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View Structure Prediction Details

Protein: par-1-PH
Organism: Drosophila melanogaster
Length: 993 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for par-1-PH.

Description E-value Query
Range
Subject
Range
par-1-PF - The gene par-1 is referred to in FlyBase by the symbol Dmel\par-1 (CG8201, FBgn0260934). It is a pro...
449.0 [0..268] [993..373]

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Predicted Domain #1
Region A:
Residues: [1-109]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQTSSHRQM HHSSNNNNKE EPPQPASQFG NRRTSTRKST SSSKHYPTLV QPLRKDELSL  60
   61 LRDSLLRNGS IMRKNPERRP VTISELKPVN TGQGTSGSVL PITAEDAAG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [110-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSSSSITQLM AFQLPVDRSA KTDDLAAESS ASAAAAVAPK EGRNEFYIVG DGYHRTDHCY  60
   61 YRSPNGDFHK LPSDSFHKMS EGCFVRMADG VFRRLEVPTK AQISRRSSRA EEIGDATSQG 120
  121 NGSAATNVKS QLMRFLKRSK SHTPATIAKL QREKEEARAE RKQRLSNALR QKNLAATNAA 180
  181 SAAAANSSYA SGGGGGTVSS RNNKIVVTMI ENGGLPIVAT SKAERPKAKE SASSSDKARN 240
  241 SRGSPNMQMR SSAPMRWRAT EEHIGKYKLI KTIGKGNFAK VKLAKHLPTG KEVAIKIIDK 300
  301 TQLNPGSLQK LFREVRIMKM LDHPNIVKLF QVIETEKTLY LIMEYASGGE VFDYLVLHGR 360
  361 MKEKEARVKF RQIVSAVQYC HQKRIIHRDL KAENLLLDSE LNIKIADFGF SNEFTPGSKL 420
  421 DTFCGSPPYA APELFQGKKY DGPEVDVWSL GVILYTLVSG SLPFDGSTLR ELRERVLRGK 480
  481 YRIPFYMSTD CENLLRKFLV LNPAKRASLE TIMGDKWMNM GFEEDELK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.221849
Match: 2h8hA
Description: No description for 2h8hA was found.

Predicted functions:

Term Confidence Notes
protein kinase activity 5.4586557943719 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 5.04467222534257 bayes_pls_golite062009
kinase activity 4.85903980916957 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.63692708178478 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
transferase activity 3.26787750561728 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
molecular adaptor activity 1.33740973673697 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
SH3/SH2 adaptor activity 1.2323381312171 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
cytoskeletal protein binding 1.22172815474021 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
protein binding, bridging 0.83823250804321 bayes_pls_golite062009
tubulin binding 0.525721160726465 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
actin binding 0.456340967230669 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
microtubule binding 0.191960933574742 bayes_pls_golite062009
MAP kinase activity 0.08504542461349 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.0556163711947139 bayes_pls_golite062009
transmembrane receptor activity 0.00652065412910241 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [638-729]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYIEPKADLA DPKRIEALVA MGYNRSEIEA SLSQVRYDDV FATYLLLGRK STDPESDGSR  60
   61 SGSSLSLRNI SGNDAGANAG SASVQSPTHR GV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 2qnjA
Description: No description for 2qnjA was found.

Predicted Domain #4
Region A:
Residues: [730-904]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRSISASSTK PSRRASSGAE TLRVGPTNAA ATVAAATGAV GAVNPSNNYN AAGSAADRAS  60
   61 VGSNFKRQNT IDSATIKENT ARLAAQNQRP ASATQKMLTT ADTTLNSPAK PRTATKYDPT 120
  121 NGNRTVSGTS GIIPRRSTTL YEKTSSTEKT NVIPAETNSG SAAPAGKGHT KSASV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [905-993]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSPRPSTDGC VSVSNDPLGT RMASAVKSSR HFPRNVPSRS TFHSGQTRAR NNTALEYSGT  60
   61 SGASGDSSHP GRMSFFSKLS SRFSKRPNQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle