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View Structure Prediction Details

Protein: gi|45551962, gi|...
Organism: Drosophila melanogaster
Length: 623 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|45551962, gi|....

Description E-value Query
Range
Subject
Range
ASH2L_MOUSE - Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Mus musculus GN=Ash2l PE=1 SV=1
317.0 [0..20] [618..16]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGIYIYTIT IEARARVGAK RQGQGCQAVC SKCCRLSFIA LWRRSGICKR TMCLPANGHS  60
   61 GQPPNFLRAD SQMDTSSPTE SSSEVNF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-246]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAEEDKSQET RSAAGVCYCG KERNLNIVEL LCATCSRWVH ETCVSYQLGK GKLLPFITNY  60
   61 VFVCKNCSAS GLESFRKSQA TISQMCHCAI ANMQQAASRD GRRQIQFSKD KEIIPYIEQY 120
  121 WEAMTTMPRR LTQSWYSTVQ RSLVKDVQTL FTYEEHAEH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.522879
Match: 2f6jA
Description: No description for 2f6jA was found.

Predicted Domain #3
Region A:
Residues: [247-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAMYGLFHQD LRIIKPNYES MSKSGALRLT DDGYTQASLS KNNRQKRKFP GTDSGPTGKK  60
   61 GRPSSDITAN VKLPPHGYPL EHPFNKDGYR YILAEPDPHA PFRQEFDESS DWAGKPIPGW 120
  121 LYRIL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [372-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPHSVLLALH DRAPQLKISE DRLAVTGERG YCMVRATHSV NRGCWYFEVT IEEMPDGAAT  60
   61 RLGWGREYGN LQAPLGYDKF GYSWRSRKGT KFTESHGKHY SDAYVEGDTL GFLIELPEEA 120
  121 SLDYLPNTFK DRPLVKFKSH LYYEDKDKIT ETLKNLHILQ GSRIEFFKNG QSQGVAFEDI 180
  181 YAGSYFPAIS IHKSATVSVN FGPAFKYPEV LVEHKAKGMH DRVEELITEQ CLADTLYLTE 240
  241 HDGRLRLDNM GL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.39794
Match: 2fnjA
Description: No description for 2fnjA was found.

Predicted functions:

Term Confidence Notes
binding 2.40096962515027 bayes_pls_golite062009
transcription regulator activity 2.15398264148864 bayes_pls_golite062009
nucleic acid binding 1.95513305822187 bayes_pls_golite062009
protein binding 1.80794638640093 bayes_pls_golite062009
DNA binding 1.80079581406991 bayes_pls_golite062009
transcription activator activity 1.26528137349343 bayes_pls_golite062009
transcription factor activity 1.15427978494805 bayes_pls_golite062009
structural molecule activity 0.591248843231149 bayes_pls_golite062009
protein kinase activity 0.349782201631236 bayes_pls_golite062009
cytoskeletal protein binding 0.256457488897892 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.145569571363938 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0116447990963908 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle