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Protein Overview: gi|75515259

General Information:
Name(s) found: gi|75515259 [NCBI NR]
Description(s) found:
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  • gi|75515259|ref|ZP_00737443.1| COG1194: A/G-specific DNA glycosylase [Escherichia coli 53638] [NCBI NR]
  • COG1194: A/G-specific DNA glycosylase [Escherichia coli 53638] [nr-271106-contam.fasta]
    • Organism: Escherichia coli 53638
    Length: 350 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQASQFSAQV LDWYDKYGRK TLPWQIDKTP YKVWLSEVML QQTQVATVIP YFERFMARFP  60
   61 TVTDLANAPL DEVLHLWTGL GYYARARNLH KAAQQVATLH GGKFPETFEE VAALPGVGRS 120
  121 TAGAILSLSL GKHFPILDGN VKRVLARCYA VSGWPGKKEV ENKLWSLSEQ VTPAVGVERF 180
  181 NQAMMDLGAM ICTRSKPKCS LCPLQNGCIA AANNSWALYP GKKPKQTLPE RTGYFLLLQH 240
  241 EDEVLLAQRP PSGLWGGLYC FPQFADEESL RQWLAQRQIA ADNLTQLTAF RHTFSHFHLD 300
  301 IVPMWLPVSS FTGCMDEGNA LWYNLAQPPS VGLAAPVERL LQQLRTGAPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] PSI-BLAST 59.39794 Catalytic domain of MutY
    2 View Details [221..350] PSI-BLAST 15.69897 NMR STUDY OF MUTT ENZYME, A NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA N-glycosylase activity
    		•  4.8124964619976 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing N-glycosyl compounds
    		•  4.26870112679392 bayes_pls_golite062009
  • DNA-(apurinic or apyrimidinic site) lyase activity
    		•  3.71152530486175 bayes_pls_golite062009
  • oxidized base lesion DNA N-glycosylase activity
    		•  2.49872706126491 bayes_pls_golite062009
  • hydrolase activity
    		•  2.39042189031819 bayes_pls_golite062009
  • 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
    		•  2.21048599823382 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  2.18053745735048 bayes_pls_golite062009
  • catalytic activity
    		•  2.13345932727422 bayes_pls_golite062009
  • damaged DNA binding
    		•  2.00388798014411 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.77735453133546 bayes_pls_golite062009
  • DNA binding
    		•  1.70910448624199 bayes_pls_golite062009
  • alkylbase DNA N-glycosylase activity
    		•  1.5832578018127 bayes_pls_golite062009
  • oxidized purine base lesion DNA N-glycosylase activity
    		•  1.32985950765371 bayes_pls_golite062009
  • oxidized pyrimidine base lesion DNA N-glycosylase activity
    		•  1.2016453685638 bayes_pls_golite062009
  • binding
    		•  1.15752946565805 bayes_pls_golite062009
  • DNA-3-methyladenine glycosylase I activity
    		•  1.06383943982125 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.953912155797942 bayes_pls_golite062009
  • uracil DNA N-glycosylase activity
    		•  0.879508131574476 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.85419760398899 bayes_pls_golite062009
  • purine-specific mismatch base pair DNA N-glycosylase activity
    		•  0.68578837518217 bayes_pls_golite062009
  • mismatch base pair DNA N-glycosylase activity
    		•  0.661651574677137 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.57099109384393 bayes_pls_golite062009
  • transcription factor activity
    		•  0.181268475863531 bayes_pls_golite062009
  • protein binding
    		•  0.0921713980805489 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.0676784802238829 bayes_pls_golite062009
    2
    Term Confidence Notes
  • MutLbeta complex binding
    		•  3.54991362477413 bayes_pls_golite062009
  • MutSbeta complex binding
    		•  3.54991362477413 bayes_pls_golite062009
  • hydrolase activity
    		•  1.97832429767892 bayes_pls_golite062009
  • catalytic activity
    		•  1.49075808737475 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.06392208444166 bayes_pls_golite062009
  • binding
    		•  0.804982034963737 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.546676461152337 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.00783582682768413 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle