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Protein Overview: CNN2_PONPY

General Information:
Name(s) found: CNN2_PONPY [Swiss-Prot]
Description(s) found:
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  • gi|75055290|sp|Q5RFN6.3|CNN2_PONAB RecName: Full=Calponin-2; AltName: Full=Calponin H2, smooth muscle; AltName: Full=Neutral calponin [NCBI NR]
  • gi|55725108|emb|CAH89421.1| hypothetical protein [Pongo abelii] [NCBI NR]
  • Calponin-2 - Pongo pygmaeus (Orangutan) [Swiss-Prot]
    • Organism: Pongo pygmaeus
    Length: 309 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTQFNKGP SYGLSAEVKN RLLSKYDPQK EAELRTWIEG LTGLSIGPDF QKGLKDGTIL  60
   61 CTLMNKLQPG SVPKINRSMQ NWHQLENLSN FIKAMVSYGM NPVDLFEAND LFESGNMTQV 120
  121 QVSLLALAGK AKTKGLQSGV DIGVKYSEKQ ERNFDDATMK AGQCVIGLQM GTNKCASQSG 180
  181 MTAYGTRRHL YDPKNHILPP MDHSTISLQM GTNKCASQVG MTAPGTRRHI YDTKLGTDKC 240
  241 DNSSMSLQMG YTQGANQSGQ VFGLGRQIYD PKYCPQGTVA DGAPSGTGDC PDPGEVPEYP 300
  301 PYYQEEAGY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] PSI-BLAST 42.221849 Solution structure of the CH domain of human calponin-2
    2 View Details [160..240] PSI-BLAST 7.522879 Solution structure of SH3 domain in Rac/Cdc42 guanine nucleotide exchange factor(GEF) 6
    3 View Details [241..309] MSA 2.050982 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • actin binding
    		•  4.94949685871786 bayes_pls_golite062009
  • structural constituent of muscle
    		•  4.65743655357495 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.41722924924158 bayes_pls_golite062009
  • actin filament binding
    		•  3.69427077755816 bayes_pls_golite062009
  • binding
    		•  3.06905798270146 bayes_pls_golite062009
  • protein binding
    		•  2.08632303609243 bayes_pls_golite062009
  • signal transducer activity
    		•  1.34867629228264 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.34867629228264 bayes_pls_golite062009
  • vinculin binding
    		•  1.06656350652527 bayes_pls_golite062009
  • transporter activity
    		•  0.896907103596953 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.713068405985864 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.500685400112742 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.371928447183203 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.272368655500689 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.00318812576030902 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle