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Protein Overview: GBPC_DICDI

General Information:
Name(s) found: GBPC_DICDI [Swiss-Prot]
Description(s) found:
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  • gi|74843506|sp|Q8MVR1.1|GBPC_DICDI RecName: Full=Cyclic GMP-binding protein C; AltName: Full=RasGEF domain-containing protein T [NCBI NR]
  • gi|60463707|gb|EAL61887.1| putative protein serine/threonine kinase [Dictyostelium discoideum] [NCBI NR]
  • gi|21069539|gb|AAM34041.1|AF481923_1 cyclic GMP-binding protein C [Dictyostelium discoideum] [NCBI NR]
  • Cyclic GMP-binding protein C OS=Dictyostelium discoideum GN=gbpC PE=1 SV=1 [Swiss-Prot]
  • cyclic GMP-binding protein C [Dictyostelium discoideum] [nrdb_11152004_Chlamydomonas]
  • |Protein| gene: gbpC on chromosome: 5 position 4897869 to 4905932 [dicty_predictions_protein.fasta]
    • Organism: Dictyostelium discoideum
    Length: 2631 amino acids

    Gene Ontology:
    Cellular Component: intracellular [ISS]
    Biological Process: small GTPase mediated signal transduction [ISS]
    regulation of small GTPase mediated signal transduction [IEA]
    positive regulation of protein kinase activity [IMP]
    establishment or maintenance of cell polarity [IMP]
    positive regulation of cellular component movement [TAS]
    positive regulation of Ras protein signal transduction [IDA]
    protein amino acid phosphorylation [ISS]
    cell-substrate adhesion [IMP]
    regulation of chemotaxis [IMP]
    Molecular Function: GTP binding [ISS]
    ATP binding [ISS]
    protein binding [IEA]
    guanyl-nucleotide exchange factor activity [ISS]
    Ras guanyl-nucleotide exchange factor activity [IDA]
    protein kinase activity [ISS]
    cGMP binding [IDA][IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQKQKPIRF QDYQFTATKD EAYGRSDRYV KQFLNKNLLK KKDGTLGTAE ELLTLIQQSN  60
   61 INVVTASTGG AAMGAMLNHT VSTINLTGSG SVPTYNPSDN RNSGSHVITS TNSVISNSSI 120
  121 SSTGVINNNI NNNSNINSNT GTTTTTISLP NNTEIKTALV STGSQNASDT AQIDIEFHLS 180
  181 YTQLVTLPPS IFSLIWIQKL VLTHHNIKTL SEDIGKLQQL QVLVLENNRL INLPQSIGDL 240
  241 VNLKRLEVDN NHLVSLCSLE RLSKLEVLSV NNNKLTLLPT SIASLSSLKT LNIKSNPIIT 300
  301 PPSTVVSKGL KDIVSFLREL ETGARPCLRS KLVVLGDPGV GKTSVVQCMK GKKKKTNVTS 360
  361 SSINIGGSSG SEVGIEIDQY DFDVVFDEDD KKRRVITLST WDIANQDVYF ASSQLFDSER 420
  421 SVYIVVFNLN NDDFSAIEYW LHCIMSTSPN SPIVLVGTHI DAFENLNVVN AVLESVASRF 480
  481 QKRFTNIQAI ISVSCTTGYD VDKLRQLIED IIKTQPYLKE KVPSSFFTLE EALIEVKKKR 540
  541 IPPVMMWQEY INLANICNLK DSVQIQRATE FLHNIGSIVY FNDLNSSTVG KMVILDQQWI 600
  601 INCMSSLITS KLLINNCNGI VRQSDLELVW KAPTYPEHLH PALLSIMQAF EICRSLSPSD 660
  661 LVRPEEVNEK EVMGDRNLVP NLLSDNTNIV AQWDDFIDPD TILLNRQYHL PFLPEKFFGK 720
  721 LIIHLMNFTK VESCQKRAVI LRNQDNHEAL IELKTIKDNK DGTFKKILTV DVRGLVSPVS 780
  781 LLRIVTDTIE SLFSQWYKLD IKRYISCYEC AILYDRNPTL FTIEECELAV IDGKTVLTCN 840
  841 QKSDSDRVST SHRLKLDILA PDISMVDIPI PRFNLSEVKI NKEVGRGAFG IVYEAEWMSE 900
  901 WIALKKLLLP SSTDTTNLNG NGEVMVYDDP DQLIEDRLRV FREFRHEVYY MSGLNHPNVM 960
  961 KISGFCIQPL CMALEYVRYG SLYSLLSNSS IEISWGLRLQ IASEIAKGMQ HLHSHNPPVI1020
 1021 HRDLKSPNIL LNGITEGQNS VATIIDFGTS TALYGGAALI RCVDQPLWLG PEVLAGTAYS1080
 1081 EPSDVYSFGI ILWELYTRAH PFDEFQFGQW MSKLEDEIIR GLRPTIPPTC PPEYVELIQS1140
 1141 CWTHEPNSRP TFTSIVEILG QIKKKFAPLP FTHPPHIRNM MRKSRSSSIS EAMLPSNLLH1200
 1201 LNLNGINNNN NNSNNNNNSI PVTTISLTSS GTSPTNSPVG GLLSQSLTQP ITSGGSTSGI1260
 1261 LSTSVNRDNS SLVSASSLGN NTSTSSLASL VSNNSGLHHS PSASDGLNDY YGADNNNNNN1320
 1321 DSTMDFFQDI FTEEENEQPY PFADDDQQKG ILFGFDEEQT NPSASSVSII IAATMAKMIE1380
 1381 MMTKGESSAT LKSEHISTRR RSDTAGKNGV PPHWRNSVPL STNSSTTLDE TFIDDFIYVY1440
 1441 RSFTTPRNIF KLLVRRFFGP RHTDKVDTFT IKKFEQKKAA IRQGIAVFLR KWVADITELE1500
 1501 FRQEEFWLYH NTVAFTKQFI ASEFPTIATQ IYGTLTTHED EVNLTNQRFL QIAFSESEIQ1560
 1561 IDRAMSSMQL TTPKPFRSQK NLANSYNSQS GGGDSSFYYQ PSSNDVSRVF LNLATGMRDP1620
 1621 LLGITVKEKK FKKDKVSTLC CSGSEIIDWI TKCMPIKREE ASILVLDMLM KQFFIQISDD1680
 1681 GIPISNQKGT NPTFSDSPTS FYMFLEDDPE LIARQYTFLE LKYLQNIHPR ELLGFSVGLV1740
 1741 MPNENEKDPE KWRQSNFPHI YDYFRWFNKM TMLVSTEILR QRDIKQRASI IEKYISIALE1800
 1801 YLSLWNFNGI MQVLSSLHSE PISRLSATWA KVSQRSMDCF YELSRLMLPE SNYLPLRTAL1860
 1861 ASQKPNTIIQ ASPLYPNISA YMVHTVCPTI PFLGALIADL SQTCTENPTF ISSGGEKMIN1920
 1921 ILRVKRLSKK MKMFKEYKEM PTQYLPALTT IPLQYYEHYV NDLKALDSLQ IDRLSDIERK1980
 1981 LEIICEKNGT TNDDKEKGDE NGGGLTSSNF FGNGSDELTE RDWTILLTNA SVIAYNRGDV2040
 2041 VMEENAINTH LYRIKSGAIS VEKKDKEGIN CKVATMFAPK MFGEMSFLGN KTTARLTVDE2100
 2101 ESDLYVMDIP FLNNLFNGHP RLGAKFYKIM ANQLAIRLKN LPWSKPKNTT GGSSSSNQSA2160
 2161 GPDNILGTTP TGISSSGGGL TSLLNQNLSS IMSLSNSNTP PASPRVMTTP TLPSPPAPLQ2220
 2221 SPPTSGISSP TTTTSTTTDQ QKINNTIFQN VHPTINVHRT SSSANLVSPH GRPSNSGFGH2280
 2281 SSGGERTINK DPHQRDSGSM DKPILSLGSG GTPRGDGARS GSISYLGRTQ TSTSPLNEGL2340
 2341 SGGQQPVMKK NDQEFCQRFA LVDEIVIKDY PCSLNRSGRL YISQQHVCFY SKFFGYKTKK2400
 2401 VIPFKNIDKL ICINVNQIEL TRLKNTVPSN YRLTFQTGKD REDAFSMIHI LWDSSKVSNS2460
 2461 SSDEIKNKLA AERKKVNNLT LKTRSNKNKG DELTKEDWEL IGCEGSRSST FKKDEVIIRE2520
 2521 GERMQKIFQI GKGVCRIEKS VPVAPGSSEM KKVVLGTMKQ DDTFGEITYL LNGETTADVI2580
 2581 ADTDQTEVYT IEGQFVNILF DLNPALASKW FKYLATALNK TLIERESQLY A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle