YRC Public Data Repository - Protein Structure Prediction

Protein:	PA1B2_MOUSE
Organism:	Mus musculus
Length:	229 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PA1B2_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|90083493 - gi\|90083493\|dbj\|BAE90829.1\| unnamed protein product [Macaca fascicularis] PA1B2_PONAB - Platelet-activating factor acetylhydrolase IB subunit beta OS=Pongo abelii GN=PAFAH1B2 PE=2 SV=1 PAFAH1B2 - platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) ENSPTRT00000008026 - null ENSMMUT000000029... - null, null tr\|M3XFC9\|M3XFC9... - Platelet activating factor acetylhydrolase 1b catalytic subunit 2 OS=Felis catus GN=PAFAH1B2 PE=4 SV... ENSOCUP00000010274 - pep:novel chromosome:oryCun2:1:99252374:99273668:-1 gene:ENSOCUG00000011948 transcript:ENSOCUT000000... PA1B2_PONPY - Platelet-activating factor acetylhydrolase IB subunit beta - Pongo pygmaeus (Orangutan) PA1B2_BOVIN - Platelet-activating factor acetylhydrolase IB subunit beta OS=Bos taurus GN=PAFAH1B2 PE=1 SV=1	235.0	[0..1]	[229..1]
gi\|33440467 - gi\|33440467\|gb\|AAH56211.1\| Platelet-activating factor acetylhydrolase, isoform 1b, alpha2 subunit [M...	233.0	[0..1]	[229..1]
gi\|73955102 - gi\|73955102\|ref\|XP_536562.2\| PREDICTED: similar to platelet-activating factor acetylhydrolase, isofo...	232.0	[0..1]	[229..363]
gi\|37590293, gi\|... - gi\|37590293\|gb\|AAH59352.1\| MGC69176 protein [Xenopus laevis], gi\|148230739\|ref\|NP_001080040.1\| hypot...	228.0	[0..1]	[229..1]
PA1B2_CHICK - Platelet-activating factor acetylhydrolase IB subunit beta OS=Gallus gallus GN=PAFAH1B2 PE=2 SV=1	212.0	[0..1]	[224..1]
gi\|30186156, gi\|... - gi\|68382865\|ref\|XP_683731.1\| PREDICTED: similar to Platelet-activating factor acetylhydrolase, isofo...	202.0	[0..3]	[222..2]
PA1B3_BOVIN - Platelet-activating factor acetylhydrolase IB subunit gamma OS=Bos taurus GN=PAFAH1B3 PE=1 SV=1	197.0	[0..3]	[202..2]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQGDSNPAA IPHAAEDIQG DDRWMSQHNR FVLDCKDKEP DVLFVGDSMV QLMQQYEIWR  60
   61 ELFSPLHALN FGIGGDTTRH VLWRLKNGEL ENIKPKVIVV WVGTNNHENT AEEVAGGIEA 120
  121 IVQLINTRQP QAKIIVLGLL PRGEKPNPLR QKNAKVNQLL KVSLPKLANV QLLDIDGGFV 180
  181 HSDGAISCHD MFDFLHLTGG GYAKICKPLH ELIMQLLEET PEEKQTTIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.0
Match:	1fxwF
Description:	Platelet-activating factor acetylhydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.84091517928452	bayes_pls_golite062009
platelet-activating factor acetyltransferase activity	0.732293103277365	bayes_pls_golite062009
protein binding	0.564720396960066	bayes_pls_golite062009
hydrolase activity	0.45071330223777	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: