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Protein Overview: SYH_YERPY

General Information:
Name(s) found: SYH_YERPY [Swiss-Prot]
Description(s) found:
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  • gi|229470708|sp|B1JS06.1|SYH_YERPY RecName: Full=Histidyl-tRNA synthetase; AltName: Full=Histidine--tRNA ligase; Short=HisRS [NCBI NR]
  • gi|170023540|ref|YP_001720045.1| histidyl-tRNA synthetase [Yersinia pseudotuberculosis YPIII] [NCBI NR]
  • gi|169750074|gb|ACA67592.1| histidyl-tRNA synthetase [Yersinia pseudotuberculosis YPIII] [NCBI NR]
  • Histidine--tRNA ligase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=hisS PE=3 SV=1 [Swiss-Prot]
    • Organism: Yersinia pseudotuberculosis YPIII
    Length: 424 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKNIQAIRG MNDYLPADTA IWQRIESILK QVLSGYGYSE IRMPIVEQTP LFKRAIGEVT  60
   61 DVVEKEMYTF DDRNGESLTL RPEGTAGCVR AGIEHGLLYN QEQRLWYIGP MFRYERPQKG 120
  121 RYRQFHQLGA EVFGLPGPDI DAELILLTAR WWRALGIFEH VKLELNSIGS LAARADYREA 180
  181 LVAFLEQHVE VLDEDCKRRM YSNPLRVLDS KNPDVQQLLD DAPKLSDYLD EESKQHFAGL 240
  241 CELLDKASIP YTVNERLVRG LDYYNRTVFE WVTHSLGAQG TVCAGGRYDG LVEQLGGRAT 300
  301 PAVGFAMGLE RLVLLVQAVN ADFQVPATVD AYVISSGEGA QSAAMLLAES LRDALPTLKI 360
  361 MTNYGGGNVK KQFTRADKWG ARVALMLGES EVAAQQVVVK DLRNGEQETL AQADVAARLA 420
  421 LMLG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..424] PSI-BLAST 79.39794 Histidyl-tRNA synthetase (HisRS), C-terminal domain; Histidyl-tRNA synthetase (HisRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  5.91343220471745 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  2.99105702052936 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.46505535069103 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.29229136935761 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  1.82594054955281 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  1.72324031407565 bayes_pls_golite062009
  • binding
    		•  0.966824335333342 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.375542987753806 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.281662799812287 bayes_pls_golite062009
  • protein binding
    		•  0.0804954454681041 bayes_pls_golite062009
  • DNA binding
    		•  0.0309732052586011 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.00572514744734753 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle