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Protein Overview: gi|75226958

General Information:
Name(s) found: gi|75226958 [NCBI NR]
Description(s) found:
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  • gi|75226958|ref|ZP_00713833.1| COG0466: ATP-dependent Lon protease, bacterial type [Escherichia coli B7A] [NCBI NR]
  • COG0466: ATP-dependent Lon protease, bacterial type [Escherichia coli B7A] [nr-271106-contam.fasta]
    • Organism: Escherichia coli B7A
    Length: 784 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPERSERIE IPVLPLRDVV VYPHMVIPLF VGREKSIRCL EAAMDHDKKI MLVAQKEAST  60
   61 DEPGVNDLFT VGTVASILQM LKLPDGTVKV LVEGLQRARI SALSDNGEHF SAKAEYLESP 120
  121 TIDEREQEVL VRTAISQFEG YIKLNKKIPP EVLTSLNSID DPARLADTIA AHMPLKLADK 180
  181 QSVLEMSDVN ERLEYLMAMM ESEIDLLQVE KRIRNRVKKQ MEKSQREYYL NEQMKAIQKE 240
  241 LGEMDDAPDE NEALKRKIDA AKMPKEAKEK AEAELQKLKM MSPMSAEATV VRGYIDWMVQ 300
  301 VPWNARSKVK KDLRQAQEIL DTDHYGLERV KDRILEYLAV QSRVNKIKGP ILCLVGPPGV 360
  361 GKTSLGQSIA KATGRKYVRM ALGGVRDEAE IRGHRRTYIG SMPGKLIQKM AKVGVKNPLF 420
  421 LLDEIDKMSS DMRGDPASAL LEVLDPEQNV AFSDHYLEVD YDLSDVMFVA TSNSMNIPAP 480
  481 LLDRMEVIRL SGYTEDEKLN IAKRHLLPKQ IERNALKKGE LTVDDSAIIG IIRYYTREAG 540
  541 VRGLEREISK LCRKAVKQLL LDKSLKHIEI NGDNLHDYLG VQRFDYGRAD NENRVGQVTG 600
  601 LAWTEVGGDL LTIETACVPG KGKLTYTGSL GEVMQESIQA ALTVVRARAE KLGINPDFYE 660
  661 KRDIHVHVPE GATPKDGPSA GIAMCTALVS CLTGNPVRAD VAMTGEITLR GQVLPIGGLK 720
  721 EKLLAAHRGG IKTVLIPFEN KRDLEEIPDN VIADLDIHPV KRIEEVLTLA LQNEPSGMQV 780
  781 VTAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] PSI-BLAST 35.221849 Crystal structure of N-terminal domain of E.Coli Lon Protease
    2 View Details [120..203] FFAS03 1.93 Crystal Structure of the Hypothetical Protein BPP1347 from Bordetella parapertussis, Northeast Structural Genomics Target BoR27.
    3 View Details [204..306] FFAS03 1.94 Complex of Hsp90 and P50
    4 View Details [307..492] PSI-BLAST 24.154902 No description for 2qp9X was found.
    5 View Details [493..607] FFAS03 5.2 Structure of Bacillus subtilis Lon protease SSD domain
    6 View Details [608..784] PSI-BLAST 47.154902 Catalytic domain of E.coli Lon protease

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.679730538301274 bayes_pls_golite062009
  • protein binding
    		•  0.3997153647519 bayes_pls_golite062009
  • catalytic activity
    		•  0.147263815852997 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  0.447741978121551 bayes_pls_golite062009
  • catalytic activity
    		•  0.174240748624544 bayes_pls_golite062009
  • protein binding
    		•  0.134860723832737 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  0.910427157976578 bayes_pls_golite062009
  • protein binding
    		•  0.666389745132759 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • hydrolase activity
    		•  1.18773479836745 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • peptidase activity
    		•  0.677675533122378 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.543314877411748 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.444922294492883 bayes_pls_golite062009
  • binding
    		•  0.423668529068616 bayes_pls_golite062009
  • structural molecule activity
    		•  0.278122898090466 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.214389253755211 bayes_pls_golite062009
  • protein binding
    		•  0.214066724623027 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle