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Protein Overview: EG10077

General Information:
Name(s) found: aroE / EG10077 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • dehydroshikimate reductase, NAD(P)-binding / Shikimate 5-dehydrogenase [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 272 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: aromatic amino acid family biosynthetic process [IEA]
    metabolic process [IEA]
    oxidation reduction [IEA]
    cellular amino acid biosynthetic process [IEA]
    Molecular Function: NADP or NADPH binding [IEA]
    protein binding [IPILink to PubMed article]
    catalytic activity [IEA]
    oxidoreductase activity [IEA]
    shikimate 5-dehydrogenase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METYAVFGNP IAHSKSPFIH QQFAQQLNIE HPYGRVLAPI NDFINTLNAF FSAGGKGANV  60
   61 TVPFKEEAFA RADELTERAA LAGAVNTLMR LEDGRLLGDN TDGVGLLSDL ERLSFIRPGL 120
  121 RILLIGAGGA SRGVLLPLLS LDCAVTITNR TVSRAEELAK LFAHTGSIQA LSMDELEGHE 180
  181 FDLIINATSS GISGDIPAIP SSLIHPGIYC YDMFYQKGKT PFLAWCEQRG SKRNADGLGM 240
  241 LVAQAAHAFL LWHGVLPDVE PVIKQLQEEL SA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..272] PSI-BLAST 83.045757 Shikimate 5-dehydrogenase AroE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.69771604880532 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.714637370305282 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.418775403210681 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.32207755075663 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] reductase activity
    		•  0.192594057004213 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle