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Protein Overview: lig-1

General Information:
Name(s) found: lig-1 / CE37481 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00002985 locus:lig-1 DNA ligase 1 status:Confirmed UniProt:Q27474 protein_id:CAD44112.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 210 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    DNA repair [IEALink to PubMed article]
    DNA replication [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    DNA recombination [IEALink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    DNA binding [IEALink to PubMed article]
    DNA ligase (ATP) activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFFSKAGKAA VEWAKGSKVP YKEFALTLEK IEELSGKKKV DELAQFFTKV LDFSPDDLTA  60
   61 CVYMSVNQLG PSYEGLELGV AENSLIKAVA KATGRTEGKI KEDLRAKGDL GTVAQQSRSN 120
  121 QKMLAVPKAL TVPTVFNKLT EIAKLSGTSA MNKKVDAISA LLIACQGIEA RFLVRMLAGK 180
  181 MRIGLGEQSV LSALGHAFTL SKITDQKRMP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..210] PSI-BLAST 52.0 Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle