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Protein Overview: TYSY_PSEAE

General Information:
Name(s) found: TYSY_PSEAE [Swiss-Prot]
Description(s) found:
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  • gi|9946191|gb|AAG03731.1|AE004472_3 thymidylate synthase [Pseudomonas aeruginosa PAO1] [NCBI NR]
  • gi|15595539|ref|NP_249033.1| thymidylate synthase [Pseudomonas aeruginosa PAO1] [NCBI NR]
  • Thymidylate synthase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=thyA PE=3 SV=1 [Swiss-Prot]
  • thymidylate synthase [Pseudomonas aeruginosa PAO1]gi|9946191|gb|AAG03731.1| thymidylate synthase [Pseudomonas aeruginosa PAO1]gi|22096233|sp|Q9I6F1|TYSY_PSEAE Thymidylate synthase (TS) (TSase)gi|32043513|ref|ZP_00140775.1| COG0207: Thymidylate synthase [nrdb_11152004_Chlamydomonas]
  • thymidylate synthase [Pseudomonas aeruginosa PAO1] [nr-271106-contam.fasta]
  • synthase[Pseudomonas aeruginosa PAO1 PAO1-UW] [P_aeruginosa_PAO1_PGD-contam.fasta]
    • Organism: Pseudomonas aeruginosa PAO1
    Length: 264 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQYLDLMRH VREHGTFKSD RTGTGTYSVF GHQMRFDLAA GFPLVTTKKC HLKSIVHELL  60
   61 WFLKGSTNIA YLKEHGVSIW DEWADENGDL GPVYGYQWRS WPAPDGRHID QIANLMAMLK 120
  121 KNPDSRRLIV SAWNPALIDE MALPPCHALF QFYVADGKLS CQLYQRSADI FLGVPFNIAS 180
  181 YALLTLMVAQ VAGLQPGEFI WTGGDCHLYA NHLEQADLQL TREPLPLPSM KLNPEVKDLF 240
  241 DFRFEDFELV GYEAHPHIKA PVAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264] PSI-BLAST 129.0 Thymidylate synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • thymidylate synthase activity
    		•  6.6988475347328 bayes_pls_golite062009
  • 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
    		•  6.29181090719132 bayes_pls_golite062009
  • binding
    		•  1.89072001556053 bayes_pls_golite062009
  • catalytic activity
    		•  1.73427871128495 bayes_pls_golite062009
  • transferase activity
    		•  1.72626940963556 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.927096828883487 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.91282507161672 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.61

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle