Protein Overview: gi|45441777, gi|...

General Information:
Name(s) found:	gi\|45441777 [NCBI NR] gi\|45436639 [NCBI NR]
Description(s) found: Found 4 descriptions. SHOW ALL	gi\|45441777\|ref\|NP_993316.1\| bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Yersinia pestis biovar Microtus str. 91001] [NCBI NR] gi\|45436639\|gb\|AAS62193.1\| aldehyde-alcohol dehydrogenase [Yersinia pestis biovar Microtus str. 91001] [NCBI NR]
Organism:	Yersinia pestis biovar Microtus str. 91001
Length:	891 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVTNVAELN ELVARVKKAQ REYANFSQEQ VDKIFRAAAL AAADARIPLA KLAVTESGMG  60
   61 IVEDKVIKNH FASEYIYNAY KDEKTCGILC EDKTFGTITI AEPIGLICGI VPTTNPTSTA 120
  121 IFKALISLKT RNGIIFSPHP RAKDATNKAA DIVLQAAIAA GAPADIIGWI DAPTVELSNQ 180
  181 LMHHPDINLI LATGGPGMVK AAYSSGKPAI GVGAGNTPVV VDETADIKRV VASILMSKTF 240
  241 DNGVICASEQ SIIVVDSVYD AVRERFASHG GYLLQGKELK AVQDIILKNG GLNAAIVGQP 300
  301 ATKIAEMAGI KVPSNTKILI GEVKVVDESE PFAHEKLSPT LAMYRAKNFE EAVEKAEKLV 360
  361 EMGGIGHTSC LYTDQDNQTA RVKYFGDKMK TARILINTPA SQGGIGDLYN FKLAPSLTLG 420
  421 CGSWGGNSIS ENVGPKHLIN KKTVAKRAEN MLWHKLPKSI YFRRGSLPIA LEEVATDGAK 480
  481 RAFIVTDRYL FNNGYADQVT SVLKSHGIET EVFFEVEADP TLSIVRKGAE QMNSFKPDVI 540
  541 IALGGGSPMD AAKIMWVMYE HPETHFEELA LRFMDIRKRI YKFPKMGVKA KLVAITTTSG 600
  601 TGSEVTPFAV VTDDATGQKY PLADYALTPD MAIVDANLVM NMPKSLCAFG GLDAVTHALE 660
  661 AYVSVLANEY SDGQALQALK LLKEFLPASY NEGAKNPVAR ERVHNAATIA GIAFANAFLG 720
  721 VCHSMAHKLG SEFHIPHGLA NAMLISNVIR YNANDNPTKQ TAFSQYDRPQ ARRRYAEIAD 780
  781 HLGLSAPGDR TAQKIQKLLA WLDEIKAELG IPASIREAGV QEADFLAKVD KLSEDAFDDQ 840
  841 CTGANPRYPL ISELKQILMD TYYGREYVEE FDREEEVAAA TAPKAEKKTK K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..447]	PSI-BLAST	135.0	Aldehyde reductase (dehydrogenase), ALDH
2	View Details	[448..891]	PSI-BLAST	96.522879	Crystal Structure of Lactaldehyde reductase

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
oxidoreductase activity	4.47226217021998	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	4.34495776828926	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	3.37049090049734	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity	3.30681232755737	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3.2867555127991	bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity	2.81851373615334	bayes_pls_golite062009
catalytic activity	2.80804701752928	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity	2.25908515251731	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	1.80313175632526	bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity	1.59279206536309	bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity	1.15620590715864	bayes_pls_golite062009
binding	0.637403449596354	bayes_pls_golite062009

2

Term	Confidence	Notes
hydroxyacid-oxoacid transhydrogenase activity	8.51876704052427	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	5.26400058766942	bayes_pls_golite062009
oxidoreductase activity	3.07409531087588	bayes_pls_golite062009
alcohol dehydrogenase activity, metal ion-independent	3.05722501802075	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.83823088483915	bayes_pls_golite062009
catalytic activity	2.37357608468991	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2.10085302216488	bayes_pls_golite062009
binding	1.15096180564234	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	0.831155115586418	bayes_pls_golite062009
cation binding	0.319000821544479	bayes_pls_golite062009
metal ion binding	0.319000821544479	bayes_pls_golite062009
ion binding	0.313606245452103	bayes_pls_golite062009
protein binding	0.295023706645045	bayes_pls_golite062009
transition metal ion binding	0.259889634539407	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0904828025133766	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.83

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle