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Protein Overview: lbl-PB

General Information:
Name(s) found: lbl-PB / FBpp0289338 [FlyBase]
Description(s) found:
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  • gi|66571118|gb|AAY51524.1| IP08853p [Drosophila melanogaster] [NCBI NR]
  • gi|221458207|ref|NP_001138092.1| ladybird late, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|220903158|gb|ACL83548.1| ladybird late, isoform B [Drosophila melanogaster] [NCBI NR]
  • The gene ladybird late is referred to in FlyBase by the symbol Dmel\lbl (CG6570, FBgn0008651). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17235701..17259845. It has the cytological map location 93E1. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; genital disc morphogenesis; regulation of neuron differentiation; skeletal muscle tissue development; regulation of transcription; cell migration; epidermis development; regulation of cell fate specification. 8 alleles are reported. The phenotypes of these alleles are annotated with: prothoracic segmental nerve; central nervous system; intersegmental nerve; dorsal denticle; EL neuron. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • type=protein; loc=3R:complement(17252644..17252825,17258987..17259689); ID=FBpp0289338; name=lbl-PB; parent=FBgn0008651,FBtr0300061; dbxref=FlyBase:FBpp0289338,FlyBase_Annotation_IDs:CG6570-PB,REFSEQ:NP_001138092,GB_protein:ACL83548; MD5=6dc538215acbc6ea4 [fly-100309-contam.fasta]
  • IP08853p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(17252644..17252825,17258987..17259689); ID=FBpp0289338; name=lbl-PB; parent=FBgn0008651,FBtr0300061; dbxref=FlyBase:FBpp0289338,FlyBase_Annotation_IDs:CG6570-PB,REFSEQ:NP_001138092,GB_protein:ACL83548; MD5=6dc538215acbc6ea4983b460ffb52026; length=294; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(17252644..17252825,17258987..17259689); ID=FBpp0289338; name=lbl-PB; parent=FBgn0008651,FBtr0300061; dbxref=FlyBase:FBpp0289338,FlyBase_Annotation_IDs:CG6570-PB,REFSEQ:NP_001138092,GB_protein:ACL83548; MD5=6dc538215acbc6ea4983b460ffb52026; length=294; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • IP08853p OS=Drosophila melanogaster GN=lbl PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(17252644..17252825,17258987..17259689); ID=FBpp0289338; name=lbl-PB; parent=FBgn0008651,FBtr0300061; dbxref=FlyBase:FBpp0289338,FlyBase_Annotation_IDs:CG6570-PB,REFSEQ:NP_001138092,GB_protein:ACL83548,FlyMine:FBpp0289338,modMine:FBpp0289338; MD5=6dc538215acbc6ea4983b460ffb52026; length=294; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(21433265..21433967,21426922..21427103)); ID=FBpp0289338; name=lbl-PB; parent=FBgn0008651,FBtr0300061; dbxref=FlyBase:FBpp0289338,FlyBase_Annotation_IDs:CG6570-PB,REFSEQ:NP_001138092,GB_protein:ACL83548,FlyMine:FBpp0289338,modMine:FBpp0289338; MD5=6dc538215acbc6ea4983b460ffb52026; length=294; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(21433265..21433967,21426922..21427103)); ID=FBpp0289338; name=lbl-PB; parent=FBgn0008651,FBtr0300061; dbxref=FlyBase:FBpp0289338,FlyBase_Annotation_IDs:CG6570-PB,REFSEQ:NP_001138092,GB_protein:ACL83548,FlyMine:FBpp0289338,modMine:FBpp0289338; MD5=6dc538215acbc6ea4983b460ffb52026; length=294; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A0A0B4KH37, IP08853p OS=Drosophila melanogaster GN=lbl PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0289338 type=protein; loc=3R:complement(join(21433265..21433967,21426922..21427103)); ID=FBpp0289338; name=lbl-PB; parent=FBgn0008651,FBtr0300061; dbxref=FlyBase:FBpp0289338,FlyBase_Annotation_IDs:CG6570-PB,REFSEQ:NP_001138092,GB_protein:ACL83548,FlyMine:FBpp0289338,modMine:FBpp0289338; MD5=6dc538215acbc6ea4983b460ffb52026; length=294; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(21433265..21433967,21426922..21427103)); ID=FBpp0289338; name=lbl-PB; parent=FBgn0008651,FBtr0300061; dbxref=FlyBase:FBpp0289338,FlyBase_Annotation_IDs:CG6570-PB,REFSEQ:NP_001138092,GB_protein:ACL83548,UniProt/TrEMBL:Q4V727,FlyMine:FBpp0289338,modMine:FBpp0289338; MD5=6dc538215acbc6ea4983b460ffb52026; length=294; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 294 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    Biological Process: regulation of cell fate specification [IMP]
    genital disc morphogenesis [IMP]
    epidermis development [IMP]
    myoblast fusion [IGI]
    regulation of transcription, DNA-dependent [IEA]
    regulation of neuron differentiation [IMP]
    regulation of transcription [IEA][IMP][ISS]
    mesodermal cell fate specification [TAS]
    muscle organ development [TAS]
    heart development [TAS]
    central nervous system development [NAS]
    skeletal muscle tissue development [IGI]
    cell migration [IGI]
    Molecular Function: transcription factor activity [IEA]
    specific RNA polymerase II transcription factor activity [ISS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQRTPSPAN SDVSVGSPSP PPLRSLNMKR LRLLRSPISL EHDRQKSSPV RVKSFSIADI  60
   61 LGRGHEEDRV EKKPERIAIP NALPGVPAPL ALINERLQIP LVPNCPPPAA LHTFLSPALL 120
  121 HSYEQRLAWD YQRQLQEHFQ AQAQLLRQMT LNPAIIASED GSSERSQRSS SSNGSTECCS 180
  181 PTQAEKVEKR SQEDRMEVPK KSPEEQPKGA SKSSGDTPLD ALFQLSTKNF DEEQVSTSKR 240
  241 HSALRWNIFE TSPKSKGTKG ITNAGMNGKL SDLEKQAQVG VIVDVDVAIY TQHD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle