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Protein Overview: RSMA_MANSM

General Information:
Name(s) found: RSMA_MANSM [Swiss-Prot]
Description(s) found:
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  • gi|62900507|sp|Q65UX3.1|KSGA_MANSM RecName: Full=Dimethyladenosine transferase; AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase; AltName: Full=16S rRNA dimethylase; AltName: Full=High level kasugamycin resistance protein ksg [NCBI NR]
  • gi|52424685|ref|YP_087822.1| dimethyladenosine transferase [Mannheimia succiniciproducens MBEL55E] [NCBI NR]
  • gi|52306737|gb|AAU37237.1| KsgA protein [Mannheimia succiniciproducens MBEL55E] [NCBI NR]
  • Ribosomal RNA small subunit methyltransferase A OS=Mannheimia succiniciproducens (strain MBEL55E) GN=rsmA PE=3 SV=1 [Swiss-Prot]
  • Dimethyladenosine transferase OS=Mannheimia succiniciproducens (strain MBEL55E) GN=ksgA PE=3 SV=1 [Swiss-Prot]
  • KsgA protein [Mannheimia succiniciproducens MBEL55E]gi|52306737|gb|AAU37237.1| KsgA protein [Mannheimia succiniciproducens MBEL55E] [nrdb_11152004_Chlamydomonas]
  • KsgA protein [Mannheimia succiniciproducens MBEL55E] [nr-271106-contam.fasta]
  • dimethyladenosine transferase [Mannheimia succiniciproducens MBEL55E] [nr-271106-contam.fasta]
  • Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (16S rRNA dimethylase) (High level kasugamycin resistance protein ksgA) (Kasugamycin dimethyltransferase) [nr-271106-contam.fasta]
    • Organism: Mannheimia succiniciproducens MBEL55E
    Length: 288 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSKRHLGHT ARKRFGQNFL HDDNVIQGIV AAIYPQKGQF LVEIGPGLGA LTEPVADQTD  60
   61 RLTVVELDRD LAQRLRHHPF LHQKLNVIET DAMQFDFGKL YEDEHLAEQG QKLRVFGNLP 120
  121 YNISTPLIFH LLKFYDKIQD MHFMLQKEVV KRLCAAPNSK AYGRLTIMTQ YFCQVMPVLE 180
  181 VPPTAFKPAP KVDSAVVRLI PHKELPHPVK DLYWLNRVTS QAFNQRRKTL RNALSTLFTP 240
  241 EQLTALNIDL TARAENLSIA DYARLANWLA DNPPADVRRD EIIEENEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] PSI-BLAST 61.154902 2.1 Angstrom Crystal structure of KsgA: A Universally Conserved Adenosine Dimethyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  4.09362182773099 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  3.67177992319602 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  3.5512266163483 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  2.49492581548369 bayes_pls_golite062009
  • transferase activity
    		•  2.22303238506686 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  2.14498896320526 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  2.06652984530965 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  2.06652984530965 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  1.83964463328968 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  1.75675289134467 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  1.63076727020333 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.42049721553167 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  1.26493190370687 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  1.12859857407629 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  1.10713374933008 bayes_pls_golite062009
  • DNA binding
    		•  1.03011331296251 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.731396842794323 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  0.720411427168235 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  0.606920378432989 bayes_pls_golite062009
  • binding
    		•  0.546744797014504 bayes_pls_golite062009
  • mitochondrial transcription initiation factor activity
    		•  0.481383105532041 bayes_pls_golite062009
  • tRNA (cytosine-5-)-methyltransferase activity
    		•  0.299393192819978 bayes_pls_golite062009
  • tRNA (cytosine)-methyltransferase activity
    		•  0.299393192819978 bayes_pls_golite062009
  • rRNA (guanine-N1-)-methyltransferase activity
    		•  0.234572322347698 bayes_pls_golite062009
  • rRNA (uridine-2'-O-)-methyltransferase activity
    		•  0.188049877065151 bayes_pls_golite062009
  • transcription factor binding
    		•  0.149382105526243 bayes_pls_golite062009
  • rRNA (uridine) methyltransferase activity
    		•  0.130647573658872 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle