Protein: | lola-PP |
Organism: | Drosophila melanogaster |
Length: | 963 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lola-PP.
Description | E-value | Query Range |
Subject Range |
|
580.0 | [0..293] | [962..104] |
Region A: Residues: [1-196] |
1 11 21 31 41 51 | | | | | | 1 MDDDQQFCLR WNNHQSTLIS VFDTLLENET LVDCTLAAEG KFLKAHKVVL SACSPYFATL 60 61 LQEQYDKHPI FILKDVKYQE LRAMMDYMYR GEVNISQDQL AALLKAAESL QIKGLSDNRT 120 121 GGGVAPKPES SGHHRGGKLS GAYTLEQTKR ARLATGGAMD TSGDVSGSRE GSSSPSRRRR 180 181 KVRRRSMEND AHDNSN |
Detection Method: | |
Confidence: | 33.30103 |
Match: | 1r28A |
Description: | Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
transcription regulator activity | 4.03732153795237 | bayes_pls_golite062009 |
DNA binding | 3.50992893425527 | bayes_pls_golite062009 |
nucleic acid binding | 3.39650042677839 | bayes_pls_golite062009 |
transcription repressor activity | 3.34221155527033 | bayes_pls_golite062009 |
transcription factor activity | 2.77967244868934 | bayes_pls_golite062009 |
binding | 2.73171412378045 | bayes_pls_golite062009 |
protein binding | 2.43603601331034 | bayes_pls_golite062009 |
gated channel activity | 2.31670938272069 | bayes_pls_golite062009 |
cation channel activity | 2.29487032939987 | bayes_pls_golite062009 |
ion channel activity | 2.26817638058015 | bayes_pls_golite062009 |
potassium channel activity | 1.44385468589872 | bayes_pls_golite062009 |
voltage-gated cation channel activity | 1.43775565332764 | bayes_pls_golite062009 |
substrate-specific transporter activity | 1.43014386864286 | bayes_pls_golite062009 |
channel activity | 1.41924822300643 | bayes_pls_golite062009 |
passive transmembrane transporter activity | 1.41924822300643 | bayes_pls_golite062009 |
voltage-gated ion channel activity | 1.41843723045096 | bayes_pls_golite062009 |
substrate-specific channel activity | 1.4152854884651 | bayes_pls_golite062009 |
voltage-gated channel activity | 1.40892835925684 | bayes_pls_golite062009 |
sequence-specific DNA binding | 1.3794923488776 | bayes_pls_golite062009 |
voltage-gated potassium channel activity | 1.37848954483947 | bayes_pls_golite062009 |
substrate-specific transmembrane transporter activity | 1.36107960937272 | bayes_pls_golite062009 |
metal ion transmembrane transporter activity | 1.34347609298791 | bayes_pls_golite062009 |
ion transmembrane transporter activity | 1.32720756453806 | bayes_pls_golite062009 |
transcription activator activity | 1.3134483946218 | bayes_pls_golite062009 |
cation transmembrane transporter activity | 1.2813343017365 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 0.933012980583336 | bayes_pls_golite062009 |
specific transcriptional repressor activity | 0.69971422997918 | bayes_pls_golite062009 |
transporter activity | 0.14391700968389 | bayes_pls_golite062009 |
catalytic activity | 0.112500532859479 | bayes_pls_golite062009 |
chromatin binding | 0.0908724449159477 | bayes_pls_golite062009 |
transmembrane transporter activity | 0.0733959562343498 | bayes_pls_golite062009 |
Region A: Residues: [197-372] |
1 11 21 31 41 51 | | | | | | 1 SSVLQAAASN QSILQQTGAG LAVSALVTTQ LSSGPAAGTS SQASSTQQQQ PLTSTNVTKK 60 61 TESAKLTSST AAPASGASAS AAVQQAHLHQ QQAQTTSDAI NTENVQAQSQ GGAQGVQGDD 120 121 EDIDEGSAVG GPNSATGPNP ASASASAVHA GVVVKQLASV VDKSSSNHKH KIKDNS |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [373-451] |
1 11 21 31 41 51 | | | | | | 1 VSSVGSEMVI EPKAEYDDDA HDENVEDLTL DEEDMTMEEL DQTAGTSQGG EGSSQTYATW 60 61 QHDRSQDELG LMAQDAQQR |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [452-517] |
1 11 21 31 41 51 | | | | | | 1 DPQDEAGQNE GGESRIRVRN WLMLADKSII GKSSDEPSDK LTQSKKSLIS DAKTTNKTST 60 61 PIRPKV |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [518-629] |
1 11 21 31 41 51 | | | | | | 1 STTTTSTSTA AAAAAAATIA AKQAAAAIAS SNINNNNSSL TQTVTQTVTR IGSIGRTTIA 60 61 CITPANNGNK SSSSNCNVDA ASAAALAAAG VELDSIDDTM TEVIVKIENP ES |
Detection Method: | |
Confidence: | 3.69897 |
Match: | 2dlkA |
Description: | No description for 2dlkA was found. |
Term | Confidence | Notes |
transcription regulator activity | 4.70988788192472 | bayes_pls_golite062009 |
nucleic acid binding | 4.58713908116892 | bayes_pls_golite062009 |
DNA binding | 4.56219307357342 | bayes_pls_golite062009 |
transcription activator activity | 3.52873291636993 | bayes_pls_golite062009 |
transcription factor activity | 3.50954949535763 | bayes_pls_golite062009 |
transcription repressor activity | 3.27542149084008 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 3.22082323675675 | bayes_pls_golite062009 |
binding | 3.10743787485868 | bayes_pls_golite062009 |
sequence-specific DNA binding | 2.53101891154822 | bayes_pls_golite062009 |
chromatin binding | 2.18464662431232 | bayes_pls_golite062009 |
protein binding | 2.05530362750351 | bayes_pls_golite062009 |
specific RNA polymerase II transcription factor activity | 1.63161912031789 | bayes_pls_golite062009 |
transcription factor binding | 1.39608963544799 | bayes_pls_golite062009 |
transcription corepressor activity | 1.34049786451995 | bayes_pls_golite062009 |
transcription cofactor activity | 0.77874411480713 | bayes_pls_golite062009 |
catalytic activity | 0.245893663605433 | bayes_pls_golite062009 |
Region A: Residues: [630-765] |
1 11 21 31 41 51 | | | | | | 1 MPLNDDEDDA VCNEAIEDEN TFDYDLKLGS PLSWTYDAVK IENEEFEDSY LMDNDDDDDD 60 61 LLTTAAATQK HAKQSNEKQM AGSMVAGAGS GGAVKKIVLS AQQQQQLLEQ QQHLQHLQLQ 120 121 PTSQSLQIKL PAIPAT |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [766-963] |
1 11 21 31 41 51 | | | | | | 1 ITTISAPKQM MSGAGTSGSL TPNNNCTLMS NKLGLPVKGQ NLDLHWSHSD DNRYRVLVQN 60 61 KRTRKESLEH SADMIYNADI EKPWVCRNCN RTYKWKNSLK CHLKNECGLP PRYFCSKMCG 120 121 YATNVHSNLK RHLNTKCRDR EKDADDEKKP GSASGNMPVV VGVGNGTAVP VSSSNNNNNG 180 181 GGSSTSSTYT LVFQNDSA |
Detection Method: | |
Confidence: | 52.09691 |
Match: | 2i13A |
Description: | No description for 2i13A was found. |