YRC Public Data Repository - Protein Structure Prediction

Protein:	PROF1_RAT
Organism:	Rattus norvegicus
Length:	140 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PROF1_RAT.

Description	E-value	Query Range	Subject Range
PROF1_BOVIN - Profilin-1 OS=Bos taurus GN=PFN1 PE=1 SV=2	197.0	[0..1]	[140..1]
gi\|1628436 - gi\|1628436\|emb\|CAA65655.1\| profilin [Rattus norvegicus]	196.0	[0..1]	[140..1]
gi\|26389590 - gi\|26389590\|dbj\|BAC25757.1\| unnamed protein product [Mus musculus]	196.0	[0..1]	[140..1]
gi\|61372268, gi\|... - gi\|61372268\|gb\|AAX43813.1\| profilin 1 [synthetic construct], gi\|61372266\|gb\|AAX43812.1\| profilin 1 [...	195.0	[0..1]	[140..1]
gi\|109112914 - gi\|109112914\|ref\|XP_001099416.1\| PREDICTED: profilin 1 [Macaca mulatta] PFN1 - profilin 1 gi\|208967132, gi... - gi\|61355364\|gb\|AAX41132.1\| profilin 1 [synthetic construct], gi\|60814409\|gb\|AAX36300.1\| profilin 1 [...	194.0	[0..1]	[140..1]

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Predicted Domain #1

Region A:
Residues: [1-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGWNAYIDS LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VSITPAEVGV LVGKDRSSFF  60
   61 VNGLTLGGQK CSVIRDSLLQ DGEFTMDLRT KSTGGAPTFN VTVTMTAKTL VLLMGKEGVH 120
  121 GGLINKKCYE MASHLRRSQY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.0
Match:	1hluP
Description:	Profilin (actin-binding protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	7.981958446142	bayes_pls_golite062009
cytoskeletal protein binding	6.51470611165788	bayes_pls_golite062009
actin monomer binding	3.80837480536839	bayes_pls_golite062009
binding	3.26636517628678	bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding	3.08913463974786	bayes_pls_golite062009
protein binding	2.14534188091242	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: