Protein Overview: EG10462

General Information:
Name(s) found:	htpX / EG10462 [EcoGene]
Description(s) found: SHOW ONLY BEST	putative endopeptidase / Zinc metalloprotease HtpX, membrane-bound; cleaves SecY in vivo and in vitro; self-cleaves; M48 family [EcoGene] predicted endopeptidase [Escherichia coli K12] [nr-271106-contam.fasta] heat shock protein HtpX [Escherichia coli K12] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] predicted endopeptidase [Escherichia coli str. K-12 substr. MG1655] [Ecoli-contam-Dam1-Mind-COMA-MBP-110.fasta] putative endopeptidase [Escherichia coli str. K-12 substr. MG1655] [c_elegans-WS236-ecoli-05Mar2013-contam.fasta]
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	293 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] plasma membrane [IEA]
Biological Process:	proteolysis [IEA] response to stress [IEA]
Molecular Function:	zinc ion binding [IEA] metal ion binding [IEA] metalloendopeptidase activity [IDA][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRIALFLLT NLAVMVVFGL VLSLTGIQSS SVQGLMIMAL LFGFGGSFVS LLMSKWMALR  60
   61 SVGGEVIEQP RNERERWLVN TVATQARQAG IAMPQVAIYH APDINAFATG ARRDASLVAV 120
  121 STGLLQNMSP DEAEAVIAHE ISHIANGDMV TMTLIQGVVN TFVIFISRIL AQLAAGFMGG 180
  181 NRDEGEESNG NPLIYFAVAT VLELVFGILA SIITMWFSRH REFHADAGSA KLVGREKMIA 240
  241 ALQRLKTSYE PQEATSMMAL CINGKSKSLS ELFMTHPPLD KRIEALRTGE YLK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
peptidase activity	3.52170890235712	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	3.20265930105587	bayes_pls_golite062009
metallopeptidase activity	2.46762211541241	bayes_pls_golite062009
hydrolase activity	2.3590043825345	bayes_pls_golite062009
endopeptidase activity	2.3107572739426	bayes_pls_golite062009
metalloendopeptidase activity	1.69802747425985	bayes_pls_golite062009
catalytic activity	0.843772148375291	bayes_pls_golite062009
binding	0.655247478888488	bayes_pls_golite062009
protein binding	0.273409914175328	bayes_pls_golite062009
exopeptidase activity	0.160545038651425	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..69]	Pfam	19.744727	No description for PF06509.2 was found. No confident structure predictions are available.
2	View Details	[70..152]	FFAS03	1.04	Zinc protease
3	View Details	[153..293]	Pfam	3.508638	No description for PF01435.9 was found. No confident structure predictions are available.

Protein Overview: EG10462

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: