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Protein Overview: ISPE_GEOSL

General Information:
Name(s) found: ISPE_GEOSL [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=ispE PE=3 SV=1 [Swiss-Prot]
    • Organism: Geobacter sulfurreducens PCA
    Length: 279 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: isoprenoid biosynthetic process [ISSLink to PubMed article]
    Molecular Function: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKLTLKAPA KVNYRLDVLR RRPDGYHDLR MIMQRIDLCD EIEICLTDGP GIRVVCGREG  60
   61 VPDGPGNIAW RAADALLALS ADKPGIDISI TKKIPVAAGL GGGSSDAATV LMGVNELLGL 120
  121 DLPEKRLREI GVTLGADVPF FIFGRTALAE GIGEELTAID RVPAAWIVVV NPNVPVSTAW 180
  181 VYQNLQLTGE AARVKIPRFF ESVAEVCAIL SNDLESVTIP RYPVIGEIKR ELLAAGALGS 240
  241 LMSGSGPTVF ALFEEEDAAV RAAEMMRARS WFAAAVRTI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..279] PSI-BLAST 51.0 Ternary complex of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
    		•  1.9881460462076 bayes_pls_golite062009
  • catalytic activity
    		•  1.20658247466773 bayes_pls_golite062009
  • diphosphomevalonate decarboxylase activity
    		•  1.0502744466494 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle