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Protein Overview: sv-PE

General Information:
Name(s) found: sv-PE / FBpp0099748 [FlyBase]
Description(s) found:
Found 10 descriptions.
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  • The gene shaven is referred to in FlyBase by the symbol Dmel\sv (CG11049, FBgn0005561). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:1109444..1133943. It has the cytological map location 102F8. It is reported to have molecular function</span>: RNA polymerase II transcription factor activity; transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; neuron development; muscle organ development. 52 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: peripheral nervous system; external compound sense organ; nervous system; organ system; adult segment; compound cell cluster organ; rhabdomere; imaginal precursor; antennal segment; primary pigment cell; cell projection; unguis; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 794 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    Biological Process: muscle organ development [IMP]
    neuron development [IMP]
    regulation of transcription [IEA][NAS]
    compound eye cone cell fate commitment [TAS]
    dendrite morphogenesis [IMP]
    Molecular Function: DNA binding [IEA]
    transcription factor activity [TAS]
    RNA polymerase II transcription factor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIMDIQTST HHIHGLGTHE LQHRILHPHI LHSTQEETLN TSTGQLEHDS QHLQQHHLTH  60
   61 HQQQDVSPTL HNLQNTRTGD SLSTTINTNQ NQHGHQHLSG SNMYTSSQME DKSKANKYDE 120
  121 YSSRTLSNIS DANTTPSANN FITQSQGIEW ITAMNDIQNG AEDSHSSQGS ISGDGHGGVN 180
  181 QLGGVFVNGR PLPDVVRQRI VELAHNGVRP CDISRQLRVS HGCVSKILSR YYETGSFKAG 240
  241 VIGGSKPKVA TPPVVDAIAN YKRENPTMFA WEIRDRLLAE AICSQDNVPS VSSINRIVRN 300
  301 KAAEKAKHVH HHQQHHVSQS LGGGHIATES VDSSTGTIGE PQPPTSNSSA NSVNTNVSAS 360
  361 ASVHASIPTS GTDSVQVSVG HINANSNETT HINSTAEQRT TGYSINGILG IQHGHHSHNN 420
  421 NNNSSVNNNN NTESSCKRKR IEAHDENHDT NIHSDNDDGK RQRMSTYSGD QLYTNIWSGK 480
  481 WCIKDDHKLL AELGNLTAST GNCPATYYEA SNGFSTTPIS GSGATASGND TSMLYDSITT 540
  541 ISQTQSSIYT PAIGPSIGTG SLTPLVPISM HEMKLSANSI QEQTVPPFYT ALAFDGNYTS 600
  601 MTSLENCSSL VGQEHIVMPE SSDSNTLCPI STRIVPDITE TNSTRVKEPL TNSDGCSEDN 660
  661 NKEPEKSNSS QSSDHIASPH LHHIGEEQLR GNRRSNLNAS THPSSLIPLQ PSGGSSLLNI 720
  721 NPSENRSDVE LNLSNNVGLY STPTVLPSFN HYSAGFLYFQ AAAQLYPVQI TPTILHIPSM 780
  781 VELTDHMVTA LAVA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..161] deduced N/A No confident structure predictions are available.
    2 View Details [162..373] PSI-BLAST 64.045757 Pax-5
    3 View Details [374..618] deduced N/A No confident structure predictions are available.
    4 View Details [619..794] MSA 5.243993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.5139760613123 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.16896789933192 bayes_pls_golite062009
  • transcription activator activity
    		•  3.10621734076555 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • protein binding
    		•  1.88087411289001 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.73068440195944 bayes_pls_golite062009
  • chromatin binding
    		•  1.68956710349366 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle