Protein Overview: PFKA2_YEAST

General Information:
Name(s) found:	PFKA2_YEAST [Swiss-Prot]
Description(s) found: Found 2 descriptions. SHOW ALL	ATP-dependent 6-phosphofructokinase subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PFK2 PE=1 SV=4 [Swiss-Prot]
Organism:	Saccharomyces cerevisiae S288c
Length:	959 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTTPFVNG TSYCTVTAYS VQSYKAAIDF YTKFLSLENR SSPDENSTLL SNDSISLKIL  60
   61 LRPDEKINKN VEAHLKELNS ITKTQDWRSH ATQSLVFNTS DILAVKDTLN AMNAPLQGYP 120
  121 TELFPMQLYT LDPLGNVVGV TSTKNAVSTK PTPPPAPEAS AESGLSSKVH SYTDLAYRMK 180
  181 TTDTYPSLPK PLNRPQKAIA VMTSGGDAPG MNSNVRAIVR SAIFKGCRAF VVMEGYEGLV 240
  241 RGGPEYIKEF HWEDVRGWSA EGGTNIGTAR CMEFKKREGR LLGAQHLIEA GVDALIVCGG 300
  301 DGSLTGADLF RSEWPSLIEE LLKTNRISNE QYERMKHLNI CGTVGSIDND MSTTDATIGA 360
  361 YSALDRICKA IDYVEATANS HSRAFVVEVM GRNCGWLALL AGIATSADYI FIPEKPATSS 420
  421 EWQDQMCDIV SKHRSRGKRT TIVVVAEGAI AADLTPISPS DVHKVLVDRL GLDTRITTLG 480
  481 HVQRGGTAVA YDRILATLQG LEAVNAVLES TPDTPSPLIA VNENKIVRKP LMESVKLTKA 540
  541 VAEAIQAKDF KRAMSLRDTE FIEHLNNFMA INSADHNEPK LPKDKRLKIA IVNVGAPAGG 600
  601 INSAVYSMAT YCMSQGHRPY AIYNGWSGLA RHESVRSLNW KDMLGWQSRG GSEIGTNRVT 660
  661 PEEADLGMIA YYFQKYEFDG LIIVGGFEAF ESLHQLERAR ESYPAFRIPM VLIPATLSNN 720
  721 VPGTEYSLGS DTALNALMEY CDVVKQSASS TRGRAFVVDC QGGNSGYLAT YASLAVGAQV 780
  781 SYVPEEGISL EQLSEDIEYL AQSFEKAEGR GRFGKLILKS TNASKALSAT KLAEVITAEA 840
  841 DGRFDAKPAY PGHVQQGGLP SPIDRTRATR MAIKAVGFIK DNQAAIAEAR AAEENFNADD 900
  901 KTISDTAAVV GVKGSHVVYN SIRQLYDYET EVSMRMPKVI HWQATRLIAD HLVGRKRVD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..185]	deduced	N/A	No confident structure predictions are available.
2	View Details	[186..363] [483..539]	PSI-BLAST	635.9897	ATP-dependent phosphofructokinase
3	View Details	[364..482] [540..548]	PSI-BLAST	635.9897	ATP-dependent phosphofructokinase
4	View Details	[549..827]	PSI-BLAST	112.08661	Pyrophosphate-dependent phosphofructokinase
5	View Details	[828..959]	ORFEUS	12.5	ATP-dependent phosphofructokinase

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
6-phosphofructokinase activity	12.7403693686468	bayes_pls_golite062009
phosphofructokinase activity	11.7059647240147	bayes_pls_golite062009
fructose-6-phosphate binding	9.55959144901554	bayes_pls_golite062009
fructose binding	9.55841643584799	bayes_pls_golite062009
carbohydrate kinase activity	9.54757838113048	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	3.19280659830412	bayes_pls_golite062009
kinase activity	2.85624705588769	bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity	2.7198911999025	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.67472251964197	bayes_pls_golite062009
sugar binding	2.21212411210899	bayes_pls_golite062009
monosaccharide binding	2.05358532613083	bayes_pls_golite062009
transferase activity	1.97789134877808	bayes_pls_golite062009
catalytic activity	1.89212073381079	bayes_pls_golite062009
protein binding	1.76136621968843	bayes_pls_golite062009
binding	1.57437723650762	bayes_pls_golite062009
carbohydrate binding	0.97067862054315	bayes_pls_golite062009
hydrolase activity	0.276140444059183	bayes_pls_golite062009

3

Term	Confidence	Notes
6-phosphofructokinase activity	12.7403693686468	bayes_pls_golite062009
phosphofructokinase activity	11.7059647240147	bayes_pls_golite062009
fructose-6-phosphate binding	9.55959144901554	bayes_pls_golite062009
fructose binding	9.55841643584799	bayes_pls_golite062009
carbohydrate kinase activity	9.54757838113048	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	3.19280659830412	bayes_pls_golite062009
kinase activity	2.85624705588769	bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity	2.7198911999025	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.67472251964197	bayes_pls_golite062009
sugar binding	2.21212411210899	bayes_pls_golite062009
monosaccharide binding	2.05358532613083	bayes_pls_golite062009
transferase activity	1.97789134877808	bayes_pls_golite062009
catalytic activity	1.89212073381079	bayes_pls_golite062009
protein binding	1.76136621968843	bayes_pls_golite062009
binding	1.57437723650762	bayes_pls_golite062009
carbohydrate binding	0.97067862054315	bayes_pls_golite062009
hydrolase activity	0.276140444059183	bayes_pls_golite062009

4

No functions predicted.

5

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.91

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle