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Protein Overview: EG10359

General Information:
Name(s) found: fur / EG10359 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • ferric iron uptake regulon transcriptional repressor; autorepressor / Ferric iron uptake global transcriptional repressor; Fe(2)-responsive; zinc metalloprotein [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 148 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article][IEA]
    Biological Process: transcription [IEA]
    regulation of transcription, DNA-dependent [IEA]
    Molecular Function: DNA binding [IEA]
    zinc ion binding [IDALink to PubMed article][IEA]
    transcription factor activity [IEA]
    protein binding [IPILink to PubMed article]
    iron ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDNNTALKK AGLKVTLPRL KILEVLQEPD NHHVSAEDLY KRLIDMGEEI GLATVYRVLN  60
   61 QFDDAGIVTR HNFEGGKSVF ELTQQHHHDH LICLDCGKVI EFSDDSIEAR QREIAAKHGI 120
  121 RLTNHSLYLY GHCAEGDCRE DEHAHEGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] PSI-BLAST 35.69897 Ferric uptake regulator

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.51306541310201 bayes_pls_golite062009
  • DNA binding
    		•  4.12876602944304 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.12610640813616 bayes_pls_golite062009
  • transcription factor activity
    		•  3.36245551077648 bayes_pls_golite062009
  • binding
    		•  2.88885372623841 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.57171040630767 bayes_pls_golite062009
  • transcription activator activity
    		•  1.46816740214642 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.35320462873179 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.77269240913386 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle