Protein Overview: TPA_MOUSE

General Information:
Name(s) found:	TPA_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74189491\|dbj\|BAE22749.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|74189332\|dbj\|BAE22698.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|38181793\|gb\|AAH61508.1\| Plasminogen activator, tissue [Mus musculus] [NCBI NR] gi\|34786061\|gb\|AAH57967.1\| Plasminogen activator, tissue [Mus musculus] [NCBI NR] gi\|170763477\|ref\|NP_032898.2\| plasminogen activator, tissue preproprotein [Mus musculus] [NCBI NR] gi\|158931157\|sp\|P11214.3\|TPA_MOUSE RecName: Full=Tissue-type plasminogen activator; Short=t-plasminogen activator; Short=t-PA; Short=tPA; Contains: RecName: Full=Tissue-type plasminogen activator chain A; Contains: RecName: Full=Tissue-type plasminogen ac [NCBI NR] gi\|148700932\|gb\|EDL32879.1\| plasminogen activator, tissue [Mus musculus] [NCBI NR] Tissue-type plasminogen activator OS=Mus musculus GN=Plat PE=1 SV=3 [Swiss-Prot] Plasminogen activator, tissue [Mus musculus]gi\|34786061\|gb\|AAH57967.1\| Plasminogen activator, tissue [Mus musculus] [nrdb_11152004_Chlamydomonas] Plasminogen activator, tissue [ipi.MOUSE.v3.06.fasta] Tax_Id=10090 Plasminogen activator, tissue [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] Tissue-type plasminogen activator precursor (t-plasminogen activator) (t-PA) (tPA) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] plasminogen activator, tissue preproprotein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] plasminogen activator, tissue [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Plasminogen activator, tissue [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 PLASMINOGEN ACTIVATOR, TISSUE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Plat Tissue-type plasminogen activator [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Plat Tissue-type plasminogen activator precursor [ipi.MOUSE_jw_12may08.contam.fasta] Tax_Id=10090 Gene_Symbol=Plat Plasminogen activator, tissue [zeeyong.fasta] Tax_Id=10090 Gene_Symbol=Plat Tissue-type plasminogen activator precursor ENSMUSG00000031538 IPI00319513 [IPIxENS.MOUSE_plus_REVERSE.fasta] tissue-type plasminogen activator preproprotein [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00319513.4\|SWISS-PROT:P11214\|ENSEMBL:ENSMUSP00000033941\|REFSEQ:NP_032898 Tax_Id=10090 Gene_Symbol=Plat Tissue-type plasminogen activator [ipi.MOUSE.fasta.20090209] Tissue-type plasminogen activator OS=Mus musculus GN=Plat [011711_HMR.fasta] sp\|P11214\|TPA_MOUSE Tissue-type plasminogen activator OS=Mus musculus GN=Plat PE=1 SV=3 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	559 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN][IDA] apical part of cell [IDA] cytoplasm [UNKNOWN][IDA] secretory granule [IDA] synapse [UNKNOWN] extracellular region [IEA]
Biological Process:	smooth muscle cell migration [IMP] response to hypoxia [IMP] proteolysis [IDA] platelet-derived growth factor receptor signaling pathway [IDA][IMP] synaptic transmission, glutamatergic [UNKNOWN]
Molecular Function:	catalytic activity [IEA] serine-type peptidase activity [IEA] serine-type endopeptidase activity [IDA] peptidase activity [IEA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRELLCVLL LCGLAFPLPD QGIHGRFRRG ARSYRATCRD EPTQTTYQQH QSWLRPMLRS  60
   61 SRVEYCRCNS GLVQCHSVPV RSCSEPRCFN GGTCQQALYF SDFVCQCPDG FVGKRCDIDT 120
  121 RATCFEEQGI TYRGTWSTAE SGAECINWNS SVLSLKPYNA RRPNAIKLGL GNHNYCRNPD 180
  181 RDLKPWCYVF KAGKYTTEFC STPACPKGKS EDCYVGKGVT YRGTHSLTTS QASCLPWNSI 240
  241 VLMGKSYTAW RTNSQALGLG RHNYCRNPDG DARPWCHVMK DRKLTWEYCD MSPCSTCGLR 300
  301 QYKRPQFRIK GGLYTDITSH PWQAAIFVKN KRSPGERFLC GGVLISSCWV LSAAHCFLER 360
  361 FPPNHLKVVL GRTYRVVPGE EEQTFEIEKY IVHEEFDDDT YDNDIALLQL RSQSKQCAQE 420
  421 SSSVGTACLP DPNLQLPDWT ECELSGYGKH EASSPFFSDR LKEAHVRLYP SSRCTSQHLF 480
  481 NKTVTNNMLC AGDTRSGGNQ DLHDACQGDS GGPLVCMINK QMTLTGIISW GLGCGQKDVP 540
  541 GVYTKVTNYL DWIHDNMKQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TPA_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: