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Protein Overview: NUSA_SHIFL

General Information:
Name(s) found: NUSA_SHIFL [Swiss-Prot]
Description(s) found:
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  • gi|84028776|sp|P0AFF9.1|NUSA_SHIFL RecName: Full=Transcription elongation protein nusA; AltName: Full=N utilization substance protein A; AltName: Full=L factor [NCBI NR]
  • sp|P03003|NUSA_ECOLI Transcription elongation protein nusA (N utilization substance protein A) (L factor) [NCBI NR]
  • Transcription termination/antitermination protein NusA OS=Shigella flexneri GN=nusA PE=3 SV=1 [Swiss-Prot]
  • transcription pausing; L factor [Escherichia coli K12]gi|15833304|ref|NP_312077.1| NusA; transcription termination-antitermination factor [Escherichia coli O157:H7]gi|30064509|ref|NP_838680.1| transcription pausing; L factor [Shigella flexneri 2a str. 2 [nrdb_11152004_Chlamydomonas]
  • Transcription elongation protein nusA (N utilization substance protein A) (L factor) [nr-271106-contam.fasta]
    • Organism: Shigella flexneri
    Length: 495 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKEILAVVE AVSNEKALPR EKIFEALESA LATATKKKYE QEIDVRVQID RKSGDFDTFR  60
   61 RWLVVDEVTQ PTKEITLEAA RYEDESLNLG DYVEDQIESV TFDRITTQTA KQVIVQKVRE 120
  121 AERAMVVDQF REHEGEIITG VVKKVNRDNI SLDLGNNAEA VILREDMLPR ENFRPGDRVR 180
  181 GVLYSVRPEA RGAQLFVTRS KPEMLIELFR IEVPEIGEEV IEIKAAARDP GSRAKIAVKT 240
  241 NDKRIDPVGA CVGMRGARVQ AVSTELGGER IDIVLWDDNP AQFVINAMAP ADVASIVVDE 300
  301 DKHTMDIAVE AGNLAQAIGR NGQNVRLASQ LSGWELNVMT VDDLQAKHQA EAHAAIDTFT 360
  361 KYLDIDEDFA TVLVEEGFST LEELAYVPMK ELLEIEGLDE PTVEALRERA KNALATIAQA 420
  421 QEESLGDNKP ADDLLNLEGV DRDLAFKLAA RGVCTLEDLA EQGIDDLADI EGLTDEKAGA 480
  481 LIMAARNICW FGDEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..361] PSI-BLAST 105.0 Crystal structure of NusA from Thermotoga maritima: a structure-based role of the N-terminal domain
    2 View Details [362..428] PSI-BLAST 14.39794 NMR structure of the carboxyterminal domains of Escherichia coli NusA
    3 View Details [429..495] PSI-BLAST 21.09691 NMR structure of the carboxyterminal domains of Escherichia coli NusA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription termination factor activity
    		•  5.95012300460543 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.08684997768441 bayes_pls_golite062009
  • binding
    		•  1.8883583267074 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.20938494814687 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.860693644487058 bayes_pls_golite062009
  • DNA binding
    		•  0.814370062643769 bayes_pls_golite062009
  • protein binding
    		•  0.731201599320953 bayes_pls_golite062009
  • structural molecule activity
    		•  0.570047646271216 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.440010017405756 bayes_pls_golite062009
  • translation regulator activity
    		•  0.31332179848255 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.263197317040851 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.19668406318255 bayes_pls_golite062009
  • catalytic activity
    		•  0.10089766806364 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle