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Protein Overview: EG10192

General Information:
Name(s) found: cysK / EG10192 [EcoGene]
Description(s) found:
Found 4 descriptions.
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  • cysteine synthase A, O-acetylserine sulfhydrolase A subunit / Cysteine synthase A, O-acetylserine sulfhydrylase A; homodimeric; selenate, azaserine, chromate resistance; alkali-inducible, sulfate starvation-inducible protein SSI5; cysteine desulfhydrase [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    cysteine synthase complex [IDALink to PubMed article]
    Biological Process: cellular amino acid biosynthetic process [IDALink to PubMed article]
    cysteine biosynthetic process from serine [IDALink to PubMed article][IEA][IMPLink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEA]
    transferase activity [IDALink to PubMed article][IEA]
    cysteine synthase activity [IDALink to PubMed articleLink to PubMed article][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKIFEDNSL TIGHTPLVRL NRIGNGRILA KVESRNPSFS VKCRIGANMI WDAEKRGVLK  60
   61 PGVELVEPTS GNTGIALAYV AAARGYKLTL TMPETMSIER RKLLKALGAN LVLTEGAKGM 120
  121 KGAIQKAEEI VASNPEKYLL LQQFSNPANP EIHEKTTGPE IWEDTDGQVD VFIAGVGTGG 180
  181 TLTGVSRYIK GTKGKTDLIS VAVEPTDSPV IAQALAGEEI KPGPHKIQGI GAGFIPANLD 240
  241 LKLVDKVIGI TNEEAISTAR RLMEEEGILA GISSGAAVAA ALKLQEDESF TNKNIVVILP 300
  301 SSGERYLSTA LFADLFTEKE LQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..323] PSI-BLAST 97.522879 O-acetylserine sulfhydrylase (Cysteine synthase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cysteine synthase activity
    		•  5.18562032111987 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • cystathionine beta-synthase activity
    		•  1.4517088142802 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.04832999357666 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • threonine synthase activity
    		•  0.727838845253199 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  0.37325071016009 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle