilus influenzae 6P18H1], gi\|229... gi\|144985848, gi... - gi\|145633479\|ref\|ZP_01789208.1\| phosphoglycolate phosphatase [Haemophilus influenzae 3655], gi\|14498... GPH_HAEI8 - Phosphoglycolate phosphatase OS=Haemophilus influenzae (strain 86-028NP) GN=NTHI0697 PE=3 SV=1	6.0E-28	[1..164]	[1..224]
gi\|145272121, gi... - gi\|145638526\|ref\|ZP_01794135.1\| phosphoglycolate phosphatase [Haemophilus influenzae PittII], gi\|145... gi\|53733330 - gi\|53733330\|ref\|ZP_00156383.2\| COG0546: Predicted phosphatases [Haemophilus influenzae R2866]	3.0E-27	[1..164]	[1..224]

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Predicted Domain #1

Region A:
Residues: [1-176]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARLPKLAVF DLDYTLWPFW VDTHVDPPFH KSSDGTVRDR RGQDVRLYPE VPEVLKRLQS  60
   61 LGVPGAAASR TSEIEGANQL LELFDLFRYF VHREIYPGSK ITHFERLQQK TGIPFSQMIF 120
  121 FDDERRNIVD VSKLGVTCIH IQNGMNLQTL SQGLETFAKA QTGPLRSSLE ESPFEA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.0
Match:	1u7oA
Description:	Magnesium Dependent Phosphatase 1 (MDP-1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	0.877696725573375	bayes_pls_golite062009
catalytic activity	0.786540433906087	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: