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Protein Overview: YAT1

General Information:
Name(s) found: YAT1 / YAR035W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 687 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: alcohol metabolic process [IGILink to PubMed article]
    carnitine metabolic process [IMPLink to PubMed article]
    Molecular Function: carnitine O-acetyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNLKRLPIP PLQDTLNRYL ARVEPLQDER QNRRTRRTVL SAENLDALNT LHERLLEYDA  60
   61 RLAESNPESS YIEQFWYDAY LLYDATVVLN VNPYFQLQDD PTIKDTPETA AQGPYGAHTV 120
  121 QVRRAARLTT SILKFIRQIR HGTLRTDTVR GKTPLSMDQY ERLFGSSRIP PGPGEPSCHL 180
  181 QTDATSHHVV AMYRGQFYWF DVLDTRNEPI FATPEQLEWN LYSIIMDAES AGSGSAPFGV 240
  241 FTTESRRVWS NIRDYLFHAD DCTNWRNLKL IDSALFVVCL DDVAFAADQQ DELTRSMLCG 300
  301 TSTINLDPHQ HQPPLNVQTG TCLNRWYDKL QLIVTKNGKA GINFEHTGVD GHTVLRLATD 360
  361 IYTDSILSFA RGVTKNVVDI FSDDDGKPSS SSLASAAHSA NLITIPRKLE WRTDNFLQSS 420
  421 LHFAETRISD LISQYEFVNL DFSNYGASHI KTVFKCSPDA FVQQVFQVAY FALYGRFETV 480
  481 YEPAMTKAFQ NGRTEAIRSV TGQSKLFVKS LLDQDASDAT KIQLLHDACT AHSQITRECS 540
  541 QGLGQDRHLY ALYCLWNQWY KDKLELPPIF RDKSWTTMQN NVLSTSNCGN PCLKSFGFGP 600
  601 VTANGFGIGY IIRDHSVSVV VSSRHRQTAR FASLMEKSLL EIDRIFKRQQ ARAAKPAART 660
  661 TASANTKSED MKYLLSGYDY FDVSVSG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CAT2 YAT1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YHR122W YAT1 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..687] Pfam 294.886057 Choline/Carnitine o-acyltransferase No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle