Protein Overview: gi|168776868, gi...

General Information:
Name(s) found:	gi\|187767785 [NCBI NR] gi\|168776868 [NCBI NR]
Description(s) found: Found 2 descriptions. SHOW ALL	gi\|187767785\|gb\|EDU31629.1\| aldehyde-alcohol dehydrogenase [Escherichia coli O157:H7 str. EC4196] [NCBI NR] gi\|168776868\|ref\|ZP_02801875.1\| aldehyde-alcohol dehydrogenase [Escherichia coli O157:H7 str. EC4196] [NCBI NR]
Organism:	Escherichia coli O157:H7 str. EC4196
Length:	891 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVTNVAELN ALVERVKKAQ REYASFTQEQ VDKIFRAAAL AAADARIPLA KMAVAESGMG  60
   61 IVEDKVIKNH FASEYIYNAY KDEKTCGVLS EDDTFGTITI AEPIGIICGI VPTTNPTSTA 120
  121 IFKSLISLKT RNAIIFSPHP RAKDATNKAA DIVLQAAIAA GAPKDLIGWI DQPSVELSNA 180
  181 LMHHPDINLI LATGGPGMVK AAYSSGKPAI GVGAGNTPVV IDETADIKRA VASVLMSKTF 240
  241 DNGVICASEQ SVVVVDSVYD AVRERFATHG GYLLQGKELK AVQDVILKNG ALNAAIVGQP 300
  301 AYKIAELAGF SVPENTKILI GEVTVVDESE PFAHEKLSPT LAMYRAKDFE DAVEKAEKLV 360
  361 AMGGIGHTSC LYTDQDNQPA RVSYFGQKMK TARILINTPA SQGGIGDLYN FKLAPSLTLG 420
  421 CGSWGGNSIS ENVGPKHLIN KKTVAKRAEN MLWHKLPKSI YFRRGSLPIA LDEVITDGHK 480
  481 RALIVTDRFL FNNGYADQIT SVLKAAGVET EVFFEVEADP TLSIVRKGAE LANSFKPDVI 540
  541 IALGGGSPMD AAKIMWVMYE HPETHFEELA LRFMDIRKRI YKFPKMGVKA KMIAVTTTSG 600
  601 TGSEVTPFAV VTDDATGQKY PLADYALTPD MAIVDANLVM DMPKSLCAFG GLDAVTHAME 660
  661 AYVSVLASEF SDGQALQALK LLKEYLPASY HEGSKNPVAR ERVHSAATIA GIAFANAFLG 720
  721 VCHSMAHKLG SQFHIPHGLA NALLICNVIR YNANDNPTKQ TAFSQYDRPQ ARRRYAEIAD 780
  781 HLGLSAPGDR TAAKIEKLLA WLETLKAELG IPKSIREAGV QEADFLANVD KLSEDAFDDQ 840
  841 CTGANPRYPL ISELKQILLD TYYGRDYVEG ETAAKKEAAP AKAEKKAKKS A

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..447]	PSI-BLAST	134.0	Aldehyde reductase (dehydrogenase), ALDH
2	View Details	[448..891]	PSI-BLAST	96.69897	Crystal Structure of Lactaldehyde reductase

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
oxidoreductase activity	4.47226217021998	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	4.34495776828926	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	3.37049090049734	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3.2867555127991	bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity	2.81851373615334	bayes_pls_golite062009
catalytic activity	2.80804701752928	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	1.80313175632526	bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity	1.59279206536309	bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity	1.15620590715864	bayes_pls_golite062009
binding	0.637403449596354	bayes_pls_golite062009
NAD or NADH binding	0.00649065522387682	bayes_pls_golite062009

2

Term	Confidence	Notes
alcohol dehydrogenase (NAD) activity	5.26400058766942	bayes_pls_golite062009
oxidoreductase activity	3.07409531087588	bayes_pls_golite062009
alcohol dehydrogenase activity, metal ion-independent	3.05722501802075	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.83823088483915	bayes_pls_golite062009
catalytic activity	2.37357608468991	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2.10085302216488	bayes_pls_golite062009
binding	1.15096180564234	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	0.831155115586418	bayes_pls_golite062009
cation binding	0.319000821544479	bayes_pls_golite062009
metal ion binding	0.319000821544479	bayes_pls_golite062009
ion binding	0.313606245452103	bayes_pls_golite062009
protein binding	0.295023706645045	bayes_pls_golite062009
transition metal ion binding	0.259889634539407	bayes_pls_golite062009
hydroxyacid-oxoacid transhydrogenase activity	0.146499147589879	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0904828025133766	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.70

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle