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View Structure Prediction Details

Protein: gi|41349446
Organism: Homo sapiens
Length: 833 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|41349446.

Description E-value Query
Range
Subject
Range
gi|114593426 - gi|114593426|ref|XP_001166908.1| PREDICTED: stromal interaction molecule 2 isoform 3 [Pan troglodyte...
0.0 [1..833] [1..833]
gi|109073940 - gi|109073940|ref|XP_001084785.1| PREDICTED: stromal interaction molecule 2 isoform 3 [Macaca mulatta...
0.0 [1..816] [1..815]
gi|7959225 - gi|7959225|dbj|BAA96006.1| KIAA1482 protein [Homo sapiens]
0.0 [16..833] [1..818]
gi|109499717, gi... - gi|157787187|ref|NP_001099220.1| stromal interaction molecule 2 [Rattus norvegicus], gi|149047197|gb...
0.0 [1..833] [1..809]
gi|187950829, gi... - gi|82897407|ref|XP_905393.1| PREDICTED: stromal interaction molecule 2 isoform 3 [Mus musculus], gi|...
0.0 [14..833] [13..812]

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Predicted Domain #1
Region A:
Residues: [1-124]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAAGIRAPE AAGADGTRLA PGGSPCLRRR GRPEESPAAV VAPRGAGELQ AAGAPLRFHP  60
   61 ASPRRLHPAS TPGPAWGWLL RRRRWAALLV LGLLVAGAAD GCELVPRHLR GRRATGSAAT 120
  121 AASS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [125-431]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAAAAGDSPA LMTDPCMSLS PPCFTEEDRF SLEALQTIHK QMDDDKDGGI EVEESDEFIR  60
   61 EDMKYKDATN KHSHLHREDK HITIEDLWKR WKTSEVHNWT LEDTLQWLIE FVELPQYEKN 120
  121 FRDNNVKGTT LPRIAVHEPS FMISQLKISD RSHRQKLQLK ALDVVLFGPL TRPPHNWMKD 180
  181 FILTVSIVIG VGGCWFAYTQ NKTSKEHVAK MMKDLESLQT AEQSLMDLQE RLEKAQEENR 240
  241 NVAVEKQNLE RKMMDEINYA KEEACRLREL REGAECELSR RQYAEQELEQ VRMALKKAEK 300
  301 EFELRSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [432-575]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WSVPDALQKW LQLTHEVEVQ YYNIKRQNAE MQLAIAKDEA EKIKKKRSTV FGTLHVAHSS  60
   61 SLDEVDHKIL EAKKALSELT TCLRERLFRW QQIEKICGFQ IAHNSGLPSL TSSLYSDHSW 120
  121 VVMPRVSIPP YPIAGGVDDL DEDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 2iw5A
Description: No description for 2iw5A was found.

Predicted Domain #4
Region A:
Residues: [576-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPIVSQFPGT MAKPPGSLAR SSSLCRSRRS IVPSSPQPQR AQLAPHAPH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [625-833]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSHPRHPHHP QHTPHSLPSP DPDILSVSSC PALYRNEEEE EAIYFSAEKQ WEVPDTASEC  60
   61 DSLNSSIGRK QSPPLSLEIY QTLSPRKISR DEVSLEDSSR GDSPVTVDVS WGSPDCVGLT 120
  121 ETKSMIFSPA SKVYNGILEK SCSMNQLSSG IPVPKPRHTS CSSAGNDSKP VQEAPSVARI 180
  181 SSIPHDLCHN GEKSKKPSKI KSLFKKKSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle